ID O44940 PRELIMINARY; PRT; 606 AA. AC O44940; O46104; DT 01-JUN-1998 (TrEMBLrel. 06, Created) DT 01-JUN-1998 (TrEMBLrel. 06, Last sequence update) DT 01-MAY-2000 (TrEMBLrel. 13, Last annotation update) DE PPK PROTEIN (MULTIDENDRITIC NEURONS SODIUM CHANNEL 1). GN PPK OR MDNAC1. OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Tracheata; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=7227; RN [1] RP SEQUENCE FROM N.A. RX MEDLINE=98262943; PubMed=9600094; RA Darboux I., Lingueglia E., Pauron D., Barbry P., Lazdunski M.; RT "A new member of the amiloride-sensitive sodium channel family in RT Drosophila melanogaster peripheral nervous system."; RL Biochem. Biophys. Res. Commun. 246:210-216(1998). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=CANTON-S; RX MEDLINE=98087599; PubMed=9425162; RA Adams C.M., Anderson M.G., Motto D.G., Price M.P., Johnson W.A., RA Welsh M.J.; RT "Ripped pocket and pickpocket, novel Drosophila DEG/ENaC subunits RT expressed in early development and in mechanosensory neurons."; RL J. Cell Biol. 140:143-152(1998). RN [3] RP SEQUENCE FROM N.A. RC STRAIN=BERKELEY; RX MEDLINE=99403001; PubMed=10471707; RA Ashburner M., Misra S., Roote J., Lewis S.E., Blazej R., Davis T., RA Doyle C., Galle R., George R., Harris N., Hartzell G., Harvey D., RA Hong L., Houston K., Hoskins R., Johnson G., Martin C., Moshrefi A., RA Palazzolo M., Reese M.G., Spradling A., Tsang G., Wan K., Whitelaw K., RA Celniker S., Rubin G.M.; RT "An exploration of the sequence of a 2.9-Mb region of the genome of RT Drosophila melanogaster: the Adh region."; RL Genetics 153:179-219(1999). RN [4] RP SEQUENCE FROM N.A. RC STRAIN=BERKELEY; RA Celniker S.E., Agbayani A., Arcaina T.T., Baxter E., Blazej R.G., RA Butenhoff C., Champe M., Chavez C., Chew M., Ciesiolka L., Doyle C.M., RA Farfan D.E., Galle R., George R.A., Harris N.L., Hoskins R.A., RA Houston K.A., Hummasti S.R., Karra K., Kearney L., Kim E., Lee B., RA Lewis S., Li P., Lomotan M.A., Mazda P., Moshrefi A.R., Moshrefi M., RA Nixon K., Pacleb J.M., Park S., Pfeiffer B., Poon L., Sequeira A., RA Sethi H., Snir E., Svirskas R.R., Wan K.H., Weinburg T., Zhang R., RA Zieran L.L., Rubin G.M.; RL Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases. RN [5] RP SEQUENCE FROM N.A. RC STRAIN=BERKELEY; RX MEDLINE=20196006; PubMed=10731132; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., RA Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., RA Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Y16225; CAA76124.1; -. DR EMBL; AF043263; AAC38823.1; -. DR EMBL; AE003409; AAF44873.1; -. DR EMBL; AE003643; AAF53394.1; -. DR FLYBASE; FBgn0020258; ppk. DR INTERPRO; IPR001873; -. DR PFAM; PF00858; ASC; 1. KW Ionic channel. FT CONFLICT 603 603 K -> N (IN REF. 1). SQ SEQUENCE 606 AA; 69395 MW; 4FA457EA611F7C3B CRC64; MAEIREDEEE KKSGISILPG PELLALPGFD TRASIASAAL SDVPSDVIIK SRIRYGSPLS ACKGLLLEYA KSTTIHGIRY IFEVHRPIYE KLYWLFFTCI SVYFAVSLIW DTYLKWQESP VILGFDETLV PVHKIPFPTI TICPEIKMER NVFDYTNVSR QLWEEYKQNG NISDLDDEDL ARMAVAMHIC DSEVVQRFTP LLSQLNPPNV DVTQTLIDLS ISKNETGPFC KWNGRFYFCD KIFDFVATDE GICYQFNGLR PKDIYRDEKF ISYVDPDVVD FNKYFDVDLP PWNNITGNWS LDTGFVDQGQ NAYPQRTVFS SVKNGFFAFL QGLQHNFDYD CRSFKQGYKV FLNSPESVPL TTGNYILVPH GDEVLVSVLP AYVVSTDNLH EITPEKRQCL FDDERSLRFF RSYSQSNCQT ECLANYTVSK CGCAKFWMPK PLGTPVCGLK DINCYTSAQD ELYTLMQNQT MAKSIDESVD ITCNCMPACT SLEYNFEISR AKYDVAKTIR AFREEYEHTD AIGSRLSVYF KEHQFTAIKR TILFGVSTLI SNCGGICGLF MGISCLSFLE LIYFFCMRIC GSCRDRRKHK IQQQNSVDLP EEKSEN //