ID CYB_SORTR STANDARD; PRT; 336 AA. AC O79465; O79466; DT 15-JUL-1999 (Rel. 38, Created) DT 15-JUL-1999 (Rel. 38, Last sequence update) DT 15-JUL-1999 (Rel. 38, Last annotation update) DE CYTOCHROME B (FRAGMENT). GN MTCYB OR COB OR CYTB. OS Sorex trowbridgii. OG Mitochondrion. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia; OC Eutheria; Insectivora; Soricidae; Sorex. RN [1] RP SEQUENCE FROM N.A. RA FUMAGALLI L., TABERLET P., STEWART D.T., GIELLY L., HAUSSER J., RA VOGEL P.; RT "Molecular phylogeny and evolution of Sorex shrews (Soricidae: RT Insectivora) inferred from mitochondrial DNA sequence data."; RL Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: COMPONENT OF THE UBIQUINOL-CYTOCHROME C REDUCTASE CC COMPLEX (COMPLEX III OR CYTOCHROME B-C1 COMPLEX), WHICH IS A CC RESPIRATORY CHAIN THAT GENERATES AN ELECTROCHEMICAL POTENTIAL CC COUPLED TO ATP SYNTHESIS. CC -!- CATALYTIC ACTIVITY: QH(2) + 2 FERRICYTOCHROME C = Q + CC 2 FERROCYTOCHROME C. CC -!- COFACTOR: TWO HEME GROUPS (B562 AND B566) WHICH ARE NOT COVALENTLY CC BOUND TO THE PROTEIN. CC -!- SUBUNIT: THE MAIN SUBUNITS OF COMPLEX B-C1 ARE: CYTOCHROME B, CC CYTOCHROME C1 AND THE RIESKE PROTEIN. CC -!- SIMILARITY: BELONGS TO THE CYTOCHROME B FAMILY. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJ000463; CAA04106.1; -. DR EMBL; AJ000464; CAA04107.1; -. DR PFAM; PF00032; cytochrome_b_C; 1. DR PFAM; PF00033; cytochrome_b_N; 1. DR PROSITE; PS00192; CYTOCHROME_B_HEME; 1. DR PROSITE; PS00193; CYTOCHROME_B_QO; 1. KW Mitochondrion; Electron transport; Respiratory chain; Transmembrane; KW Heme. FT NON_TER 1 1 FT METAL 40 40 IRON 1 (HEME B562 AXIAL LIGAND). FT METAL 54 54 IRON 2 (HEME B566 AXIAL LIGAND). FT METAL 139 139 IRON 2 (HEME B562 AXIAL LIGAND). FT METAL 153 153 IRON 1 (HEME B566 AXIAL LIGAND). FT VARIANT 219 219 L -> H. FT VARIANT 233 233 F -> L. FT VARIANT 249 249 L -> M. FT VARIANT 305 305 I -> T. FT VARIANT 310 310 M -> L. FT NON_TER 336 336 SQ SEQUENCE 336 AA; 37861 MW; 607C4342 CRC32; QILTGLFLAM HYTSDTLTAF SSVTHICRDV NYGWLIRYMH ANGASMFFIC LFMHVGRGIY YGSYMFLETW NIGVLLLFAV MATAFMGYVL PWGQMSFWGA TVITNLLSAI PYIGTDLVEW IWGGFSVDKA TLTRFFAFHF ILPFIIAALA GVHLLFLHET GSNNPSGLSS DADKIPFHPY YTIKDILGVL LFILVLTSLV LFSPDLLGDP DNYTPANPLN TPPHIKPEWY FLFAYAILRS IPNKLGGVLA LVLSILVLAV IPFLHTSKQR SMMFRPLSQC LFWILVADLL TLTWIGGQPV EHPFIIIGQM ASILYFLLIL VLMPITSLFE NNLLKW //