ID O76268_DROME Unreviewed; 461 AA. AC O76268; DT 01-NOV-1998, integrated into UniProtKB/TrEMBL. DT 01-NOV-1998, sequence version 1. DT 08-FEB-2011, entry version 69. DE SubName: Full=LD11641p; DE SubName: Full=NTPDase 6; DE SubName: Full=NTPase; DE SubName: Full=NTPase, isoform A; DE EC=3.6.1.15; DE EC=3.6.1.42; DE EC=3.6.1.6; GN Name=NTPase; ORFNames=CG3059, Dmel_CG3059; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX MEDLINE=20196006; PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., RA Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., RA Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., RA Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] RP GLYCOSYLATION [LARGE SCALE ANALYSIS], AND MASS SPECTROMETRY. RX PubMed=17893096; DOI=10.1093/glycob/cwm097; RA Koles K., Lim J.-M., Aoki K., Porterfield M., Tiemeyer M., Wells L., RA Panin V.; RT "Identification of N-glycosylated proteins from the central nervous RT system of Drosophila melanogaster."; RL Glycobiology 17:1388-1403(2007). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX MEDLINE=22426069; PubMed=12537572; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [4] RP NUCLEOTIDE SEQUENCE. RA Knowles A.F.; RT "The single NTPase gene of Drosophila melanogaster encodes an RT intracellular nucleoside triphosphate diphosphohydrolase 6 RT (NTPDase6)."; RL Arch. Biochem. Biophys. 484:70-79(2009). RN [5] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Berkeley; RA Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., RA Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R., RA Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J., RA Nunoo J., Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K., RA Yu C., Lewis S.E., Rubin G.M., Celniker S.; RL Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases. RN [6] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=98341119; PubMed=9676430; DOI=10.1006/geno.1998.5317; RA Chadwick B.P., Frischauf A.-M.; RT "The CD39-like gene family: identification of three new human members RT (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of RT the gene family from Drosophila melanogaster."; RL Genomics 50:357-367(1998). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF041048; AAC39133.1; -; Genomic_DNA. DR EMBL; AE014134; AAF51182.1; -; Genomic_DNA. DR EMBL; AY061134; AAL28682.1; -; mRNA. DR EMBL; EU852293; ACF58165.1; -; mRNA. DR RefSeq; NP_477370.1; NM_058022.3. DR UniGene; Dm.7259; -. DR ProteinModelPortal; O76268; -. DR SMR; O76268; 78-451. DR STRING; O76268; -. DR PRIDE; O76268; -. DR EnsemblMetazoa; FBtr0077683; FBpp0077367; FBgn0024947. DR GeneID; 33495; -. DR KEGG; dme:Dmel_CG3059; -. DR UCSC; CG3059-RA; d. melanogaster. DR CTD; 33495; -. DR FlyBase; FBgn0024947; NTPase. DR eggNOG; inNOG08946; -. DR InParanoid; O76268; -. DR PhylomeDB; O76268; -. DR NextBio; 783870; -. DR ArrayExpress; O76268; -. DR Bgee; O76268; -. DR GO; GO:0005737; C:cytoplasm; IDA:FlyBase. DR GO; GO:0004382; F:guanosine-diphosphatase activity; IDA:FlyBase. DR GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:EC. DR GO; GO:0045134; F:uridine-diphosphatase activity; IDA:FlyBase. DR InterPro; IPR000407; GDA1_CD39_NTPase. DR PANTHER; PTHR11782; GDA1_CD39_NTPase; 1. DR Pfam; PF01150; GDA1_CD39; 1. PE 1: Evidence at protein level; KW Complete proteome; Hydrolase. SQ SEQUENCE 461 AA; 50845 MW; 27D00321F91A9DD1 CRC64; MKYEYKLLAT DEKPPRRKSS GSPNASSGGN RGPSGLKISF LCLIISVILL LFVFGFVSEN ASPYLARLAS KFGYSKVQYA AIIDAGSTGS RVLAYKFNRS FIDNKLVLYE ELFKERKPGL SSFADNPAEG AHSIKLLLDE ARAFIPKEHW SSTPLVLKAT AGLRLLPASK AENILNAVRD LFAKSEFSVD MDAVEIMDGT DEGIFSWFTV NFLLGRLSKT NQAAALDLGG GSTQVTFSPT DPDQVPVYDK YMHEVVTSSK KINVFTHSYL GLGLMAARHA VFTHGYKKED TVLESVCVNP IIANRTWTYG NVQYKVSGKE NGKSSAEQPI VDFDACLELV KSKVMPLVKP KPFTLKQHAV AAFSYYFERA IESGLVDPLA GGETTVEAYR KKAQEICAIP NDEQPFMCFD LTFISTLLRE GFGLNDGKKI KLYKKIDGHE ISWALGCAYN VLTSDEKFSN S //