ID O96525_DROME PRELIMINARY; PRT; 413 AA. AC O96525; DT 01-MAY-1999 (TrEMBLrel. 10, Created) DT 01-MAY-1999 (TrEMBLrel. 10, Last sequence update) DT 01-MAR-2004 (TrEMBLrel. 26, Last annotation update) DE Unpaired protein. GN Name=os; Synonyms=unpaired; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=99003077; PubMed=9784499; RA Harrison D.A., McCoon P.E., Binari R., Gilman M., Perrimon N.; RT "Drosophila unpaired encodes a secreted protein that activates the JAK RT signaling pathway."; RL Genes Dev. 12:3252-3263(1998). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF072823; AAC69620.1; -; mRNA. DR FlyBase; FBgn0004956; os. DR GO; GO:0005578; C:extracellular matrix (sensu Metazoa); TAS. DR GO; GO:0005125; F:cytokine activity; TAS. DR GO; GO:0016015; F:morphogen activity; NAS. DR GO; GO:0007350; P:blastoderm segmentation; TAS. DR GO; GO:0007298; P:border follicle cell migration (sensu Insecta); IMP. DR GO; GO:0001700; P:embryonic development (sensu Insecta); TAS. DR GO; GO:0007440; P:foregut morphogenesis; IMP. DR GO; GO:0042078; P:germ-line stem cell division; TAS. DR GO; GO:0007442; P:hindgut morphogenesis; IMP. DR GO; GO:0007259; P:JAK-STAT cascade; TAS. DR GO; GO:0030707; P:ovarian follicle cell development (sensu In...; IMP. DR GO; GO:0007538; P:primary sex determination; IMP. DR GO; GO:0007540; P:sex determination, establishment of X:A ratio; NAS. DR GO; GO:0048103; P:somatic stem cell division; TAS. SQ SEQUENCE 413 AA; 46926 MW; C987C3599AD5EFE5 CRC64; MARPLLLLLP ILLVLLLAAQ LPHLAEGRST TSSGGLTVID SERLPIRTTS STASAQHPNQ GTIPASAASP RKRHRKRNSN WIDYRNFDEN TTALEWANPC GGNYHPSAGD RFNRQRPRQS FNQLKRHAFR EYRSLNSSQD SAIDIRNMTM WSLHTHNYKF LPKLKPNSTI ALKRWYRNMQ TYVASFAYLR RQQIRWDQRS ITRESSTARE LRELLLSSRR ILCELETAVN QTQSPRQKQR RSGAAVTAVG GTTMLGQQLP QISRLEMNKR LKLRSKTSGP GMGGAASSAS MAAGEADSID MRFVKHHYYD FLRTMYQLLR RDGKRVRSRP RKHHKKQQRS QKKLLQQQQQ LADQLEQRWR SSTLNGKEFN EVSKPVAGGA AGVADVAGVS GGGSNQFARG RRGKRQSKRV QRT //