ID O22906 PRELIMINARY; PRT; 230 AA. AC O22906; DT 01-JAN-1998 (TrEMBLrel. 05, Created) DT 01-JAN-1998 (TrEMBLrel. 05, Last sequence update) DT 01-JUN-2003 (TrEMBLrel. 24, Last annotation update) DE Putative peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) DE (Rotamase). GN AT2G47320. OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicots; rosids; OC eurosids II; Brassicales; Brassicaceae; Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=cv. Columbia; RX MEDLINE=20083487; PubMed=10617197; RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H., Moffat K.S., RA Cronin L.A., Shen M., VanAken S.E., Umayam L., Tallon L.J., Gill J.E., RA Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., RA Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., RA Salzberg S.L., Fraser C.M., Venter J.C.; RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis RT thaliana."; RL Nature 402:761-768(1999). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=cv. Columbia; RA Lin X.; RL Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: PPIASES ACCELERATE THE FOLDING OF PROTEINS (BY CC SIMILARITY). CC -!- CATALYTIC ACTIVITY: PEPTIDYLPROLINE (OMEGA=180) = PEPTIDYLPROLINE CC (OMEGA=0). CC -!- SIMILARITY: BELONGS TO THE CYCLOPHILIN-TYPE PPIASE FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC002337; AAB63832.1; -. DR PIR; G84913; G84913. DR HSSP; Q27450; 1C5F. DR GO; GO:0004600; F:cyclophilin; IEA. DR GO; GO:0042027; F:cyclophilin-type peptidy-prolyl cis-trans i...; IEA. DR GO; GO:0030051; F:FK506-sensitive peptidyl-prolyl cis-trans i...; IEA. DR GO; GO:0016853; F:isomerase activity; IEA. DR GO; GO:0006457; P:protein folding; IEA. DR InterPro; IPR002130; CSA_PPIase. DR Pfam; PF00160; pro_isomerase; 1. DR PRINTS; PR00153; CSAPPISMRASE. DR PROSITE; PS50072; CSA_PPIASE_2; 1. KW Isomerase; Rotamase. SQ SEQUENCE 230 AA; 26042 MW; 6198D43EE5B9552F CRC64; MAKIKPQALL QQSKKKKGPS RISITNIVIY TLAVLLLVFV LFSAYRRWTH RSEIPTHNGR SVLEDAAFPG MKNVDLPRFA TLDTGKGSVT IELFKDTAPN VVDQFMKFCQ DGYFKGFLFS RVVKHFVIQA GDSAEFDAVK DWALDRKNID TSLKHEEFMV GTPKAKNEQG GFEFFIVSAQ IKDLNEKLTV FGRVSKGQDV VQEIEEVETD DQYQPKSPIE IMSVTLLQDM //