ID O08721 PRELIMINARY; PRT; 898 AA. AC O08721; DT 01-JUL-1997 (TrEMBLrel. 04, Created) DT 01-JUL-1997 (TrEMBLrel. 04, Last sequence update) DT 01-JUN-2003 (TrEMBLrel. 24, Last annotation update) DE Transmembrane receptor UNC5H1. OS Rattus norvegicus (Rat). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Rattus. OX NCBI_TaxID=10116; RN [1] RP SEQUENCE FROM N.A. RC TISSUE=Brain, and Ventral spinal cord; RX MEDLINE=97271897; PubMed=9126742; RA Leonardo E.D., Hinck L., Masu M., Keino-Masu K., Ackerman S.L., RA Tessier-Lavigne M.; RT "Vertebrate homologues of C. elegans UNC-5 are candidate netrin RT receptors."; RL Nature 386:833-838(1997). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U87305; AAB57678.1; -. DR GO; GO:0004872; F:receptor activity; IEA. DR GO; GO:0007165; P:signal transduction; IEA. DR InterPro; IPR000488; Death. DR InterPro; IPR003599; Ig. DR InterPro; IPR007110; Ig-like. DR InterPro; IPR000884; TSP1. DR InterPro; IPR008085; TSP_1. DR InterPro; IPR000906; ZU5. DR Pfam; PF00531; death; 1. DR Pfam; PF00047; ig; 1. DR Pfam; PF00090; tsp_1; 2. DR Pfam; PF00791; ZU5; 1. DR PRINTS; PR01705; TSP1REPEAT. DR SMART; SM00005; DEATH; 1. DR SMART; SM00409; IG; 1. DR SMART; SM00209; TSP1; 2. DR SMART; SM00218; ZU5; 1. DR PROSITE; PS50092; TSP1; 2. KW Receptor. SQ SEQUENCE 898 AA; 98840 MW; 7A3CBCB9E7ACA135 CRC64; MAVRPGLWPV LLGIVLAAWL RGSGAQQSAT VANPVPGANP DLLPHFLVEP EDVYIVKNKP VLLVCKAVPA TQIFFKCNGE WVRQVDHVIE RSTDSSSGLP TMEVRINVSR QQVEKVFGLE EYWCQCVAWS SSGTTKSQKA YIRIAYLRKN FEQEPLAKEV SLEQGIVLPC RPPEGIPPAE VEWLRNEDLV DPSLDPNVYI TREHSLVVRQ ARLADTANYT CVAKNIVARR RSTSAAVIVY VNGGWSTWTE WSVCSASCGR GWQKRSRSCT NPAPLNGGAF CEGQNVQKTA CATLCPVDGS WSSWSKWSAC GLDCTHWRSR ECSDPAPRNG GEECRGADLD TRNCTSDLCL HTASCPEDVA LYIGLVAVAV CLFLLLLALG LIYCRKKEGL DSDVADSSIL TSGFQPVSIK PSKADNPHLL TIQPDLSTTT TTYQGSLCSR QDGPSPKFQL SNGHLLSPLG SGRHTLHHSS PTSEAEDFVS RLSTQNYFRS LPRGTSNMAY GTFNFLGGRL MIPNTGISLL IPPDAIPRGK IYEIYLTLHK PEDVRLPLAG CQTLLSPVVS CGPPGVLLTR PVILAMDHCG EPSPDSWSLR LKKQSCEGSW EDVLHLGEES PSHLYYCQLE AGACYVFTEQ LGRFALVGEA LSVAATKRLR LLLFAPVACT SLEYNIRVYC LHDTHDALKE VVQLEKQLGG QLIQEPRVLH FKDSYHNLRL SIHDVPSSLW KSKLLVSYQE IPFYHIWNGT QQYLHCTFTL ERINASTSDL ACKVWVWQVE GDGQSFNINF NITKDTRFAE LLALESEGGV PALVGPSAFK IPFLIRQKII ASLDPPCSRG ADWRTLAQKL HLDSHLSFFA SKPSPTAMIL NLWEARHFPN GNLGQLAAAV AGLGQPDAGL FTVSEAEC //