ID TYBY_HUMAN STANDARD; PRT; 43 AA. AC O14604; DT 15-JUL-1999 (Rel. 38, Created) DT 15-JUL-1999 (Rel. 38, Last sequence update) DT 15-JUL-1999 (Rel. 38, Last annotation update) DE THYMOSIN BETA-4, Y-CHROMOSOMAL. GN TMSB4Y OR TB4Y. OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia; OC Eutheria; Primates; Catarrhini; Hominidae; Homo. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 98022381. RA LAHN B.T., PAGE D.C.; RT "Functional coherence of the human Y chromosome."; RL Science 278:675-680(1997). CC -!- FUNCTION: EXACT PHYSIOLOGICAL ROLE IS NOT YET KNOWN. THYMIC CC HORMONE THAT INDUCES TERMINAL DEOXYNUCLEOTIDYLTRANSFERASE. CAN CC BIND TO ACTIN MONOMERS AND THUS TO INHIBIT ACTIN POLYMERIZATION CC (BY SIMILARITY). CC -!- SUBCELLULAR LOCATION: CYTOPLASMIC (BY SIMILARITY). CC -!- TISSUE SPECIFICITY: UBIQUITOUS. CC -!- SIMILARITY: BELONGS TO THE THYMOSIN BETA FAMILY. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF000989; AAC51836.1; -. DR MIM; 400017; -. DR PFAM; PF01290; Thymosin; 1. DR PROSITE; PS00500; THYMOSIN_B4; 1. KW T-cell differentiation; Immunopotentiation; Acetylation; Thymus; KW Actin-binding. FT INIT_MET 0 0 BY SIMILARITY. FT MOD_RES 1 1 ACETYLATION (BY SIMILARITY). SQ SEQUENCE 43 AA; 4881 MW; FEF07C63 CRC32; SDKPGMAEIE KFDKSKLKKT ETQEKNPLSS KETIEQERQA GES //