ID O22508_SOLTU Unreviewed; 861 AA. AC O22508; DT 01-JAN-1998, integrated into UniProtKB/TrEMBL. DT 01-JAN-1998, sequence version 1. DT 18-MAY-2010, entry version 67. DE RecName: Full=Lipoxygenase; DE EC=1.13.11.12; GN Name=plox2; OS Solanum tuberosum (Potato). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; OC Solanum. OX NCBI_TaxID=4113; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Lehmi Russet; TISSUE=Tuber; RA Fidantsef A.L., Bostock R.M.; RT "Solanum tuberosum (Lehmi Russet) lipoxygenase (plox2) mRNA, complete RT cds."; RL Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Plant lipoxygenase may be involved in a number of CC diverse aspects of plant physiology including growth and CC development, pest resistance, and senescence or responses to CC wounding (By similarity). CC -!- CATALYTIC ACTIVITY: Linoleate + O(2) = (9Z,11E)-(13S)-13- CC hydroperoxyoctadeca-9,11-dienoate. CC -!- COFACTOR: Iron (By similarity). CC -!- PATHWAY: Lipid metabolism; oxylipin biosynthesis. CC -!- SIMILARITY: Belongs to the lipoxygenase family. CC -!- SIMILARITY: Contains 1 PLAT domain.. CC -!- SIMILARITY: Contains 1 lipoxygenase domain.. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF019614; AAB81595.1; -; mRNA. DR HSSP; P08170; 1FGT. DR SMR; O22508; 18-861. DR GO; GO:0005506; F:iron ion binding; IEA:InterPro. DR GO; GO:0016165; F:lipoxygenase activity; IEA:EC. DR GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW. DR GO; GO:0031408; P:oxylipin biosynthetic process; IEA:UniProtKB-KW. DR InterPro; IPR008976; Lipase_LipOase. DR InterPro; IPR000907; LipOase. DR InterPro; IPR013819; LipOase_C. DR InterPro; IPR020834; LipOase_CS. DR InterPro; IPR020833; LipOase_Fe_BS. DR InterPro; IPR001024; LipOase_LH2. DR InterPro; IPR001246; LipOase_pln. DR Gene3D; G3DSA:2.60.60.20; Lipase_LipOase; 1. DR PANTHER; PTHR11771; LipOase; 1. DR Pfam; PF00305; Lipoxygenase; 1. DR Pfam; PF01477; PLAT; 1. DR PRINTS; PR00087; LIPOXYGENASE. DR PRINTS; PR00468; PLTLPOXGNASE. DR SMART; SM00308; LH2; 1. DR SUPFAM; SSF49723; Lipase_LipOase; 1. DR SUPFAM; SSF48484; Lipoxygenase; 1. DR PROSITE; PS00711; LIPOXYGENASE_1; 1. DR PROSITE; PS00081; LIPOXYGENASE_2; 1. DR PROSITE; PS51393; LIPOXYGENASE_3; 1. DR PROSITE; PS50095; PLAT; 1. PE 2: Evidence at transcript level; KW Dioxygenase; Fatty acid biosynthesis; Iron; Lipid synthesis; KW Metal-binding; Oxidoreductase; Oxylipin biosynthesis. SQ SEQUENCE 861 AA; 97020 MW; 92C31F6EAF55FB58 CRC64; MIGQITSGLF GGHDDSKKVK GTVVMMNKNV LDFTDLASSL TGKIFDVLGQ KVSFQLISSV QGDPTNGLQG KHSNPAYLEN SLFTLTPLTA GSETAFGVTF DWNEEFGVPG AFIIKNMHIT EFFLKSLTLE DVPNHGKVHF VCNSWVYPSL NYKSDRIFFA NQPYLPSETP ELLRKYRENE LLTLRGDGTG KREAWDRIYD YDIYNDLGNP DQGKENVRTT LGGSAEYPYP RRGRTGRPPT RTDPKVKSRI PLILSLDIYV PRDERFGHLK MSDFLTYALK SIVQFILPEL HALFDGTPNE FDSFEDVLRL YEGGIKLPQG PLFKALTAAI PLEMIRELLR TDGEGILRFP TPLVIKDSKT AWRTDEEFAR EMLAGVNPII ISRLQEFPPK SKLDPEAYGN QNSTITAEHI EDKLDGLTVD EAMNNNKLFI LNHHDVIIPY LRRINTTITK TYASRTLLFL QDNGSLKPLA IELSLPHPDG DQFGVTSKVY TPTDQGVESS IWQLAKAYVA VNDTGVHQLI SHWLNTHAVI EPFVIATNRQ LSVLHPIHKL LYPHFRDTMN INASARQILV NAGGVLESTV FQSKFAMEMS AVVYKDWVFP DQALPADLVK RGVAVEDSSS PHGVRLLIED YPYAVDGLEI WSAIKSWVTD YCSFYYGSDE EILKDNELQA WWKELREVGH GDKKNEPWWP EMKTPQELID SCTTIIWIAS ALHAAVNFGQ YPYAGYLPNR PTVSRRFMPE PGTPEYEELK RNPDKAFLKT ITAQLQTLLG VSLVEILSRH TTDEIYLGQR ESPEWTKDKE PLAAFDRFGK KLTDIEKQII QRNGDNILTN RSGPVNAPYT LLFPTSEGGL TGKGIPNSVS I //