ID O14965 PRELIMINARY; PRT; 402 AA. AC O14965; DT 01-JAN-1998 (TrEMBLrel. 05, Created) DT 01-JAN-1998 (TrEMBLrel. 05, Last sequence update) DT 01-MAR-2001 (TrEMBLrel. 16, Last annotation update) DE AURORA/IPL1-RELATED KINASE. OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP SEQUENCE FROM N.A. RC TISSUE=BLOOD; RX MEDLINE=97298083; PubMed=9153231; RA Kimura M., Kotani S., Hattori T., Sumi N., Yoshioka T., Todokoro K., RA Okano Y.; RT "Cell cycle-dependent expression and spindle pole localization of a RT novel human protein kinase, Aik, related to Aurora of Drosophila and RT yeast Ipl1."; RL J. Biol. Chem. 272:13766-13771(1997). CC -!- SIMILARITY: TO THE SER/THR FAMILY OF PROTEIN KINASES. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; D84212; BAA23592.1; -. DR InterPro; IPR000719; -. DR InterPro; IPR002290; -. DR Pfam; PF00069; pkinase; 1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. DR SMART; SM00220; S_TKc; 1. KW ATP-binding; Serine/threonine-protein kinase; Transferase. SQ SEQUENCE 402 AA; 45934 MW; B20F528131F1D59F CRC64; MDRSKENCIS GPVKATAPVG GPKRVLVTQQ FPCQNPLPVN SGQAQRVLCP SNSSQRVPLQ AQKLVSSHKP VQNQKQKQLQ ATSVPHPVSR PLNNTQKSKQ PLPSHLKIIL RRNWHQNRKM KNQKEAVALE DFEIGRPLGK GKFGNVYLAR EKQSKFILAL KVLFKAQLEK AGVEHQLRRE VEIQSHLRHP NILRLYGYFH DATRVYLILE YAPLGTVYRE LQKLSKFDEQ RTANLYNRIA NALSYCHSKR VIHRDIKPEN LLLGSAGELK IADFGWSVHA PSSRRTTLCG TLDYLPPEMI EGRMHDEKVD LWSLGVLCYE FLVGKPPFEA NTYQETYKRI SRVEFTFPDF VTEGARDLIS RLLKHNPSQR PMLREVLEHP WITANSSKPS NCQNKESASK QS //