ID O77240_CHOFU Unreviewed; 513 AA. AC O77240; DT 01-NOV-1998, integrated into UniProtKB/TrEMBL. DT 01-MAY-2000, sequence version 2. DT 16-SEP-2015, entry version 82. DE SubName: Full=Ecdysone receptor isoform A {ECO:0000313|EMBL:AAC61596.2}; GN Name=EcR {ECO:0000313|EMBL:AAC61596.2}; OS Choristoneura fumiferana (Spruce budworm moth) (Archips fumiferana). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; OC Tortricoidea; Tortricidae; Tortricinae; Choristoneura. OX NCBI_TaxID=7141 {ECO:0000313|EMBL:AAC61596.2}; RN [1] {ECO:0000313|EMBL:AAC61596.2} RP NUCLEOTIDE SEQUENCE. RX PubMed=10432225; DOI=10.1016/S0303-7207(99)00058-1; RA Perera S.C., Ladd T.R., Dhadialla T.S., Krell P.J., Sohi S.S., RA Retnakaran A., Palli S.R.; RT "Studies on two ecdysone receptor isoforms of the spruce budworm, RT Choristoneura fumiferana."; RL Mol. Cell. Endocrinol. 152:73-84(1999). CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family. CC {ECO:0000256|RuleBase:RU000377}. CC -!- SIMILARITY: Contains nuclear receptor DNA-binding domain. CC {ECO:0000256|SAAS:SAAS00116555}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF092030; AAC61596.2; -; mRNA. DR ProteinModelPortal; O77240; -. DR BindingDB; O77240; -. DR ChEMBL; CHEMBL2366580; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW. DR GO; GO:0004884; F:ecdysteroid hormone receptor activity; IEA:InterPro. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0005496; F:steroid binding; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW. DR Gene3D; 1.10.565.10; -; 2. DR Gene3D; 3.30.50.10; -; 1. DR InterPro; IPR003069; Ecdystd_rcpt. DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd. DR InterPro; IPR001723; Nuclear_hrmn_rcpt. DR InterPro; IPR001628; Znf_hrmn_rcpt. DR InterPro; IPR013088; Znf_NHR/GATA. DR Pfam; PF00104; Hormone_recep; 1. DR Pfam; PF00105; zf-C4; 1. DR PRINTS; PR01283; ECDYSTEROIDR. DR PRINTS; PR00398; STRDHORMONER. DR PRINTS; PR00047; STROIDFINGER. DR SMART; SM00430; HOLI; 1. DR SMART; SM00399; ZnF_C4; 1. DR SUPFAM; SSF48508; SSF48508; 1. DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1. DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1. PE 2: Evidence at transcript level; KW DNA-binding {ECO:0000256|RuleBase:RU004334, KW ECO:0000256|SAAS:SAAS00116462}; KW Metal-binding {ECO:0000256|RuleBase:RU004334, KW ECO:0000256|SAAS:SAAS00116612}; KW Nucleus {ECO:0000256|RuleBase:RU004334, KW ECO:0000256|SAAS:SAAS00306265}; KW Receptor {ECO:0000256|RuleBase:RU004334, ECO:0000313|EMBL:AAC61596.2}; KW Transcription {ECO:0000256|RuleBase:RU004334, KW ECO:0000256|SAAS:SAAS00306222}; KW Transcription regulation {ECO:0000256|RuleBase:RU004334, KW ECO:0000256|SAAS:SAAS00306243}; KW Zinc {ECO:0000256|RuleBase:RU004334, ECO:0000256|SAAS:SAAS00116516}; KW Zinc-finger {ECO:0000256|RuleBase:RU004334, KW ECO:0000256|SAAS:SAAS00116578}. SQ SEQUENCE 513 AA; 57622 MW; F110540A3030E602 CRC64; MDLKHEVAYR GVLPGQVKAE PGVHNGQVNG HVRDWMAGGA GANSPSPGAV AQPQPNNGYS SPLSSGSYGP YSPNGKIGRE ELSPASSING CSTDGEARRQ KKGPAPRQQE ELCLVCGDRA SGYHYNALTC EGCKGFFRRS VTKNAVYICK FGHACEMDMY MRRKCQECRL KKCLAVGMRP ECVVPETQCA MKRKEKKAQK EKDKLPVSTT TVDDHMPPIM QCEPPPPEAA RIHEVVPRFL SDKLLETNRQ KNIPQLTANQ QFLIARLIWY QDGYEQPSDE DLKRITQTWQ QADDENEESD TPFRQITEMT ILTVQLIVEF AKGLPGFAKI SQPDQITLLK ACSSEVMMLR VARRYDAASD SVLFANNQAY TRDNYRKAGM AYVIEDLLHF CRCMYSMALD NIHYALLTAV VIFSDRPGLE QPQLVEEIQR YYLNTLRIYI LNQLSGSARS SVIYGKILSI LSELRTLGMQ NSNMCISLKL KNRKLPPFLE EIWDVADMSH TQPPPILESP TNL //