ID O02271_CAEEL Unreviewed; 370 AA. AC O02271; DT 01-JUL-1997, integrated into UniProtKB/TrEMBL. DT 01-JUL-1997, sequence version 1. DT 02-OCT-2024, entry version 148. DE SubName: Full=Nematode cuticle collagen N-terminal domain-containing protein {ECO:0000313|EMBL:CAB05733.1}; GN Name=col-64 {ECO:0000313|EMBL:CAB05733.1, GN ECO:0000313|WormBase:F52F12.2}; GN ORFNames=CELE_F52F12.2 {ECO:0000313|EMBL:CAB05733.1}, F52F12.2 GN {ECO:0000313|WormBase:F52F12.2}; OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; OC Caenorhabditis. OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAB05733.1, ECO:0000313|Proteomes:UP000001940}; RN [1] {ECO:0000313|EMBL:CAB05733.1, ECO:0000313|Proteomes:UP000001940} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAB05733.1, RC ECO:0000313|Proteomes:UP000001940}; RX PubMed=9851916; DOI=10.1126/science.282.5396.2012; RG The C. elegans sequencing consortium; RA Sulson J.E., Waterston R.; RT "Genome sequence of the nematode C. elegans: a platform for investigating RT biology."; RL Science 282:2012-2018(1998). CC -!- SUBUNIT: Collagen polypeptide chains are complexed within the cuticle CC by disulfide bonds and other types of covalent cross-links. CC {ECO:0000256|ARBA:ARBA00011518}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BX284601; CAB05733.1; -; Genomic_DNA. DR PIR; T22510; T22510. DR RefSeq; NP_492619.1; NM_060218.1. DR AlphaFoldDB; O02271; -. DR SMR; O02271; -. DR STRING; 6239.F52F12.2.1; -. DR PaxDb; 6239-F52F12.2; -. DR EnsemblMetazoa; F52F12.2.1; F52F12.2.1; WBGene00000640. DR GeneID; 186127; -. DR KEGG; cel:CELE_F52F12.2; -. DR UCSC; F52F12.2; c. elegans. DR AGR; WB:WBGene00000640; -. DR CTD; 186127; -. DR WormBase; F52F12.2; CE10842; WBGene00000640; col-64. DR eggNOG; KOG3544; Eukaryota. DR HOGENOM; CLU_001074_4_3_1; -. DR InParanoid; O02271; -. DR OMA; CDCDTGP; -. DR OrthoDB; 5648809at2759; -. DR Proteomes; UP000001940; Chromosome I. DR Bgee; WBGene00000640; Expressed in adult organism and 2 other cell types or tissues. DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW. DR GO; GO:0042302; F:structural constituent of cuticle; IEA:InterPro. DR InterPro; IPR002486; Col_cuticle_N. DR InterPro; IPR008160; Collagen. DR InterPro; IPR050632; Nematode_Cuticular_Collagen. DR PANTHER; PTHR24637:SF324; COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN; 1. DR PANTHER; PTHR24637; COLLAGEN; 1. DR Pfam; PF01484; Col_cuticle_N; 1. DR Pfam; PF01391; Collagen; 1. DR SMART; SM01088; Col_cuticle_N; 1. PE 4: Predicted; KW Collagen {ECO:0000313|EMBL:CAB05733.1}; KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000001940}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 6..31 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 2..58 FT /note="Nematode cuticle collagen N-terminal" FT /evidence="ECO:0000259|SMART:SM01088" FT REGION 88..122 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 134..370 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 273..326 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 337..362 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 370 AA; 37448 MW; E7B5543C404A04F1 CRC64; MGYGTNVASG VTVICAAFLI PMLTCTISLF YEVAQMHMSA MDGMDEFKLY ANGAWEDMLP ATRLPREASP TPDSNKDPCD CDTGPAINCP VGPHGPRGRP GRKGADGPHG GQGRKGPDGM DVFKEMIGPV ECIPCVAGEP GPPGENGSVG EKGEDGQPGS PGKPGEDGES GTDGEPGFIG FPGFPGAPGE NGEQGNNATR GVGIPGPAGP PGPPGEVGMP GVTGETGEDG HDGPEGPEGP AGNIGDIAEE GPDGIPGEQG VPGFDSGYCP CPRRSSSRVS PSGGSSPISD TFIASPTLLP PSTTLSSTPP TISPSAPTLL PTRSPKSREE TPTRREEQQV PPNPSSSEVP ETGDSANSQN FGGYLALKRL //