ID GAT2_MOUSE STANDARD; PRT; 480 AA. AC O09100; DT 01-NOV-1997 (REL. 35, CREATED) DT 01-NOV-1997 (REL. 35, LAST SEQUENCE UPDATE) DT 01-NOV-1997 (REL. 35, LAST ANNOTATION UPDATE) DE ENDOTHELIAL TRANSCRIPTION FACTOR GATA-2. GN GATA2. OS MUS MUSCULUS (MOUSE). OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA; OC EUTHERIA; RODENTIA. RN [1] RP SEQUENCE FROM N.A. RC TISSUE=LIVER; RA SUWABE N., MINEGISHI N., YAMAMOTO M.; RL SUBMITTED (DEC-1996) TO EMBL/GENBANK/DDBJ DATA BANKS. CC -!- FUNCTION: TRANSCRIPTIONAL ACTIVATOR WHICH REGULATES ENDOTHELIN-1 CC GENE EXPRESSION IN ENDOTHELIAL CELLS. BINDS TO THE CONSENSUS CC SEQUENCE 5'-AGATAG-3'. CC -!- SUBCELLULAR LOCATION: NUCLEAR. CC -!- SIMILARITY: TO OTHER GATA-TYPE TRANSCRIPTION FACTORS. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB000096; G1754586; -. DR MGD; MGI:95662; GATA2. DR PROSITE; PS00344; GATA_ZN_FINGER; 2. KW TRANSCRIPTION REGULATION; ACTIVATOR; DNA-BINDING; ZINC-FINGER; KW NUCLEAR PROTEIN. FT ZN_FING 295 319 GATA-TYPE. FT ZN_FING 349 373 GATA-TYPE. SQ SEQUENCE 480 AA; 50450 MW; 600E7988 CRC32; MEVAPEQPRW MAHPAVLNAQ HPDSHHPGLA HNYMEPAQLL PPDEVDVFFN HLDSQGNPYY ANPAHARARV SYSPAHARLT GGQMCRPHLL HSPGLPWLDG GKAALSAAAA HHHSPWTVSP FSKTPLHPSA AGAPGGPLSV YPGSAGGSGG GSGSSVASLT PTAAHSGSHL FGFPPTPPKE VSPDPSTTGA ASPASSSAGG SVARGEDKDG VKYQVSLSES MKMEGGSPLR PGLATMGTQP ATHHPIPTYP SYVPAAAHDY GSSLFHPGGF LGGPASSFTP KQRSKARSCS EGRECVNCGA TATPLWRRDG TGHYLCNACG LYHKMNGQNR PLIKPKRRLS AARRAGTCCA NCQTTTTTLW RRNANGDPVC NACGLYYKLH NVNRPLTMKK EGIQTRNRKM SSKSKKSKKG AECFEELSKC MQEKSPPFSA AALAGHMAPV GHLPPLSHSG HILPTPTPIH PSSSLSFGHP HPSSMVTAMG //