ID O96525_DROME Unreviewed; 413 AA. AC O96525; DT 01-MAY-1999, integrated into UniProtKB/TrEMBL. DT 01-MAY-1999, sequence version 1. DT 06-FEB-2007, entry version 20. DE Unpaired protein. GN Name=os; Synonyms=unpaired; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=99003077; PubMed=9784499; RA Harrison D.A., McCoon P.E., Binari R., Gilman M., Perrimon N.; RT "Drosophila unpaired encodes a secreted protein that activates the JAK RT signaling pathway."; RL Genes Dev. 12:3252-3263(1998). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF072823; AAC69620.1; -; mRNA. DR FlyBase; FBgn0004956; os. DR GO; GO:0005578; C:extracellular matrix (sensu the Metazoa res...; TAS:FlyBase. DR GO; GO:0005125; F:cytokine activity; TAS:FlyBase. DR GO; GO:0016015; F:morphogen activity; NAS:FlyBase. DR GO; GO:0007350; P:blastoderm segmentation; TAS:FlyBase. DR GO; GO:0007298; P:border follicle cell migration (sensu the I...; IMP:FlyBase. DR GO; GO:0007298; P:border follicle cell migration (sensu the I...; TAS:FlyBase. DR GO; GO:0001700; P:embryonic development (sensu the Insecta re...; TAS:FlyBase. DR GO; GO:0007440; P:foregut morphogenesis; IMP:FlyBase. DR GO; GO:0042078; P:germ-line stem cell division; TAS:FlyBase. DR GO; GO:0007442; P:hindgut morphogenesis; IMP:FlyBase. DR GO; GO:0007259; P:JAK-STAT cascade; TAS:FlyBase. DR GO; GO:0007540; P:sex determination, establishment of X:A ratio; NAS:FlyBase. DR GO; GO:0048103; P:somatic stem cell division; TAS:FlyBase. SQ SEQUENCE 413 AA; 46926 MW; C987C3599AD5EFE5 CRC64; MARPLLLLLP ILLVLLLAAQ LPHLAEGRST TSSGGLTVID SERLPIRTTS STASAQHPNQ GTIPASAASP RKRHRKRNSN WIDYRNFDEN TTALEWANPC GGNYHPSAGD RFNRQRPRQS FNQLKRHAFR EYRSLNSSQD SAIDIRNMTM WSLHTHNYKF LPKLKPNSTI ALKRWYRNMQ TYVASFAYLR RQQIRWDQRS ITRESSTARE LRELLLSSRR ILCELETAVN QTQSPRQKQR RSGAAVTAVG GTTMLGQQLP QISRLEMNKR LKLRSKTSGP GMGGAASSAS MAAGEADSID MRFVKHHYYD FLRTMYQLLR RDGKRVRSRP RKHHKKQQRS QKKLLQQQQQ LADQLEQRWR SSTLNGKEFN EVSKPVAGGA AGVADVAGVS GGGSNQFARG RRGKRQSKRV QRT //