ID DIA2_MOUSE STANDARD; PRT; 349 AA. AC O70566; DT 15-JUL-1999 (Rel. 38, Created) DT 15-JUL-1999 (Rel. 38, Last sequence update) DT 15-JUL-1999 (Rel. 38, Last annotation update) DE DIAPHANOUS PROTEIN HOMOLOG 2 (FRAGMENT). GN DIAPH2 OR DIAP2. OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=BALB/C; RX MEDLINE; 98163437. RA Bione S., Sala C., Manzini C., Arrigo G., Zuffardi O., Banfi S., RA Borsani G., Jonveaux P., Philippe C., Zuccotti M., Ballabio A., RA Toniolo D.; RT "A human homologue of the Drosophila melanogaster diaphanous gene is RT disrupted in a patient with premature ovarian failure: evidence for RT conserved function in oogenesis and implications for human RT sterility."; RL Am. J. Hum. Genet. 62:533-541(1998). CC -!- FUNCTION: MAY BE INVOLVED IN OOGENESIS. CC -!- DEVELOPMENTAL STAGE: EXPRESSED IN LIVER, HEART, KIDNEY, OVARY AND CC TESTIS, AT E16, P6 AND P16. CC -!- DOMAIN: CONTAINS 1 FORMIN HOMOLOGY 2 (FH2) DOMAIN. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Y15910; CAA75871.1; -. KW Coiled coil. FT NON_TER 1 1 FT DOMAIN 14 155 FH2. FT DOMAIN 158 181 COILED COIL (POTENTIAL). FT DOMAIN 250 301 COILED COIL (POTENTIAL). FT DOMAIN 286 289 POLY-LYS. SQ SEQUENCE 349 AA; 40557 MW; B79C15CEE0E4F758 CRC64; RDLPDQNALR ELAQLKSEYD DLCEPEQFGV VMSTVKMLRP RLTSILFKLT FEEHVNNIKP SIIAVTLACE ELKKSESFKR LLELILLVGN YMNSGSRNAQ SLGFKINFLC KIKDTKSADQ KSTLLHFLAE ICDEKYRDIL KFPDELEHVE SAGKVSAQIL KSNLVAMEQS ILHLEKNIKN FPPAESHHDK FVEKMMSFTQ NAREQYDKLS TMHSNMLKLY ESLGEYFIFD PNTVNMEEFF GDLNTFRTLF LEALKENHKR KEMEEKSRRA KLAKEKAEQE KLERQKKKKQ LIDINKEGDE TGVMDNLLEA LQSGAAFRDR RKRIPRNPDN RRPPLERSRS RHNGAMSSK //