ID CSP2_STROR Reviewed; 41 AA. AC O33690; DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot. DT 01-JAN-1998, sequence version 1. DT 01-OCT-2014, entry version 46. DE RecName: Full=Competence-stimulating peptide; DE Short=CSP; DE Flags: Precursor; GN Name=comC; OS Streptococcus oralis. OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; OC Streptococcus. OX NCBI_TaxID=1303; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=DSM 20066; RX PubMed=9352904; RA Haevarstein L.S., Hakenbeck R., Gaustad P.; RT "Natural competence in the genus Streptococcus: evidence that RT streptococci can change pherotype by interspecies recombinational RT exchanges."; RL J. Bacteriol. 179:6589-6594(1997). CC -!- FUNCTION: Acts as a pheromone, induces cells to develop competence CC for genetic transformation. CC -!- SUBCELLULAR LOCATION: Secreted. CC -!- SIMILARITY: Belongs to the ComC family. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJ000874; CAA04364.1; -; Genomic_DNA. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. DR GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW. DR InterPro; IPR010133; Bacteriocin_signal_seq. DR InterPro; IPR004288; Competence_ComC. DR Pfam; PF03047; ComC; 1. DR TIGRFAMs; TIGR01847; bacteriocin_sig; 1. PE 3: Inferred from homology; KW Competence; Pheromone; Secreted. FT PROPEP 1 24 {ECO:0000255}. FT /FTId=PRO_0000005879. FT PEPTIDE 25 41 Competence-stimulating peptide. FT /FTId=PRO_0000005880. SQ SEQUENCE 41 AA; 4961 MW; B202A064BCD451AD CRC64; MKNTVKLEQF KEVTEAELQE IRGGDWRISE TIRNLIFPRR K //