ID Z297_HUMAN STANDARD; PRT; 634 AA. AC O15209; Q8WV82; DT 28-FEB-2003 (Rel. 41, Created) DT 28-FEB-2003 (Rel. 41, Last sequence update) DT 15-SEP-2003 (Rel. 42, Last annotation update) DE Zinc finger protein 297 (BING1 protein). GN ZNF297 OR BING1. OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP SEQUENCE FROM N.A. RX MEDLINE=98213668; PubMed=9545376; RA Herberg J.A., Beck S., Trowsdale J.; RT "TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a RT dense cluster at the centromeric end of the MHC."; RL J. Mol. Biol. 277:839-857(1998). RN [2] RP SEQUENCE FROM N.A. RC TISSUE=Lymph; RX MEDLINE=22388257; PubMed=12477932; RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., RA Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., RA Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., RA Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., RA Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., RA Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., RA Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., RA Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., RA Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., RA Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., RA Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., RA Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., RA Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., RA Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., RA Butterfield Y.S.N., Krzywinski M.I., Skalska U., Smailus D.E., RA Schnerch A., Schein J.E., Jones S.J.M., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length RT human and mouse cDNA sequences."; RL Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002). CC -!- FUNCTION: MAY FUNCTION AS A TRANSCRIPTION FACTOR. CC -!- SUBCELLULAR LOCATION: Nuclear (Probable). CC -!- SIMILARITY: BELONGS TO THE KRUEPPEL FAMILY OF C2H2-TYPE ZINC- CC FINGER PROTEINS. CC -!- SIMILARITY: Contains 1 BTB/POZ domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Z97184; CAB09990.1; -. DR EMBL; Z97183; CAB09987.1; -. DR EMBL; BC018541; AAH18541.1; -. DR HSSP; Q05516; 1CS3. DR Genew; HGNC:13085; ZNF297. DR GO; GO:0005634; C:nucleus; TAS. DR GO; GO:0003677; F:DNA binding activity; TAS. DR InterPro; IPR000210; BTB_POZ. DR InterPro; IPR007087; Znf_C2H2. DR Pfam; PF00651; BTB; 1. DR Pfam; PF00096; zf-C2H2; 3. DR ProDom; PD000003; Znf_C2H2; 1. DR SMART; SM00225; BTB; 1. DR SMART; SM00355; ZnF_C2H2; 2. DR PROSITE; PS50097; BTB; 1. DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1. DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2. KW Transcription regulation; DNA-binding; Zinc-finger; Metal-binding; KW Nuclear protein; Repeat. FT DOMAIN 57 121 BTB. FT ZN_FING 486 507 C2H2-TYPE (ATYPICAL). FT ZN_FING 513 535 C2H2-TYPE. FT ZN_FING 541 562 C2H2-TYPE. FT CONFLICT 310 310 T -> A (IN REF. 2). SQ SEQUENCE 634 AA; 65602 MW; 9CC1867213D6DEF7 CRC64; MEPSPLSPSG AALPLPLSLA PPPLPLPAAA VVHVSFPEVT SALLESLNQQ RLQGQLCDVS IRVQGREFRA HRAVLAASSP YFHDQVLLKG MTSISLPSVM DPGAFETVLA SAYTGRLSMA AADIVNFLTV GSVLQMWHIV DKCTELLREG RASATTTITT AAATSVTVPG AGVPSGSGGT VAPATMGSAR SHASSRASEN QSPSSSNYFS PRESTDFSSS SQEAFAASAV GSGERRGGGP VFPAPVVGSG GATSGKLLLE ADELCDDGGD GRGAVVPGAG LRRPTYTPPS IMPQKHWVYV KRGGNCPAPT PLVPQDPDLE EEEEEEDLVL TCEDDEDEEL GGSSRVPVGG GPEATLSISD VRTLSEPPDK GEEQVNFCES SNDFGPYEGG GPVAGLDDSG GPTPSSYAPS HPPRPLLPLD MQGNQILVFP SSSSSSSSQA PGQPPGNQAE HGAVTVGGTS VGSLGVPGSV GGVPGGTGSG DGNKIFLCHC GKAFSHKSMR DRHVNMHLNL RPFDCPVCNK KFKMKHHLTE HMKTHTGLKP YECGVCAKKF MWRDSFMRHR GHCERRHRLG GVGAVPGPGT PTGPSLPSKR ESPGVGGGSG DEASAATPPS SRRVWSPPRV HKVEMGFGGG GGAN //