ID M9PI63_DROME Unreviewed; 2839 AA. AC M9PI63; DT 26-JUN-2013, integrated into UniProtKB/TrEMBL. DT 26-JUN-2013, sequence version 1. DT 18-SEP-2019, entry version 52. DE SubName: Full=Pericentrin-like protein, isoform L {ECO:0000313|EMBL:AGB94556.1}; GN Name=Plp {ECO:0000313|EMBL:AGB94556.1, GN ECO:0000313|FlyBase:FBgn0086690}; GN Synonyms=AKAP450 {ECO:0000313|EMBL:AGB94556.1}, CG13459 GN {ECO:0000313|EMBL:AGB94556.1}, CG18648 {ECO:0000313|EMBL:AGB94556.1}, GN CG6735 {ECO:0000313|EMBL:AGB94556.1}, CP309 GN {ECO:0000313|EMBL:AGB94556.1}, Cp309 {ECO:0000313|EMBL:AGB94556.1}, GN cp309 {ECO:0000313|EMBL:AGB94556.1}, D-PLP GN {ECO:0000313|EMBL:AGB94556.1}, D-Plp {ECO:0000313|EMBL:AGB94556.1}, GN d-plp {ECO:0000313|EMBL:AGB94556.1}, Dmel\CG33957 GN {ECO:0000313|EMBL:AGB94556.1}, DPLP {ECO:0000313|EMBL:AGB94556.1}, GN DPlp {ECO:0000313|EMBL:AGB94556.1}, Dplp GN {ECO:0000313|EMBL:AGB94556.1}, dPLP {ECO:0000313|EMBL:AGB94556.1}, GN dplp {ECO:0000313|EMBL:AGB94556.1}, l(3)s2172 GN {ECO:0000313|EMBL:AGB94556.1}, PACT {ECO:0000313|EMBL:AGB94556.1}, GN PCNT {ECO:0000313|EMBL:AGB94556.1}, PLP {ECO:0000313|EMBL:AGB94556.1}, GN plp {ECO:0000313|EMBL:AGB94556.1}, pPlp {ECO:0000313|EMBL:AGB94556.1}; GN ORFNames=CG33957 {ECO:0000313|EMBL:AGB94556.1, GN ECO:0000313|FlyBase:FBgn0086690}, Dmel_CG33957 GN {ECO:0000313|EMBL:AGB94556.1}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AGB94556.1, ECO:0000313|Proteomes:UP000000803}; RN [1] {ECO:0000313|EMBL:AGB94556.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., RA Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., RA Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] {ECO:0000313|EMBL:AGB94556.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] {ECO:0000313|EMBL:AGB94556.1, ECO:0000313|Proteomes:UP000000803} RP GENOME REANNOTATION. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [4] {ECO:0000313|EMBL:AGB94556.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002). RN [5] {ECO:0000313|EMBL:AGB94556.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [6] {ECO:0000313|EMBL:AGB94556.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [7] {ECO:0000313|EMBL:AGB94556.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [8] {ECO:0000313|EMBL:AGB94556.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014296; AGB94556.1; -; Genomic_DNA. DR RefSeq; NP_001261863.1; NM_001274934.1. DR SMR; M9PI63; -. DR GeneID; 3772382; -. DR CTD; 3772382; -. DR FlyBase; FBgn0086690; Plp. DR eggNOG; ENOG410IJHT; Eukaryota. DR eggNOG; ENOG4110FJZ; LUCA. DR ChiTaRS; Plp; fly. DR GenomeRNAi; 3772382; -. DR Proteomes; UP000000803; Chromosome 3L. DR Bgee; FBgn0086690; Expressed in 31 organ(s), highest expression level in embryonic/larval hemocyte (Drosophila). DR ExpressionAtlas; M9PI63; baseline and differential. DR GO; GO:0005814; C:centriole; IDA:FlyBase. DR GO; GO:0060090; F:molecular adaptor activity; IEA:InterPro. DR GO; GO:0007098; P:centrosome cycle; IMP:FlyBase. DR