ID DAD1_CHICK STANDARD; PRT; 123 AA. AC O13113; DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot. DT 01-JUL-1997, sequence version 1. DT 07-FEB-2006, entry version 28. DE Defender against cell death 1 (DAD-1). GN Name=DAD1; OS Gallus gallus (Chicken). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Archosauria; Aves; Neognathae; Galliformes; Phasianidae; Phasianinae; OC Gallus. OX NCBI_TaxID=9031; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RX MEDLINE=97419167; PubMed=9271627; DOI=10.1007/s002510050291; RA Wang K., Gan L., Kuo C.L., Hood L.; RT "A highly conserved apoptotic suppressor gene is located near the RT chicken T-cell receptor alpha chain constant region."; RL Immunogenetics 46:376-382(1997). CC -!- FUNCTION: Loss of the DAD1 protein triggers apoptosis (By CC similarity). CC -!- SUBCELLULAR LOCATION: Membrane; multi-pass membrane protein CC (Potential). CC -!- SIMILARITY: Belongs to the DAD/OST2 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U83627; AAC60276.1; -; mRNA. DR Ensembl; ENSGALG00000000196; Gallus gallus. DR InterPro; IPR003038; DAD. DR PANTHER; PTHR10705; DAD; 1. DR Pfam; PF02109; DAD; 1. KW Apoptosis; Membrane; Transmembrane. FT CHAIN 1 123 Defender against cell death 1. FT /FTId=PRO_0000124015. FT TRANSMEM 41 61 Potential. FT TRANSMEM 63 83 Potential. SQ SEQUENCE 123 AA; 12926 MW; D468651E6A5D01C5 CRC64; MSGTAGSGVG AAGSVGSVVR RFLAEYGSGT SSRLKVLDAY LLYVMLTGAL QFGYCLGVGT FPFNSFLSGF ISAVGSFILG VCLRIQINPQ NKGEFQGISP ERAFADFLFA NTILHLVVIN FVG //