ID O01965_CAEEL Unreviewed; 494 AA. AC O01965; DT 01-JUL-1997, integrated into UniProtKB/TrEMBL. DT 01-DEC-2001, sequence version 3. DT 08-JUN-2016, entry version 111. DE SubName: Full=ARI (Ubiquitin ligase Ariadne) homolog {ECO:0000313|EMBL:CCD61206.1}; GN Name=ari-1 {ECO:0000313|EMBL:CCD61206.1, GN ECO:0000313|WormBase:C27A12.8}; GN ORFNames=C27A12.8 {ECO:0000313|WormBase:C27A12.8}, CELE_C27A12.8 GN {ECO:0000313|EMBL:CCD61206.1}; OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD61206.1, ECO:0000313|Proteomes:UP000001940}; RN [1] {ECO:0000313|EMBL:CCD61206.1, ECO:0000313|Proteomes:UP000001940} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD61206.1, RC ECO:0000313|Proteomes:UP000001940}; RX PubMed=9851916; DOI=10.1126/science.282.5396.2012; RG Caenorhabditis elegans Sequencing Consortium; RA Sulson J.E., Waterston R.; RT "Genome sequence of the nematode C. elegans: a platform for RT investigating biology."; RL Science 282:2012-2018(1998). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BX284601; CCD61206.1; -; Genomic_DNA. DR PIR; H87793; H87793. DR RefSeq; NP_491749.2; NM_059348.5. DR UniGene; Cel.7447; -. DR ProteinModelPortal; O01965; -. DR SMR; O01965; 51-490. DR IntAct; O01965; 1. DR STRING; 6239.C27A12.8.2; -. DR EPD; O01965; -. DR PaxDb; O01965; -. DR EnsemblMetazoa; C27A12.8.1; C27A12.8.1; WBGene00016158. DR EnsemblMetazoa; C27A12.8.2; C27A12.8.2; WBGene00016158. DR GeneID; 172284; -. DR KEGG; cel:CELE_C27A12.8; -. DR UCSC; C27A12.8.1; c. elegans. DR CTD; 32796; -. DR WormBase; C27A12.8; CE29680; WBGene00016158; ari-1. DR eggNOG; KOG1815; Eukaryota. DR eggNOG; ENOG410XP9Y; LUCA. DR GeneTree; ENSGT00840000129790; -. DR HOGENOM; HOG000216612; -. DR InParanoid; O01965; -. DR KO; K11968; -. DR OMA; TLARYLH; -. DR PhylomeDB; O01965; -. DR Reactome; R-CEL-1169408; ISG15 antiviral mechanism. DR Proteomes; UP000001940; Chromosome I. DR GO; GO:0005737; C:cytoplasm; IDA:WormBase. DR GO; GO:0005634; C:nucleus; IDA:WormBase. DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro. DR InterPro; IPR031127; E3_UB_ligase_RBR. DR InterPro; IPR002867; IBR_dom. DR PANTHER; PTHR11685; PTHR11685; 1. DR Pfam; PF01485; IBR; 2. DR SMART; SM00647; IBR; 2. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000001940}; KW Ligase {ECO:0000313|EMBL:CCD61206.1}; KW Metal-binding {ECO:0000256|SAAS:SAAS00468077}; KW Proteomics identification {ECO:0000213|EPD:O01965, KW ECO:0000213|PeptideAtlas:O01965}; KW Reference proteome {ECO:0000313|Proteomes:UP000001940}; KW Zinc {ECO:0000256|SAAS:SAAS00468092}; KW Zinc-finger {ECO:0000256|SAAS:SAAS00468068}. FT DOMAIN 194 255 IBR-type. {ECO:0000259|SMART:SM00647}. FT DOMAIN 263 327 IBR-type. {ECO:0000259|SMART:SM00647}. SQ SEQUENCE 494 AA; 57251 MW; 25BF128B84F805E3 CRC64; MSSDDEINMD DSDSSQGEID DGCMSDDDGI VLESREQNSS DYKDNGEPDN EVLNHDSLEA EMKKTITDVQ AVLQVKTGVC RILLHKYKWN KESLLERFYE HPDTTTFLID AHVIPRRQER LPAGDAECDI CCSLGELSGL SCNHRACTQC WKAYLTNKIA NNAQSEIECM APNCKLLIED EKVMFYITDP TVIATYRKLI VASYVETNRL LKWCPGIDCG KAVRVSHWEP RLVVCSCGSR FCFSCGHDWH EPVNCRLLKL WLKKCNDDSE TSNWINANTK ECPKCMITIE KDGGCNHMTC KNTACRFEFC WMCLGPWEPH GSSWYSCNRF DDSAAKNARD AQEVSRANLQ RYLFYYNRYM GHQQSLRLEG KLYATVKSKM EQMQTLSMSW IEVQFLRKAV DVLSECRRTL MFTYAFAFYL KRDNNAIIFE SNQKDLEMET EQLSGFLERD LDNENLVTLK QKVQDKYRYV EHRRKVLLDH CSEGADQELW VFNE //