ID O92593_9HIV1 Unreviewed; 211 AA. AC O92593; DT 01-NOV-1998, integrated into UniProtKB/TrEMBL. DT 01-NOV-1998, sequence version 1. DT 16-DEC-2008, entry version 44. DE RecName: Full=Protein Nef; GN Name=nef; OS Human immunodeficiency virus 1. OC Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae; OC Lentivirus; Primate lentivirus group. OX NCBI_TaxID=11676; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=3715; RA Ahmad K.M., Jameel S.; RT "NEF sequences of primary hiv-1 isolates from northern India."; RL Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the lentivirus primate group Nef protein CC family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Y18199; CAA77077.1; -; Genomic_RNA. DR HSSP; P04324; 1ZEC. DR SMR; O92593; 2-61, 60-210. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW. DR GO; GO:0005525; F:GTP binding; IEA:InterPro. DR GO; GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW. DR GO; GO:0009405; P:pathogenesis; IEA:UniProtKB-KW. DR InterPro; IPR001558; HIV_Nef. DR Gene3D; G3DSA:3.30.62.10; HIV_Nef; 1. DR Pfam; PF00469; F-protein; 1. DR ProDom; PD000031; HIV_Nef; 1. PE 3: Inferred from homology; KW Cell membrane; Membrane. SQ SEQUENCE 211 AA; 24238 MW; 92AB590B99EA60A7 CRC64; MGGKWSKSSI VGWPAIRERM RRTEPAAEPA AEGVGAASQD LDRHGALTSS NTDTNNADCA WLRAQEEEEE VGFPVRPQVP LRPMTFKGAF DLSFFLKEKG GLEGLIYSKK RQEILDLWVY RTQGYFPDWQ NYTPGPGERF PLTFGWCFKL VPVDPREVEE ANEGEDNSLL HPVCQHGMED EHREVLKWKF DSQLALRHRA RELHPEFYKD C //