ID   O86886_STREE            Unreviewed;       243 AA.
AC   O86886;
DT   01-NOV-1998, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1998, sequence version 1.
DT   11-MAY-2016, entry version 66.
DE   SubName: Full=Cap33fB protein {ECO:0000313|EMBL:CAA07395.1};
DE   SubName: Full=Capsular polysaccharide {ECO:0000313|EMBL:AEV23243.1};
DE   SubName: Full=Pneumococcal capsular regulatory tyrosine phosphatase {ECO:0000313|EMBL:AEY99872.1};
DE   SubName: Full=Pneumococcal capsular tyrosine kinase phosphatase {ECO:0000313|EMBL:AEY99926.1};
DE   SubName: Full=Protein-tyrosine phosphatase Wzh {ECO:0000313|EMBL:CAI33504.1};
DE            EC=3.1.3.48 {ECO:0000313|EMBL:CAI33504.1, ECO:0000313|EMBL:CEV40578.1};
DE   SubName: Full=Tyrosine-protein phosphatase CpsB {ECO:0000313|EMBL:CEV40578.1};
GN   Name=cap33fB {ECO:0000313|EMBL:CAA07395.1};
GN   Synonyms=cps17fB {ECO:0000313|EMBL:AEY99908.1}, cps24bB
GN   {ECO:0000313|EMBL:AEY99872.1}, cps24fB {ECO:0000313|EMBL:AEY99873.1},
GN   cps33cB {ECO:0000313|EMBL:AEY99880.1}, cps33dB
GN   {ECO:0000313|EMBL:AEY99881.1}, cps35aB {ECO:0000313|EMBL:AEY99884.1},
GN   cps35B {ECO:0000313|EMBL:AEY99926.1}, cps35bB
GN   {ECO:0000313|EMBL:AEY99885.1}, cpsB {ECO:0000313|EMBL:AEV23243.1},
GN   cpsB_1 {ECO:0000313|EMBL:COM84528.1}, wzh
GN   {ECO:0000313|EMBL:CAI33504.1};
GN   ORFNames=ERS020514_00988 {ECO:0000313|EMBL:CEV40578.1},
GN   ERS020522_01732 {ECO:0000313|EMBL:COE69210.1}, ERS020523_01830
GN   {ECO:0000313|EMBL:COE95193.1}, ERS020692_00076
GN   {ECO:0000313|EMBL:COM84528.1}, ERS043947_00361
GN   {ECO:0000313|EMBL:CTL53763.1}, SPC17F_0004
GN   {ECO:0000313|EMBL:CAI33504.1}, SPC33A_0005
GN   {ECO:0000313|EMBL:CAI34168.1}, SPC33C_0005
GN   {ECO:0000313|EMBL:CAI34208.1}, SPC33F_0005
GN   {ECO:0000313|EMBL:CAI34245.1}, SPC35A_0005
GN   {ECO:0000313|EMBL:CAI34281.1}, SPC35B_0005
GN   {ECO:0000313|EMBL:CAI34305.1}, SPC35C_0005
GN   {ECO:0000313|EMBL:CAI34323.1};
OS   Streptococcus pneumoniae.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1313 {ECO:0000313|EMBL:CAA07395.1};
RN   [1] {ECO:0000313|EMBL:CAA07395.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=SSISP 33F Type 33F {ECO:0000313|EMBL:CAA07395.1};
RX   PubMed=9838125; DOI=10.1016/S0167-4781(98)00213-9;
RA   Llull D., Lopez R., Garcia E., Munoz R.;
RT   "Molecular structure of the gene cluster responsible for the synthesis
RT   of the polysaccharide capsule of Streptococcus pneumoniae type 33F.";
RL   Biochim. Biophys. Acta 1443:217-224(1998).
