ID NIPS2_HUMAN STANDARD; PRT; 286 AA. AC O75323; O43801; DT 26-SEP-2001, integrated into UniProtKB/Swiss-Prot. DT 01-NOV-1998, sequence version 1. DT 04-APR-2006, entry version 38. DE Protein NipSnap2 (Glioblastoma amplified sequence). GN Name=GBAS; Synonyms=NIPSNAP2; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RX MEDLINE=98277458; PubMed=9615231; DOI=10.1006/geno.1998.5239; RA Wang X.-Y., Smith D.I., Liu W., James C.D.; RT "GBAS, a novel gene encoding a protein with tyrosine phosphorylation RT sites and a transmembrane domain, is co-amplified with EGFR."; RL Genomics 49:448-451(1998). RN [2] RP NUCLEOTIDE SEQUENCE [MRNA]. RX MEDLINE=98326305; PubMed=9661659; DOI=10.1016/S0378-1119(98)00098-5; RA Seroussi E., Pan H.Q., Kedra D., Roe B.A., Dumanski J.P.; RT "Characterization of the human NIPSNAP1 gene from 22q12: a member of a RT novel gene family."; RL Gene 212:13-20(1998). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RA Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., RA Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., RA Phelan M., Farmer A.; RT "Cloning of human full-length CDSs in BD Creator(TM) system donor RT vector."; RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Colon, and Lung; RX MEDLINE=22388257; PubMed=12477932; DOI=10.1073/pnas.242603899; RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., RA Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., RA Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., RA Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., RA Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., RA Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., RA Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., RA Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., RA Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., RA Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., RA Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., RA Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., RA Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., RA Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., RA Butterfield Y.S.N., Krzywinski M.I., Skalska U., Smailus D.E., RA Schnerch A., Schein J.E., Jones S.J.M., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human RT and mouse cDNA sequences."; RL Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002). CC -!- TISSUE SPECIFICITY: Widely expressed. Most abundant in heart and CC skeletal muscle. CC -!- SIMILARITY: Belongs to the NipSnap family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF029786; AAC29002.1; -; mRNA. DR EMBL; AJ001259; CAA04633.1; -; mRNA. DR EMBL; BT007112; AAP35776.1; -; mRNA. DR EMBL; BC000732; AAH00732.1; -; mRNA. DR EMBL; BC001837; AAH01837.1; -; mRNA. DR EMBL; BC030821; AAH30821.1; -; mRNA. DR UniGene; Hs.437367; -. DR IntAct; O75323; -. DR Ensembl; ENSG00000146729; Homo sapiens. DR H-InvDB; HIX0006702; -. DR HGNC; HGNC:4179; GBAS. DR MIM; 603004; gene. DR GO; GO:0005887; C:integral to plasma membrane; TAS. DR GO; GO:0005624; C:membrane fraction; TAS. DR GO; GO:0005739; C:mitochondrion; ISS. DR InterPro; IPR012577; NIPSNAP. DR Pfam; PF07978; NIPSNAP; 1. FT CHAIN 1 286 Protein NipSnap2. FT /FTId=PRO_0000221148. FT CONFLICT 9 16 RGAAWAGG -> AEALGRR (in Ref. 2). SQ SEQUENCE 286 AA; 33743 MW; 7ED85297E4DC9D08 CRC64; MAARVLRARG AAWAGGLLQR AAPCSLLPRL RTWTSSSNRS REDSWLKSLF VRKVDPRKDA HSNLLAKKET SNLYKLQFHN VKPECLEAYN KICQEVLPKI HEDKHYPCTL VGTWNTWYGE QDQAVHLWRY EGGYPALTEV MNKLRENKEF LEFRKARSDM LLSRKNQLLL EFSFWNEPVP RSGPNIYELR SYQLRPGTMI EWGNYWARAI RFRQDGNEAV GGFFSQIGQL YMVHHLWAYR DLQTREDIRN AAWHKHGWEE LVYYTVPLIQ EMESRIMIPL KTSPLQ //