ID N9U355_9GAMM Unreviewed; 808 AA. AC N9U355; DT 26-JUN-2013, integrated into UniProtKB/TrEMBL. DT 26-JUN-2013, sequence version 1. DT 13-NOV-2013, entry version 5. DE SubName: Full=Bifunctional aspartate kinase II/homoserine dehydrogenase II; DE EC=1.1.1.3; GN Name=metL; ORFNames=G114_06497; OS Aeromonas diversa 2478-85. OC Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales; OC Aeromonadaceae; Aeromonas. OX NCBI_TaxID=1268237; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=2478-85; RA Farfan M., Spataro N., Sanglas A., Albarral V., Loren J.G., Bosch E., RA Fuste M.C.; RT "Draft Genome Sequence of the Aeromonas diversa Type Strain."; RL Genome Announc. 1:E00330-13(2013). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; APVG01000012; ENY72725.1; -; Genomic_DNA. DR EnsemblBacteria; ENY72725; ENY72725; G114_06497. DR GO; GO:0004072; F:aspartate kinase activity; IEA:InterPro. DR GO; GO:0004412; F:homoserine dehydrogenase activity; IEA:UniProtKB-EC. DR GO; GO:0050661; F:NADP binding; IEA:InterPro. DR GO; GO:0009067; P:aspartate family amino acid biosynthetic process; IEA:InterPro. DR Gene3D; 3.40.1160.10; -; 2. DR Gene3D; 3.40.50.720; -; 1. DR InterPro; IPR001048; Asp/Glu/Uridylate_kinase. DR InterPro; IPR005106; Asp/hSer_DH_NAD-bd. DR InterPro; IPR001341; Asp_kinase_dom. DR InterPro; IPR018042; Aspartate_kinase_CS. DR InterPro; IPR011147; Bifunc_aspartokin/hSer_DH. DR InterPro; IPR001342; HDH_cat. DR InterPro; IPR019811; HDH_CS. DR InterPro; IPR016040; NAD(P)-bd_dom. DR Pfam; PF00696; AA_kinase; 1. DR Pfam; PF00742; Homoserine_dh; 1. DR Pfam; PF03447; NAD_binding_3; 1. DR PIRSF; PIRSF000727; ThrA; 1. DR SUPFAM; SSF53633; SSF53633; 1. DR TIGRFAMs; TIGR00657; asp_kinases; 1. DR PROSITE; PS00324; ASPARTOKINASE; 1. DR PROSITE; PS01042; HOMOSER_DHGENASE; 1. PE 4: Predicted; KW Kinase; Oxidoreductase; Transferase. SQ SEQUENCE 808 AA; 89239 MW; EDA418A3F2545555 CRC64; MAAEVSVKRR HVHKFGGSSL ADPVCYRRVA AIVEQQSGGN ELVVVSAAGK TTNRLIQLVE LAEGGDEAAG EAHTALHAYQ QSLIDGLLEG DLQADLRAQL AEDFRTIART LERQFDRFER NGLLAFGEVW SARLLAALLT QRGNPTLWLD ARSFLRAEDG PLIRVDHALS SELLKARLAE HDGRIVVTGF IAADLEGRSL LLGRNGSDYS ASLLAALADG ESTTIWSDVA GVYSADPRRV KEARLLERLS LAEANELARL GSSVLHSRTL QPVVDSRQRL TLRCSYNPDE GCTHILRRAP RSGGARIVSS VDQIALIELK VLPEGEFERA AAAIEAYLAR HRIQPLTAQR QPDRRMLRLA YTLEVASGAY DLLRDYQLEG GFTGLILKEG YSLVALVGAG VTENAEQCHR FYQLTADQPV EFVQAAKDSL SLVAVLRQIV LEPLLIALHG ALFSRPTRVG LVVFGKGNIG GHWLSLYNRE RQRLEQELNL ALTLYGVYGS EGGWLDEEGL DPLRVQEASN PAPLIWPELL GQLEQHSFDA LIALDLTASE TVSRYYPDLA QLGIHLIAAN KFAGAAESEF YQRVKQSCRD HQVQWRYNAT VGAGLPVQSS IQMLRQSGDR IHGVSGIFSG TLSWLFQQYD GCRPFSELVE EAWQHGLTEP DPREDLSGQD VRRKLLILAR ESGYEIDAND IELENLVPVP LRKLGPDQFM DRLKELDGPI LSAFESARRL GKVLRYVARF EHDGKARVGL ESLEPHHPFA NLLPCDNIFA IESDSYRTNP LVIQGPGAGR EVTAAAIQYD LWQICASL //