RN   [2] {ECO:0000313|EMBL:CAI33504.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=1936/39 {ECO:0000313|EMBL:CAI34281.1}, 3084/37
RC   {ECO:0000313|EMBL:CAI34245.1}, 4356/39 {ECO:0000313|EMBL:CAI34305.1},
RC   7098/41 {ECO:0000313|EMBL:CAI34208.1}, 7765/43
RC   {ECO:0000313|EMBL:CAI34323.1}, Biehl {ECO:0000313|EMBL:CAI34168.1},
RC   and Rose {ECO:0000313|EMBL:CAI33504.1};
RX   PubMed=16532061; DOI=10.1371/journal.pgen.0020031;
RA   Bentley S.D., Aanensen D.M., Mavroidi A., Saunders D.,
RA   Rabbinowitsch E., Collins M., Donohoe K., Harris D., Murphy L.,
RA   Quail M.A., Samuel G., Skovsted I.C., Kaltoft M.S., Barrell B.,
RA   Reeves P.R., Parkhill J., Spratt B.G.;
RT   "Genetic analysis of the capsular biosynthetic locus from all 90
RT   pneumococcal serotypes.";
RL   PLoS Genet. 2:262-268(2006).
RN   [3] {ECO:0000313|EMBL:AEV23243.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=29OP8Nov {ECO:0000313|EMBL:AEV23243.1}, H0 6092 0119
RC   {ECO:0000313|EMBL:AEY99908.1}, H0 8334 0064
RC   {ECO:0000313|EMBL:AEY99909.1}, H0 9084 0082
RC   {ECO:0000313|EMBL:AEY99911.1}, SG24b {ECO:0000313|EMBL:AEY99872.1},
RC   SG24f {ECO:0000313|EMBL:AEY99873.1}, SG33c
RC   {ECO:0000313|EMBL:AEY99880.1}, SG33d {ECO:0000313|EMBL:AEY99881.1},
RC   SG35a {ECO:0000313|EMBL:AEY99884.1}, and SG35b
RC   {ECO:0000313|EMBL:AEY99885.1};
RA   Leung M.H.Y.;
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:AEY99926.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=55OP3 {ECO:0000313|EMBL:AEY99926.1};
RA   Leung M.;
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN   [5] {ECO:0000313|EMBL:AEV23243.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=29OP8Nov {ECO:0000313|EMBL:AEV23243.1}, 55OP3
RC   {ECO:0000313|EMBL:AEY99926.1}, H0 6092 0119
RC   {ECO:0000313|EMBL:AEY99908.1}, H0 8334 0064
RC   {ECO:0000313|EMBL:AEY99909.1}, H0 9084 0082
RC   {ECO:0000313|EMBL:AEY99911.1}, SG24b {ECO:0000313|EMBL:AEY99872.1},
RC   SG24f {ECO:0000313|EMBL:AEY99873.1}, SG33c
RC   {ECO:0000313|EMBL:AEY99880.1}, SG33d {ECO:0000313|EMBL:AEY99881.1},
RC   SG35a {ECO:0000313|EMBL:AEY99884.1}, and SG35b
RC   {ECO:0000313|EMBL:AEY99885.1};
RX   PubMed=22553238; DOI=10.1128/JCM.06384-11;
RA   Leung M.H., Bryson K., Freystatter K., Pichon B., Edwards G.,
RA   Charalambous B.M., Gillespie S.H.;
RT   "Sequetyping: Serotyping Streptococcus pneumoniae by a Single PCR
RT   Sequencing Strategy.";
RL   J. Clin. Microbiol. 50:2419-2427(2012).
RN   [6] {ECO:0000313|EMBL:CEV40578.1, ECO:0000313|Proteomes:UP000040760, ECO:0000313|Proteomes:UP000047500}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1 {ECO:0000313|EMBL:COM84528.1,
RC   ECO:0000313|Proteomes:UP000040760}, SMRU1004
RC   {ECO:0000313|EMBL:CEV40578.1, ECO:0000313|Proteomes:UP000047500},
RC   SMRU1012 {ECO:0000313|EMBL:COE69210.1}, and SMRU1013
RC   {ECO:0000313|EMBL:COE95193.1};
RA   Murphy D.;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [7] {ECO:0000313|EMBL:CTL53763.1, ECO:0000313|Proteomes:UP000042315}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R34-3139 {ECO:0000313|EMBL:CTL53763.1,
RC   ECO:0000313|Proteomes:UP000042315};
RA   Informatics Pathogen;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; JN642328; AEV23243.1; -; Genomic_DNA.
DR   EMBL; JN660101; AEY99872.1; -; Genomic_DNA.
DR   EMBL; JN660102; AEY99873.1; -; Genomic_DNA.
DR   EMBL; JN660109; AEY99880.1; -; Genomic_DNA.