GO; GO:0060285; P:cilium-dependent cell motility; IMP:FlyBase. DR GO; GO:0007020; P:microtubule nucleation; IDA:FlyBase. DR GO; GO:0007605; P:sensory perception of sound; IMP:FlyBase. DR GO; GO:0007165; P:signal transduction; IEA:InterPro. DR InterPro; IPR028745; AKAP9/Pericentrin. DR InterPro; IPR019528; PACT_domain. DR PANTHER; PTHR44981; PTHR44981; 2. DR Pfam; PF10495; PACT_coil_coil; 1. PE 1: Evidence at protein level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000000803}; KW Proteomics identification {ECO:0000213|PeptideAtlas:M9PI63}; KW Reference proteome {ECO:0000313|Proteomes:UP000000803}. FT DOMAIN 2648 2720 PACT_coil_coil. {ECO:0000259|Pfam: FT PF10495}. FT REGION 87 108 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 151 214 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 242 266 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 288 389 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 569 589 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 644 664 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 906 975 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 1017 1040 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 1355 1379 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 1671 1706 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 1907 1944 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 2260 2288 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 2372 2407 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 2422 2442 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COILED 708 735 {ECO:0000256|SAM:Coils}. FT COILED 854 874 {ECO:0000256|SAM:Coils}. FT COILED 880 900 {ECO:0000256|SAM:Coils}. FT COILED 997 1017 {ECO:0000256|SAM:Coils}. FT COILED 1073 1093 {ECO:0000256|SAM:Coils}. FT COILED 1136 1156 {ECO:0000256|SAM:Coils}. FT COILED 1390 1438 {ECO:0000256|SAM:Coils}. FT COILED 1513 1540 {ECO:0000256|SAM:Coils}. FT COILED 1733 1788 {ECO:0000256|SAM:Coils}. FT COILED 1790 1838 {ECO:0000256|SAM:Coils}. FT COILED 1850 1870 {ECO:0000256|SAM:Coils}. FT COILED 2072 2138 {ECO:0000256|SAM:Coils}. FT COILED 2150 2219 {ECO:0000256|SAM:Coils}. FT COILED 2291 2318 {ECO:0000256|SAM:Coils}. FT COILED 2510 2544 {ECO:0000256|SAM:Coils}. FT COMPBIAS 91 108 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 317 338 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 352 366 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 575 589 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 1017 1031 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 1671 1690 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 1912 1928 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 2372 2391 Polar. {ECO:0000256|SAM:MobiDB-lite}. SQ SEQUENCE 2839 AA; 320506 MW; 690F5D1B8B6B1754 CRC64; MNLYTIYDWI TSLLRPHGAS VSYKAIEAAT LEELPATSVA TATSTAATSR ATGGAAATCV DVEFIPTLNI IFEKPTSSSE QLQCAEKSEH VAGGVSDKEP ADDCDSDNDS TRTYIISRSS WTGVTSSSST PYAVTSTDTA ELLRRQNNLS