ID O96525_DROME Unreviewed; 413 AA. AC O96525; DT 01-MAY-1999, integrated into UniProtKB/TrEMBL. DT 01-MAY-1999, sequence version 1. DT 05-OCT-2010, entry version 41. DE SubName: Full=Unpaired protein; GN Name=os; Synonyms=unpaired; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=99003077; PubMed=9784499; RA Harrison D.A., McCoon P.E., Binari R., Gilman M., Perrimon N.; RT "Drosophila unpaired encodes a secreted protein that activates the JAK RT signaling pathway."; RL Genes Dev. 12:3252-3263(1998). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF072823; AAC69620.1; -; mRNA. DR IntAct; O96525; 1. DR STRING; O96525; -. DR PRIDE; O96525; -. DR EnsemblMetazoa; FBtr0074581; FBpp0074353; FBgn0004956. DR EnsemblMetazoa; FBtr0112847; FBpp0111760; FBgn0004956. DR FlyBase; FBgn0004956; os. DR InParanoid; O96525; -. DR ArrayExpress; O96525; -. DR Bgee; O96525; -. DR GO; GO:0005578; C:proteinaceous extracellular matrix; TAS:FlyBase. DR GO; GO:0005125; F:cytokine activity; TAS:FlyBase. DR GO; GO:0016015; F:morphogen activity; NAS:FlyBase. DR GO; GO:0003383; P:apical constriction; IMP:FlyBase. DR GO; GO:0007350; P:blastoderm segmentation; TAS:FlyBase. DR GO; GO:0007298; P:border follicle cell migration; IMP:FlyBase. DR GO; GO:0001700; P:embryonic development via the syncytial bla...; TAS:FlyBase. DR GO; GO:0007455; P:eye-antennal disc morphogenesis; IMP:FlyBase. DR GO; GO:0007440; P:foregut morphogenesis; IMP:FlyBase. DR GO; GO:0042078; P:germ-line stem cell division; TAS:FlyBase. DR GO; GO:0007442; P:hindgut morphogenesis; IMP:FlyBase. DR GO; GO:0007259; P:JAK-STAT cascade; TAS:FlyBase. DR GO; GO:0060031; P:mediolateral intercalation; IMP:FlyBase. DR GO; GO:0046427; P:positive regulation of JAK-STAT cascade; IDA:FlyBase. DR GO; GO:0016476; P:regulation of embryonic cell shape; IMP:FlyBase. DR GO; GO:0007540; P:sex determination, establishment of X:A ratio; NAS:FlyBase. DR GO; GO:0048103; P:somatic stem cell division; TAS:FlyBase. PE 2: Evidence at transcript level; KW Complete proteome. SQ SEQUENCE 413 AA; 46926 MW; C987C3599AD5EFE5 CRC64; MARPLLLLLP ILLVLLLAAQ LPHLAEGRST TSSGGLTVID SERLPIRTTS STASAQHPNQ GTIPASAASP RKRHRKRNSN WIDYRNFDEN TTALEWANPC GGNYHPSAGD RFNRQRPRQS FNQLKRHAFR EYRSLNSSQD SAIDIRNMTM WSLHTHNYKF LPKLKPNSTI ALKRWYRNMQ TYVASFAYLR RQQIRWDQRS ITRESSTARE LRELLLSSRR ILCELETAVN QTQSPRQKQR RSGAAVTAVG GTTMLGQQLP QISRLEMNKR LKLRSKTSGP GMGGAASSAS MAAGEADSID MRFVKHHYYD FLRTMYQLLR RDGKRVRSRP RKHHKKQQRS QKKLLQQQQQ LADQLEQRWR SSTLNGKEFN EVSKPVAGGA AGVADVAGVS GGGSNQFARG RRGKRQSKRV QRT //