ID NIPS2_HUMAN Reviewed; 286 AA. AC O75323; O43801; DT 26-SEP-2001, integrated into UniProtKB/Swiss-Prot. DT 01-NOV-1998, sequence version 1. DT 04-NOV-2008, entry version 59. DE RecName: Full=Protein NipSnap homolog 2; DE Short=NipSnap2; DE AltName: Full=Glioblastoma-amplified sequence; GN Name=GBAS; Synonyms=NIPSNAP2; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RX MEDLINE=98277458; PubMed=9615231; DOI=10.1006/geno.1998.5239; RA Wang X.-Y., Smith D.I., Liu W., James C.D.; RT "GBAS, a novel gene encoding a protein with tyrosine phosphorylation RT sites and a transmembrane domain, is co-amplified with EGFR."; RL Genomics 49:448-451(1998). RN [2] RP NUCLEOTIDE SEQUENCE [MRNA]. RX MEDLINE=98326305; PubMed=9661659; DOI=10.1016/S0378-1119(98)00098-5; RA Seroussi E., Pan H.Q., Kedra D., Roe B.A., Dumanski J.P.; RT "Characterization of the human NIPSNAP1 gene from 22q12: a member of a RT novel gene family."; RL Gene 212:13-20(1998). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RA Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., RA Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., RA Phelan M., Farmer A.; RT "Cloning of human full-length CDSs in BD Creator(TM) system donor RT vector."; RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Colon, and Lung; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC -!- TISSUE SPECIFICITY: Widely expressed. Most abundant in heart and CC skeletal muscle. CC -!- SIMILARITY: Belongs to the NipSnap family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF029786; AAC29002.1; -; mRNA. DR EMBL; AJ001259; CAA04633.1; -; mRNA. DR EMBL; BT007112; AAP35776.1; -; mRNA. DR EMBL; BC000732; AAH00732.1; -; mRNA. DR EMBL; BC001837; AAH01837.1; -; mRNA. DR EMBL; BC030821; AAH30821.1; -; mRNA. DR RefSeq; NP_001474.1; -. DR UniGene; Hs.591069; -. DR IntAct; O75323; -. DR PeptideAtlas; O75323; -. DR Ensembl; ENSG00000146729; Homo sapiens. DR GeneID; 2631; -. DR KEGG; hsa:2631; -. DR HGNC; HGNC:4179; GBAS. DR MIM; 603004; gene. DR PharmGKB; PA28593; -. DR HOGENOM; O75323; -. DR HOVERGEN; O75323; -. DR LinkHub; O75323; -. DR NextBio; 10372; -. DR ArrayExpress; O75323; -. DR CleanEx; HS_GBAS; -. DR GermOnline; ENSG00000146729; Homo sapiens. DR GO; GO:0005887; C:integral to plasma membrane; TAS:ProtInc. DR GO; GO:0005624; C:membrane fraction; TAS:ProtInc. DR GO; GO:0005739; C:mitochondrion; ISS:UniProtKB. DR InterPro; IPR012577; NIPSNAP. DR Pfam; PF07978; NIPSNAP; 1. PE 1: Evidence at protein level; FT CHAIN 1 286 Protein NipSnap homolog 2. FT /FTId=PRO_0000221148. FT CONFLICT 9 16 RGAAWAGG -> AEALGRR (in Ref. 2; FT CAA04633). SQ SEQUENCE 286 AA; 33743 MW; 7ED85297E4DC9D08 CRC64; MAARVLRARG AAWAGGLLQR AAPCSLLPRL RTWTSSSNRS REDSWLKSLF VRKVDPRKDA HSNLLAKKET SNLYKLQFHN VKPECLEAYN KICQEVLPKI HEDKHYPCTL VGTWNTWYGE QDQAVHLWRY EGGYPALTEV MNKLRENKEF LEFRKARSDM LLSRKNQLLL EFSFWNEPVP RSGPNIYELR SYQLRPGTMI EWGNYWARAI RFRQDGNEAV GGFFSQIGQL YMVHHLWAYR DLQTREDIRN AAWHKHGWEE LVYYTVPLIQ EMESRIMIPL KTSPLQ //