LTEEDQSVSS FSIEQPTSSI TIEMADQRTT TTTTTTATTA TTPSSANILA TTATTTTTTS SSIEEEIEEA IEISEVEEQL NTPLESLSEA AAYARPKDEQ SSAKSLSSNP AEDEDADEFR IDDAQLSGGQ LAQHFLVDED ESEEGSDLPA ASKVEVSLSS NDDDFDISLP LEQRKPVHSL HEDDESVDQS LSNQSTTDDV SELVEEPVHE MDDKTDGSAA ISASAPQETQ VDESQITDEQ DHSMEEIVAT NESIEVTYEA EETVNTSQKQ DLITDLDEES EDQVHVDNRP TSTLQALKLP ALQQPQIVER KAATALTTLR LQADVLEPLE LTILEMDDDE NEEDDDDEES SLQLMKLRLM AMNQQMIVDN APKLSPTEAE QTQVTSSSNN LEIKQMERVP LTEFSKDVLE DITEESERLL SMSTTMEEEQ DPPSLSLDES KTLLQPGAHK TGGSSSSLVS LNMLKQLEAK VQELHTQLET KDNCLASLNL QLETARRESS AGPASARDSS SLMTNSTEYR TLQEELGGPT LDIYVEMSRR DELIAKLTDS LQQSLNVRDK LQVDADRLGG EVQNLRRQLQ ETLDAVKRSS AVWPDQECNP GQRISEISMD LISESDDDLD RHFLTDNEER GSRSSKERQL TQLQTNEELG LQASNPEWTP TFSKQIEQFH TYLLPTEQRI FQMVQRKFDD YLNQQITLCR DLGAQELKIA RDQWESEKLT SEQNQQAAHA KQMEDLRKYF EHKCADLEKQ FSDDVFSHKS QHQTGDSSSE CSEVDQLPEE GAAAVSSKEP SPRKRKRAEL LLSPSHRQMT PCGLDSLGEN TGKTEKDNTA DIADLKIFYQ THIKELKRAH EDQVRKLSDR IKFYERQQGD DDYKPATESP ERTCPDQESA GGVANTSLII IDEDELNFNN ESQVIQRIIE EYEKRLQEQL ALARQDIATE LEQQIKSLLS ENTVDDQHWP KELILLREKF TAKSQLEITQ LNIKHAEEMS RLKLEFEKQL NRKNKRHLTF DAARDLEQVI CERDGLRELS KSFRSVLCRL AKCVAHCEED LNATLSEEVQ RLLFHSRSQD GGDDLEATIS SSLNNTKHML RVPDVHSLLE VVEDPSLVQF IDSKSNEEPS EDFDLNDCLE RLKSEASYLL HLSEDLHKQR THDESSEHLD EPEKQEHELC CEAEDGLKTT GAVNQQVLSK FLRTNSLNDQ QMGVANQRKN SNPEAGKTHS SLPPDLQEHA GNASELSFQL VQLKNRLIKS EADRQNLQQQ LSRTIDRNAE LGQELQALRD QLSQLNSLNH TDYNEGYGLG TMKSLQEQGL DQSSASFLAL QERARHLLSS SPVKEQPSRD HGNSTVILLQ MIEDFCREGD KVVEFSKKDR EDLQSQYAQL ESQFREVNQQ LCESNAKRDK FEVELKASID KIFVLREIIS ELETQVQTKA LNEEVLAEKA QQLEEYVSLQ MRDNDILQQE VHSLKTDIGE GYQSRIRVLE EKLKQSGPTA EQGVVLSQVA EKLRDIETTL DQKTKALESL HNSNATSNSA SLSVTEDVSI HGSKEPTAVG SPSHPSLTVE GVQRVTEKLD RHTRVEEAAI KRIRDLEMQV HQMRAGCVEL QHERDTLQGR MEEQTQRIST LQNRLEEQRQ RAEQLHRTGT SDLNTRVHEL QGEVQNLYEQ LAARDKQMAN MRQQLQRSKE EITRLETEVE VRTQPDRSLV NKLQAEVQQK GAEIVKLKDK IRTEMINRLA IPDLMETMLA DKNDEIDHLR DQLEAKEKEL QASQQEASQI SSPSGAAGKQ EGSGGKLSAR TLSDIGSITE FPEPDVERRA AMRSLTALQM SEGAGGFLHQ TMETSKEAVA NLTHKRTDDL SGFIVPYPVN TFEHPHYFQA LGVTAQSTDG LTPGLVPRQI NFSNLTEDSK LKTTSLLMHT PELPRPTTPP EIHQLRVKLS DLQTEKQRQQ SELEKKLQDL QKELEQEKEK LSRQAQTLQS YEESEAKYRL RIENLESKVL ETAAQAASDR ENLRKELNCV SAAHEQCENA AAARKRELEK LNSEVKVKAD QLHAALRRCA DLELQVLTLE RDLERLKNSD NSSKQYSVDE IAQQVEKELN YSAQLDSNIL KAIESEEENN LDKKLQKGVQ TEEETLPGTG NGTDDENFTG ERELLNQLEA LRAQLAVERE QCEAMSKELL GEKQHSQDIQ EQDVIIIEAM RKRLETALDA EDELHKQLDQ ERERCERLQT QLTSLQRAES RRNSSLLLKS PGDSPRKSPR ADFESELGDR LRSEIKLLVA QNERERERSA DAQRSSERER QRYEKELQER VAYCERLKQE MEKLSRDKES AETELEHFNE RLTLQASEIE SLEARLVTLQ EAETRRANTR TRQHQENVKL QAEIHELKSK LLAAEAARDC LDQKVTQLRF DVSRSGQREA KLAEALAQAN DRLAHSTDDN VPAQFMQKMK EINALLAENT QENRQMAETV QFLVGERIAL QKKCEELGGA GNTNVTELEE RCRQLIGRYL RVESHRKALV YQKRYLKLTL EGYQASEQLA LQNLRGGAEQ PPQRNIKKKF KTVALAIIAI QRIKYIGRIW HTGKRIVSKS VFTITQQRSP GLNLNVAPPQ SPLPGPNSNL PTNNNNLMGR LSYAPLSPPM VNFSTVQPIM LPSDFTLQAP TTSLQTTIAN NNSENTLPSL ARLDWPTMQK PKRAHARHH //