DR   EMBL; JN660110; AEY99881.1; -; Genomic_DNA.
DR   EMBL; JN660113; AEY99884.1; -; Genomic_DNA.
DR   EMBL; JN660114; AEY99885.1; -; Genomic_DNA.
DR   EMBL; JN660137; AEY99908.1; -; Genomic_DNA.
DR   EMBL; JN660138; AEY99909.1; -; Genomic_DNA.
DR   EMBL; JN660140; AEY99911.1; -; Genomic_DNA.
DR   EMBL; JQ009437; AEY99926.1; -; Genomic_DNA.
DR   EMBL; AJ006986; CAA07395.1; -; Genomic_DNA.
DR   EMBL; CR931670; CAI33504.1; -; Genomic_DNA.
DR   EMBL; CR931698; CAI34168.1; -; Genomic_DNA.
DR   EMBL; CR931700; CAI34208.1; -; Genomic_DNA.
DR   EMBL; CR931702; CAI34245.1; -; Genomic_DNA.
DR   EMBL; CR931704; CAI34281.1; -; Genomic_DNA.
DR   EMBL; CR931705; CAI34305.1; -; Genomic_DNA.
DR   EMBL; CR931706; CAI34323.1; -; Genomic_DNA.
DR   EMBL; CFAX01000015; CEV40578.1; -; Genomic_DNA.
DR   EMBL; CRCH01000036; COE69210.1; -; Genomic_DNA.
DR   EMBL; CRCO01000040; COE95193.1; -; Genomic_DNA.
DR   EMBL; CRPE01000001; COM84528.1; -; Genomic_DNA.
DR   EMBL; CNXR02000089; CTL53763.1; -; Genomic_DNA.
DR   RefSeq; WP_000565372.1; NZ_FHSL01000011.1.
DR   STRING; 170187.SpneT_02000819; -.
DR   EnsemblBacteria; CTK80131; CTK80131; ERS044039_00440.
DR   EnsemblBacteria; CTK86240; CTK86240; ERS069978_00270.
DR   EnsemblBacteria; CTK88265; CTK88265; ERS069965_00388.
DR   EnsemblBacteria; CTK95900; CTK95900; ERS044055_00434.
DR   EnsemblBacteria; CTK96068; CTK96068; ERS070070_00388.
DR   EnsemblBacteria; CTK97016; CTK97016; ERS069926_00435.
DR   EnsemblBacteria; CTL01508; CTL01508; ERS070025_00364.
DR   EnsemblBacteria; CTL05414; CTL05414; ERS070064_00434.
DR   EnsemblBacteria; CTL05531; CTL05531; ERS070010_00363.
DR   EnsemblBacteria; CTL06330; CTL06330; ERS070034_00390.
DR   EnsemblBacteria; CTL06497; CTL06497; ERS069977_00365.
DR   EnsemblBacteria; CTL09113; CTL09113; ERS044140_00359.
DR   EnsemblBacteria; CTL09233; CTL09233; ERS070141_00393.
DR   EnsemblBacteria; CTL09426; CTL09426; ERS070091_00363.
DR   EnsemblBacteria; CTL12645; CTL12645; ERS043864_00431.
DR   EnsemblBacteria; CTL16803; CTL16803; ERS043906_00386.
DR   EnsemblBacteria; CTL19416; CTL19416; ERS070054_00390.
DR   EnsemblBacteria; CTL19432; CTL19432; ERS069995_00368.
DR   EnsemblBacteria; CTL21606; CTL21606; ERS069980_00365.
DR   EnsemblBacteria; CTL24592; CTL24592; ERS043888_00387.
DR   EnsemblBacteria; CTL26918; CTL26918; ERS043902_00386.
DR   EnsemblBacteria; CTL31500; CTL31500; ERS070127_00362.
DR   EnsemblBacteria; CTL31690; CTL31690; ERS070207_00437.
DR   EnsemblBacteria; CTL38007; CTL38007; ERS043846_00358.
DR   EnsemblBacteria; CTL41882; CTL41882; ERS070039_00360.
DR   EnsemblBacteria; CTL44260; CTL44260; ERS070132_00361.
DR   EnsemblBacteria; CTL44463; CTL44463; ERS043933_00432.
DR   EnsemblBacteria; CTL48797; CTL48797; ERS043943_00348.
