ID M9PFV9_DROME Unreviewed; 313 AA. AC M9PFV9; DT 26-JUN-2013, integrated into UniProtKB/TrEMBL. DT 26-JUN-2013, sequence version 1. DT 16-OCT-2013, entry version 4. DE SubName: Full=RNA polymerase II elongation factor, isoform B; GN Name=TfIIS; ORFNames=CG3710, Dmel_CG3710; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., RA Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., RA Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., RA Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] RP GENOME REANNOTATION. RC STRAIN=Berkeley; RX PubMed=12537572; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014134; AGB92992.1; -; Genomic_DNA. DR RefSeq; NP_001260457.1; NM_001273528.1. DR RefSeq; NP_476967.1; NM_057619.4. DR UniGene; Dm.3045; -. DR ProteinModelPortal; M9PFV9; -. DR SMR; M9PFV9; 3-93, 151-313. DR GeneID; 34883; -. DR KEGG; dme:Dmel_CG3710; -. DR CTD; 34883; -. DR FlyBase; FBgn0010422; TfIIS. DR KO; K03145; -. DR OMA; LECGKCK; -. DR PhylomeDB; M9PFV9; -. DR GO; GO:0005634; C:nucleus; IEA:InterPro. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0032784; P:regulation of DNA-dependent transcription, elongation; IEA:InterPro. DR GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro. DR GO; GO:0006351; P:transcription, DNA-dependent; IEA:InterPro. DR Gene3D; 1.10.472.30; -; 1. DR Gene3D; 1.20.930.10; -; 1. DR InterPro; IPR016492; TF_IIS-rel. DR InterPro; IPR003617; TFIIS/CRSP70_N_sub. DR InterPro; IPR003618; TFIIS_cen_dom. DR InterPro; IPR017923; TFIIS_N. DR InterPro; IPR017890; TFS2M. DR InterPro; IPR006289; TFSII. DR InterPro; IPR001222; Znf_TFIIS. DR Pfam; PF08711; Med26; 1. DR Pfam; PF01096; TFIIS_C; 1. DR Pfam; PF07500; TFIIS_M; 1. DR PIRSF; PIRSF006704; TF_IIS; 1. DR SMART; SM00510; TFS2M; 1. DR SMART; SM00509; TFS2N; 1. DR SMART; SM00440; ZnF_C2C2; 1. DR SUPFAM; SSF46942; SSF46942; 1. DR SUPFAM; SSF47676; SSF47676; 1. DR TIGRFAMs; TIGR01385; TFSII; 1. DR PROSITE; PS51321; TFIIS_CENTRAL; 1. DR PROSITE; PS51319; TFIIS_N; 1. DR PROSITE; PS00466; ZF_TFIIS_1; 1. DR PROSITE; PS51133; ZF_TFIIS_2; 1. PE 4: Predicted; KW Complete proteome; Elongation factor; Protein biosynthesis; KW Reference proteome. SQ SEQUENCE 313 AA; 34300 MW; 9DC7D99D71BD3DA3 CRC64; MSVEEEVFRI QKKMSKMASD GTGQDQALDL LKALQTLNIN LDILTKTRIG MTVNELRKSS KDDEVIALAK TLIKNWKRFL ASPAPTTPNN SSAKEGSSNN SSASKSTSAA KSSSSISGKD KSSSSSSSKD KEKKGSTSSS QTSFPSGGMT DAVRIKCREM LATALKIGEV PEGCGEPEEM AAELEDAIYS EFNNTDMKYK NRIRSRVANL KDPKNPGLRG NFMCGAVTAK QLAKMTPEEM ASDEMKKLRE KFVKEAINDA QLATVQGTKT DLLKCAKCKK RNCTYNQLQT RSADEPMTTF VMCNECGNRW KFC //