ID O11883_HBV Unreviewed; 154 AA. AC O11883; DT 01-JUL-1997, integrated into UniProtKB/TrEMBL. DT 01-JUL-1997, sequence version 1. DT 11-DEC-2013, entry version 51. DE SubName: Full=X peptide; DE SubName: Full=X protein; DE SubName: Full=X-protein; GN Name=X; OS Hepatitis B virus (HBV). OC Viruses; Retro-transcribing viruses; Hepadnaviridae; OC Orthohepadnavirus. OX NCBI_TaxID=10407; OH NCBI_TaxID=9606; Homo sapiens (Human). OH NCBI_TaxID=9598; Pan troglodytes (Chimpanzee). RN [1] RP NUCLEOTIDE SEQUENCE. RA Rao B.S., Casey J.L., Rinaudo J.S., Korba B.E.; RT "Complete nucleotide sequence of a molecular clone of hepatitis B RT virus from the 2.2.15 cell line."; RL Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Toshima 1; RX PubMed=17191017; DOI=10.1159/000098241; RA Michitaka K., Horiike N., Duong T.N., Yagura M., Harada H., RA Shibayama T., Inui A., Fujisawa T., Matsuura K., Hiasa Y., Onji M.; RT "Heterogeneity of hepatitis B virus genotype D in Japan."; RL Intervirology 50:150-155(2007). RN [3] RP NUCLEOTIDE SEQUENCE. RC STRAIN=P11, P16, P17, P19, P24, and P29; RG The Broad Institute Genome Sequencing Platform; RG The Broad Institute Genome Sequencing Center for Infectious Disease; RA Wortman J.R., Grad Y.J., Hanage W.P., Godfrey P., Cerqueira G.C., RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B., RA Mariani-Kurkdjian P., Gouali M., Bingen E., Lipsitch M., Waldor M.K., RA Weill F.X., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., RA Chapman S.B., Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., RA Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A., RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., RA Shea T., Sisk P., Sykes S., Nusbaum C., Birren B.; RT "The Genome Sequence of Escherichia coli Ec11-4986."; RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Host cytoplasm. Host nucleus. Host CC mitochondrion (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U95551; AAB59970.1; -; Genomic_DNA. DR EMBL; JX898686; AGA16743.1; -; Genomic_DNA. DR EMBL; JX898689; AGA16764.1; -; Genomic_DNA. DR EMBL; JX898690; AGA16771.1; -; Genomic_DNA. DR EMBL; JX898691; AGA16778.1; -; Genomic_DNA. DR EMBL; JX898692; AGA16785.1; -; Genomic_DNA. DR EMBL; JX898694; AGA16799.1; -; Genomic_DNA. DR EMBL; AB210819; BAE93198.1; -; Genomic_DNA. DR GO; GO:0033650; C:host cell mitochondrion; IEA:UniProtKB-KW. DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-KW. DR GO; GO:0039652; P:activation by virus of host NF-kappaB transcription factor activity; IEA:UniProtKB-KW. DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. DR GO; GO:0039592; P:suppression by virus of G2/M transition of host mitotic cell cycle; IEA:UniProtKB-KW. DR GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. DR GO; GO:0019079; P:viral genome replication; IEA:InterPro. DR InterPro; IPR000236; Transactivation_prot_X. DR Pfam; PF00739; X; 1. PE 3: Inferred from homology; KW Activation of host NF-kappa-B by virus; Activator; Apoptosis; KW Host cytoplasm; Host G2/M cell cycle arrest by virus; KW Host mitochondrion; Host nucleus; Host-virus interaction; KW Modulation of host cell cycle by virus; Transcription; KW Transcription regulation. SQ SEQUENCE 154 AA; 16611 MW; 895800BDF24CEA17 CRC64; MAARLCCQLD PARDVLCLRP VGAESCGRPF SGSLGTLSSP SPSAVPTDHG AHLSLRGLPV CAFSSAGPCA LRFTSARRME TTVNAHRMLP KVLHKRTLGL SAMSTTDLEA YFKDCLFKDW EELGEEIRLK VFVLGGCRHK LVCAPAPCNF FTSA //