ID RL7A_TAKRU Reviewed; 266 AA. AC O57592; DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot. DT 23-JAN-2007, sequence version 3. DT 24-JUL-2024, entry version 106. DE RecName: Full=Large ribosomal subunit protein eL8 {ECO:0000305}; DE AltName: Full=60S ribosomal protein L7a; DE AltName: Full=Surfeit locus protein 3; GN Name=rpl7a; Synonyms=surf3; OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu. OX NCBI_TaxID=31033; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX PubMed=9414319; DOI=10.1101/gr.7.12.1138; RA Armes N., Gilley J., Fried M.; RT "The comparative genomic structure and sequence of the surfeit gene RT homologs in the puffer fish Fugu rubripes and their association with CpG- RT rich islands."; RL Genome Res. 7:1138-1152(1997). CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a CC large ribonucleoprotein complex responsible for the synthesis of CC proteins in the cell. {ECO:0000250|UniProtKB:P62424}. CC -!- SUBUNIT: Component of the large ribosomal subunit. CC {ECO:0000250|UniProtKB:P62424}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P62424}. CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL8 family. CC {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Y15171; CAA75444.1; -; Genomic_DNA. DR PIR; T52089; T52089. DR RefSeq; XP_003965297.1; XM_003965248.2. DR AlphaFoldDB; O57592; -. DR SMR; O57592; -. DR STRING; 31033.ENSTRUP00000075237; -. DR GeneID; 101064977; -. DR KEGG; tru:101064977; -. DR CTD; 6130; -. DR eggNOG; KOG3166; Eukaryota. DR InParanoid; O57592; -. DR OrthoDB; 160374at2759; -. DR Proteomes; UP000005226; Unplaced. DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IEA:TreeGrafter. DR GO; GO:0003723; F:RNA binding; IEA:TreeGrafter. DR GO; GO:0000470; P:maturation of LSU-rRNA; IEA:TreeGrafter. DR Gene3D; 3.30.1330.30; -; 1. DR InterPro; IPR050257; eL8_RNA-proc_assembly. DR InterPro; IPR029064; Ribosomal_eL30-like_sf. DR InterPro; IPR001921; Ribosomal_eL8. DR InterPro; IPR004037; Ribosomal_eL8-like_CS. DR InterPro; IPR004038; Ribosomal_eL8/eL30/eS12/Gad45. DR InterPro; IPR018492; Ribosomal_eL8/Nhp2. DR PANTHER; PTHR23105:SF1; 60S RIBOSOMAL PROTEIN L7A; 1. DR PANTHER; PTHR23105; RIBOSOMAL PROTEIN L7AE FAMILY MEMBER; 1. DR Pfam; PF01248; Ribosomal_L7Ae; 1. DR PRINTS; PR00881; L7ARS6FAMILY. DR PRINTS; PR00882; RIBOSOMALL7A. DR SUPFAM; SSF55315; L30e-like; 1. DR PROSITE; PS01082; RIBOSOMAL_L7AE; 1. PE 3: Inferred from homology; KW Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein. FT INIT_MET 1 FT /note="Removed" FT /evidence="ECO:0000250" FT CHAIN 2..266 FT /note="Large ribosomal subunit protein eL8" FT /id="PRO_0000136752" FT REGION 1..28 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 105..134 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 105..126 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 266 AA; 30001 MW; 3C47DDEC2BCA6DF7 CRC64; MPKGKKAKGK KVAPAPSVAK KHEAKKVVNP LFEKRPKNFG IGQDIQPKRD LTRFVKWPRY IRLQRQRSIL YKRLKVPPAI NQFTQALDRQ TATQLFKLAH KYRPETKQEK KKRLLARAEQ KAAGKGDAPT KRPPVLRAGV NTITSLVENK KAQLVVIAHD VDPIELVIFL PALCRKMGVP YCIVKGKARL GRLVHRKTCT SVAFTQTNPE DKGALAKLVE AIKTNYNDRY EEIRRHWGGG ILGPKSTARI NKLEKAKAKE LATKLG //