ID O55095 PRELIMINARY; PRT; 688 AA. AC O55095; DT 01-JUN-1998 (TrEMBLrel. 06, Created) DT 01-JUN-1998 (TrEMBLrel. 06, Last sequence update) DT 01-MAR-2004 (TrEMBLrel. 26, Last annotation update) DE SFlt-1. GN Name=Flt1; Synonyms=soluble form Flt-1 protein; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=C57b; TISSUE=lung; RX MEDLINE=94068470; PubMed=8248162; RA kendall R., Thomas K.; RT "Inhibition of vascular endothelial cell growth factor activity by an RT endogenously encoded soluble receptor."; RL Proc. Natl. Acad. Sci. U.S.A. 90:10705-10709(1993). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=C57b; TISSUE=lung; RX MEDLINE=98201626; PubMed=9524283; RA Kondo K., Hiratuka S., Subbalakshmi E., Matsushime H., Shibuya M.; RT "Genomic organization of the flt-1 gene encoding for vascular RT endothelial growth factor (VEGF) receptor-1 suggests an intimate RT evolutionary relationship between the 7-Ig and the 5-Ig tyrosine RT kinase receptor."; RL Gene 208:297-305(1998). RN [3] RP SEQUENCE FROM N.A. RC STRAIN=C57b; TISSUE=lung; RX MEDLINE=93330572; PubMed=8393164; RA Finnerty H., Kelleher K., Morris G., Bean K., Merberg D., Kriz R., RA Morris J., Sookdeo H., Turner K., Wood C.; RT "Molecular cloning of murin FLT and FLT4."; RL Oncogene 8:2293-2298(1993). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; D88690; BAA24499.1; -. DR HSSP; P17948; 1QSV. DR MGD; MGI:95558; Flt1. DR GO; GO:0005524; F:ATP binding; IEA. DR GO; GO:0005021; F:vascular endothelial growth factor receptor...; IEA. DR GO; GO:0006468; P:protein amino acid phosphorylation; IEA. DR InterPro; IPR007110; Ig-like. DR InterPro; IPR003598; Ig_c2. DR InterPro; IPR009134; VEGFR. DR InterPro; IPR009135; VEGFR1. DR Pfam; PF00047; ig; 3. DR PRINTS; PR01832; VEGFRECEPTOR. DR PRINTS; PR01833; VEGFRECEPTR1. DR SMART; SM00408; IGc2; 1. DR PROSITE; PS50835; IG_LIKE; 4. SQ SEQUENCE 688 AA; 77521 MW; 0301825F7F961A99 CRC64; MVSCWDTAVL PYALLGCLLL TGYGSGSKLK VPELSLKGTQ HVMQAGQTLF LKCRGEAAHS WSLPTTVSQE DKRLSITPPS ACGRDNRQFC STLTLDTAQA NHTGLYTCRY LPTSTSKKKK AESSIYIFVS DAGSPFIEMH TDIPKLVHMT EGRQLIIPCR VTSPNVTVTL KKFPFDTLTP DGQRITWDSR RGFIIANATY KEIGLLNCEA TVNGHLYQTN YLTHRQTNTI LDVQIRPPSP VRLLHGQTLV LNCTATTELN TRVQMSWNYP GKATKRASIR QRIDRSHSHN NVFHSVLKIN NVESRDKGLY TCRVKSGSSF QSFNTSVHVY EKGFISVKHR KQPVQETTAG RRSYRLSMKV KAFPSPEIVW LKDGSPATLK SARYLVHGYS LIIKDVTTED AGDYTILLGI KQSRLFKNLT ATLIVNVKPQ IYEKSVSSLP SPPLYPLGSR QVLTCTVYGI PRPTITWLWH PCHHNHSKER YDFCTENEES FILDPSSNLG NRIESISQRM TVIEGTNKTV STLVVADSQT PGIYSCRAFN KIGTVERNIK FYVTDVPNGF HVSLEKMPAE GEDLKLSCVV NKFLYRDITW ILLRTVNNRT MHHSISKQKM ATTQDYSITL NLVIKNVSLE DSGTYACRAR NIYTGEDILR KTEVLVRGEH CGKKAIFSRI SKFKSRRNDC TTQSHVKH //