ID EFER_HUMAN STANDARD; PRT; 756 AA. AC O75154; Q9H155; Q9H1G0; Q9NUI0; DT 16-OCT-2001 (Rel. 40, Created) DT 16-OCT-2001 (Rel. 40, Last sequence update) DT 28-FEB-2003 (Rel. 41, Last annotation update) DE Eferin. GN KIAA0665. OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP SEQUENCE FROM N.A. RX MEDLINE=21486406; PubMed=11481332; RA Prekeris R., Davies J.M., Scheller R.H.; RT "Identification of a novel Rab11/25 binding domain present in eferin RT and rip proteins."; RL J. Biol. Chem. 276:38966-38970(2001). RN [2] RP SEQUENCE FROM N.A. RC TISSUE=Brain; RX MEDLINE=98403880; PubMed=9734811; RA Ishikawa K.-I., Nagase T., Suyama M., Miyajima N., Tanaka A., RA Kotani H., Nomura N., Ohara O.; RT "Prediction of the coding sequences of unidentified human genes. X. RT The complete sequences of 100 new cDNA clones from brain which can RT code for large proteins in vitro."; RL DNA Res. 5:169-176(1998). RN [3] RP SEQUENCE FROM N.A. RX MEDLINE=21096910; PubMed=11157797; RA Daniels R.J., Peden J.F., Lloyd C., Horsley S.W., Clark K., RA Tufarelli C., Kearney L., Buckle V.J., Doggett N.A., Flint J., RA Higgs D.R.; RT "Sequence, structure and pathology of the fully annotated terminal 2 RT Mb of the short arm of human chromosome 16."; RL Hum. Mol. Genet. 10:339-352(2001). RN [4] RP SEQUENCE FROM N.A. RA Wallis J., Lloyd C., Hall R.; RL Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases. CC -!- SUBUNIT: Binds to RAB11 and RAB25. CC -!- SIMILARITY: Contains 2 EF-hand calcium-binding domains. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF395731; AAL12940.1; -. DR EMBL; AB014565; BAA31640.1; -. DR EMBL; AE006463; AAK61232.1; -. DR EMBL; AL023881; CAB92745.1; -. DR EMBL; AL049542; CAC17519.1; -. DR EMBL; Z98882; CAC17523.1; -. DR GO; GO:0017137; F:RAB interactor activity; NAS. DR InterPro; IPR002048; EF-hand. DR Pfam; PF00036; efhand; 2. DR SMART; SM00054; EFh; 2. KW Calcium-binding; Repeat. FT CA_BIND 215 226 EF-HAND 1 (POTENTIAL). FT CA_BIND 247 258 EF-HAND 2 (POTENTIAL). SQ SEQUENCE 756 AA; 82439 MW; 264CEC399F28AFB9 CRC64; MASAPPASPP GSEPPGPDPE PGGPDGPGAA QLAPGPAELR LGAPVGGPDP QSPGLDEPAP GAAADGGARW SAGPAPGLEG GPRDPGPSAP PPRSGPRGQL ASPDAPGPGP RSEAPLPELD PLFSWTEEPE ECGPASCPES APFRLQGSSS SHRARGEVDV FSPFPAPTAG ELALEQGPGS PPQPSDLSQT HPLPSEPVGS QEDGPRLRAV FDALDGDGDG FVRIEDFIQF ATVYGAEQVK DLTKYLDPSG LGVISFEDFY QGITAIRNGD PDGQCYGGVA SAQDEEPLAC PDEFDDFVTY EANEVTDSAY MGSESTYSEC ETFTDEDTST LVHPELQPEG DADSAGGSAV PSECLDAMEE PDHGALLLLP GRPHPHGQSV ITVIGGEEHF EDYGEGSEAE LSPETLCNGQ LGCSDPAFLT PSPTKRLSSK KVARYLHQSG ALTMEALEDP SPELMEGPEE DIADKVVFLE RRVLELEKDT AATGEQHSRL RQENLQLVHR ANALEEQLKE QELRACEMVL EETRRQKELL CKMEREKSIE IENLQTRLQQ LDEENSELRS CTPCLKANIE RLEEEKQKLL DEIESLTLRL SEEQENKRRM GDRLSHERHQ FQRDKEATQE LIEDLRKQLE HLQLLKLEAE QRRGRSSSMG LQEYHSRARE SELEQEVRRL KQDNRNLKEQ NEELNGQIIT LSIQGAKSLF STAFSESLAA EISSVSRDEL MEAIQKQEEI NFRLQDYIDR IIVAIMETNP SILEVK //