DR   EnsemblBacteria; CTL48914; CTL48914; ERS043968_00387.
DR   EnsemblBacteria; CTL51467; CTL51467; ERS043969_00443.
DR   EnsemblBacteria; CTL52144; CTL52144; ERS043893_00358.
DR   EnsemblBacteria; CTL52426; CTL52426; ERS070168_00362.
DR   EnsemblBacteria; CTL53763; CTL53763; ERS043947_00361.
DR   EnsemblBacteria; CTL57147; CTL57147; ERS070164_00367.
DR   EnsemblBacteria; CTL59361; CTL59361; ERS070170_00363.
DR   EnsemblBacteria; CTL60099; CTL60099; ERS044009_00271.
DR   EnsemblBacteria; CTL61584; CTL61584; ERS044034_00383.
DR   EnsemblBacteria; CTL65133; CTL65133; ERS043976_00358.
DR   EnsemblBacteria; CTL69815; CTL69815; ERS070181_00366.
DR   EnsemblBacteria; CTL69930; CTL69930; ERS044032_00359.
DR   EnsemblBacteria; CTL72231; CTL72231; ERS070192_00358.
DR   EnsemblBacteria; CTL73013; CTL73013; ERS070184_00359.
DR   EnsemblBacteria; CTL77471; CTL77471; ERS043916_00357.
DR   EnsemblBacteria; CTL78190; CTL78190; ERS070190_00361.
DR   EnsemblBacteria; CTL96977; CTL96977; ERS070166_00368.
DR   EnsemblBacteria; CTN71730; CTN71730; ERS070143_00495.
DR   EnsemblBacteria; CTN80458; CTN80458; ERS070149_02449.
DR   EnsemblBacteria; CTN83351; CTN83351; ERS070197_02325.
DR   EnsemblBacteria; CTN84986; CTN84986; ERS070109_00117.
DR   EnsemblBacteria; CTO10823; CTO10823; ERS043876_00083.
DR   EnsemblBacteria; CTO59440; CTO59440; ERS043978_01943.
DR   EnsemblBacteria; CTO60329; CTO60329; ERS070076_02210.
DR   EnsemblBacteria; CTO80515; CTO80515; ERS070148_00139.
DR   EnsemblBacteria; CTO90183; CTO90183; ERS043935_00420.
DR   EnsemblBacteria; CTO92719; CTO92719; ERS044028_00507.
DR   EnsemblBacteria; CTO96485; CTO96485; ERS043936_00506.
DR   EnsemblBacteria; CTP09482; CTP09482; ERS043844_00504.
DR   EnsemblBacteria; CTP69604; CTP69604; ERS044095_02056.
DR   eggNOG; ENOG4108RB3; Bacteria.
DR   eggNOG; COG4464; LUCA.
DR   Proteomes; UP000040760; Unassembled WGS sequence.
DR   Proteomes; UP000042315; Unassembled WGS sequence.
DR   Proteomes; UP000047500; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   InterPro; IPR016667; Caps_polysacc_synth_CpsB/CapC.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PIRSF; PIRSF016557; Caps_synth_CpsB; 1.
DR   SUPFAM; SSF51556; SSF51556; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000040760,
KW   ECO:0000313|Proteomes:UP000042315, ECO:0000313|Proteomes:UP000047500};
KW   Hydrolase {ECO:0000313|EMBL:CAI33504.1};
KW   Kinase {ECO:0000313|EMBL:AEY99926.1};
KW   Transferase {ECO:0000313|EMBL:AEY99926.1}.
SQ   SEQUENCE   243 AA;  28200 MW;  364CEE24E94A5FE2 CRC64;
     MIDIHSHIVF DVDDGPKSRE ESKALLTESY RQGVRTIVST SHRRKGMFET PEEKIAENFL
     QVREIAKEVA SDLVIAYGAE IYYTPDVLDK LEKKRIPTLN DSRYALIEFS MNTPYRDIHS
     ALSKILMLGI TPVIAHIERY DALENNEKRV RELIDRGCYT QVNSSHVLKP KLFGERYKFM
     KKRAQYFLEQ DLVHIIASDM HNLDGRPPHM AEAYDLVTQK YGEAKAQELF IDNPRKIVMD
     QLI
//