ID NPF2_HUMAN STANDARD; PRT; 113 AA. AC O15130; DT 30-MAY-2000 (Rel. 39, Created) DT 30-MAY-2000 (Rel. 39, Last sequence update) DT 30-MAY-2000 (Rel. 39, Last annotation update) DE FMRFAMIDE-RELATED PEPTIDES PRECURSOR [CONTAINS: NEUROPEPTIDE DE SF (NPSF); NEUROPEPTIDE AF (NPAF)]. OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. RN [1] RP SEQUENCE FROM N.A. RC TISSUE=TESTIS; RX MEDLINE; 97367936. RA Perry S.J., Yi-Kung Huang E., Cronk D., Bagust J., Sharma R., RA Walker R.J., Wilson S., Burke J.F.; RT "A human gene encoding morphine modulating peptides related to NPFF RT and FMRFamide."; RL FEBS Lett. 409:426-430(1997). CC -!- FUNCTION: MORPHINE MODULATING PEPTIDES. CC -!- SIMILARITY: BELONGS TO THE FARP (FMRFAMIDE RELATED PEPTIDE) CC FAMILY. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF005271; AAB64288.1; -. KW Neuropeptide; Amidation; Cleavage on pair of basic residues; Signal. FT SIGNAL 1 20 POTENTIAL. FT PROPEP 21 65 FT PEPTIDE 66 76 NEUROPEPTIDE SF. FT PROPEP 79 92 FT PEPTIDE 93 110 NEUROPEPTIDE AF. FT MOD_RES 76 76 AMIDATION (G-77 PROVIDE AMIDE GROUP). FT MOD_RES 110 110 AMIDATION (G-111 PROVIDE AMIDE GROUP). SQ SEQUENCE 113 AA; 12440 MW; 1E9D4ED2A69238E3 CRC64; MDSRQAAALL VLLLLIDGGC AEGPGGQQED QLSAEEDSEP LPPQDAQTSG SLLHYLLQAM ERPGRSQAFL FQPQRFGRNT QGSWRNEWLS PRAGEGLNSQ FWSLAAPQRF GKK //