ID MEI4_SCHPO STANDARD; PRT; 517 AA. AC O13606; DT 01-OCT-2000 (Rel. 40, Created) DT 01-OCT-2000 (Rel. 40, Last sequence update) DT 01-OCT-2000 (Rel. 40, Last annotation update) DE MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR MEI4. GN MEI4 OR PI013. OS Schizosaccharomyces pombe (Fission yeast). OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; OC Schizosaccharomyces. OX NCBI_TaxID=4896; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=972; RX MEDLINE=98187633; PubMed=9528784; RA Horie S., Watanabe Y., Tanaka K., Nishiwaki S., Fujioka H., Abe H., RA Yamamoto M., Shimoda C.; RT "The Schizosaccharomyces pombe mei4+ gene encodes a meiosis-specific RT transcription factor containing a forkhead DNA-binding domain."; RL Mol. Cell. Biol. 18:2118-2129(1998). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=972; RA Machida M., Yamazaki S., Kunihiro S., Tanaka T., Kushida N., Jinno K., RA Haikawa Y., Yamazaki J., Yamamoto S., Sekine M., Oguchi A., Nagai Y., RA Sakai M., Aoki K., Ogura K., Kudoh Y., Kikuchi H., Zhang M.Q., RA Yanagida M.; RT "A 38 kb segment containing the cdc2 gene from the left arm of fission RT yeast chromosome II: sequence analysis and characterization of the RT genomic DNA and cDNAs encoded on the segment."; RL Yeast 16:71-80(2000). CC -!- FUNCTION: FUNCTIONS AS A MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR. CC BINDS TO THE 5'-GTAAAYA-3' CONSENSUS SEQUENCE OF THE PROMOTER OF CC THE SPO6 GENE. CC -!- SIMILARITY: CONTAINS 1 FORK-HEAD DOMAIN. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB012695; BAA25402.1; -. DR EMBL; AB004534; BAA21390.1; -. DR HSSP; Q63245; 2HFH. DR InterPro; IPR001766; Fork_head. DR Pfam; PF00250; Fork_head; 1. DR PRINTS; PR00053; FORKHEAD. DR SMART; SM00339; FH; 1. DR PROSITE; PS00657; FORK_HEAD_1; FALSE_NEG. DR PROSITE; PS00658; FORK_HEAD_2; 1. DR PROSITE; PS50039; FORK_HEAD_3; 1. KW Transcription regulation; DNA-binding; Nuclear protein; Activator; KW Meiosis. FT DNA_BIND 81 172 FORK-HEAD. SQ SEQUENCE 517 AA; 57684 MW; 05D912F04525C759 CRC64; MVENQGNVEA HGKPKKVILS LSLKESSKIN DSQNVSNVSS KEKCETEALL REENKENLSS DSIRQMIFGD EMAGFVDTGE KPPCSYATLI GLAILQSHNK QLTLSGIYTW IRNTFRYYLN HDGGWQNSIR HNLSLNKAFI KVEKPKGKTL KGHYWTIDPD HMQNFVSVRL HRSHSTDSNS KKRPSSKCHE IKPLTTREIP LARKRSRLNS FNSSTSTSGS SSNVAAEVSN DASQPSNQDS SLNSNIVKPP LPPSNVQSNS SSSENVPKPN AETQEDLPTI DAHESSLYEN VNDSRLYEVP ACRNMALNTG YSDADPGYLR TSFRSNSHNS LPYSANEEED VLQADFLVSQ QSSMVSSYVS SRDPHSMPYY RREPIPLRPS SRFYEYTRPT YGRTDTSCSA PGAFCSTQIN SPSSYINYSK CAPSSPTLSL QKHREHVKSL LYVPDLTPSF DGSDPWNPSS QLLSEPLFDQ HSFQSSLDDL MSVTCFRDSP ELNHESSGYS SAPLMPSNRA FINDFSL //