ID M9NFV3_DROME Unreviewed; 2767 AA. AC M9NFV3; DT 26-JUN-2013, integrated into UniProtKB/TrEMBL. DT 26-JUN-2013, sequence version 1. DT 18-SEP-2019, entry version 52. DE SubName: Full=Pericentrin-like protein, isoform D {ECO:0000313|EMBL:AFH04432.1}; GN Name=Plp {ECO:0000313|EMBL:AFH04432.1, GN ECO:0000313|FlyBase:FBgn0086690}; GN Synonyms=AKAP450 {ECO:0000313|EMBL:AFH04432.1}, CG13459 GN {ECO:0000313|EMBL:AFH04432.1}, CG18648 {ECO:0000313|EMBL:AFH04432.1}, GN CG6735 {ECO:0000313|EMBL:AFH04432.1}, CP309 GN {ECO:0000313|EMBL:AFH04432.1}, Cp309 {ECO:0000313|EMBL:AFH04432.1}, GN cp309 {ECO:0000313|EMBL:AFH04432.1}, D-PLP GN {ECO:0000313|EMBL:AFH04432.1}, D-Plp {ECO:0000313|EMBL:AFH04432.1}, GN d-plp {ECO:0000313|EMBL:AFH04432.1}, Dmel\CG33957 GN {ECO:0000313|EMBL:AFH04432.1}, DPLP {ECO:0000313|EMBL:AFH04432.1}, GN DPlp {ECO:0000313|EMBL:AFH04432.1}, Dplp GN {ECO:0000313|EMBL:AFH04432.1}, dPLP {ECO:0000313|EMBL:AFH04432.1}, GN dplp {ECO:0000313|EMBL:AFH04432.1}, l(3)s2172 GN {ECO:0000313|EMBL:AFH04432.1}, PACT {ECO:0000313|EMBL:AFH04432.1}, GN PCNT {ECO:0000313|EMBL:AFH04432.1}, PLP {ECO:0000313|EMBL:AFH04432.1}, GN plp {ECO:0000313|EMBL:AFH04432.1}, pPlp {ECO:0000313|EMBL:AFH04432.1}; GN ORFNames=CG33957 {ECO:0000313|EMBL:AFH04432.1, GN ECO:0000313|FlyBase:FBgn0086690}, Dmel_CG33957 GN {ECO:0000313|EMBL:AFH04432.1}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803}; RN [1] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., RA Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., RA Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP GENOME REANNOTATION. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [4] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002). RN [5] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [6] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [7] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [8] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014296; AFH04432.1; -; Genomic_DNA. DR RefSeq; NP_001246761.1; NM_001259832.1. DR SMR; M9NFV3; -. DR GeneID; 3772382; -. DR CTD; 3772382; -. DR FlyBase; FBgn0086690; Plp. DR eggNOG; ENOG410IJHT; Eukaryota. DR eggNOG; ENOG4110FJZ; LUCA. DR ChiTaRS; Plp; fly. DR GenomeRNAi; 3772382; -. DR Proteomes; UP000000803; Chromosome 3L. DR Bgee; FBgn0086690; Expressed in 31 organ(s), highest expression level in embryonic/larval hemocyte (Drosophila). DR ExpressionAtlas; M9NFV3; baseline and differential. DR GO; GO:0005814; C:centriole; IDA:FlyBase. DR GO; GO:0060090; F:molecular adaptor activity; IEA:InterPro. DR GO; GO:0007098; P:centrosome cycle; IMP:FlyBase. DR GO; GO:0060285; P:cilium-dependent cell motility; IMP:FlyBase. DR GO; GO:0007020; P:microtubule nucleation; IDA:FlyBase. DR GO; GO:0007605; P:sensory perception of sound; IMP:FlyBase. DR GO; GO:0007165; P:signal transduction; IEA:InterPro. DR InterPro; IPR028745; AKAP9/Pericentrin. DR InterPro; IPR019528; PACT_domain. DR PANTHER; PTHR44981; PTHR44981; 3. DR Pfam; PF10495; PACT_coil_coil; 1. PE 1: Evidence at protein level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000000803}; KW Proteomics identification {ECO:0000213|PeptideAtlas:M9NFV3}; KW Reference proteome {ECO:0000313|Proteomes:UP000000803}. FT DOMAIN 2576 2648 PACT_coil_coil. {ECO:0000259|Pfam: FT PF10495}. FT REGION 87 108 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 151 214 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 242 266 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 288 389 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 569 589 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 644 664 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 906 975 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 1283 1307 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 1599 1634 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 1835 1872 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 2188 2216 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 2300 2335 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 2350 2370 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COILED 708 735 {ECO:0000256|SAM:Coils}. FT COILED 854 874 {ECO:0000256|SAM:Coils}. FT COILED 880 900 {ECO:0000256|SAM:Coils}. FT COILED 997 1017 {ECO:0000256|SAM:Coils}. FT COILED 1064 1084 {ECO:0000256|SAM:Coils}. FT COILED 1318 1366 {ECO:0000256|SAM:Coils}. FT COILED 1441 1468 {ECO:0000256|SAM:Coils}. FT COILED 1661 1716 {ECO:0000256|SAM:Coils}. FT COILED 1718 1766 {ECO:0000256|SAM:Coils}. FT COILED 1778 1798 {ECO:0000256|SAM:Coils}. FT COILED 2000 2066 {ECO:0000256|SAM:Coils}. FT COILED 2078 2147 {ECO:0000256|SAM:Coils}. FT COILED 2219 2246 {ECO:0000256|SAM:Coils}. FT COILED 2438 2472 {ECO:0000256|SAM:Coils}. FT COMPBIAS 91 108 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 317 338 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 352 366 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 575 589 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 1599 1618 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 1840 1856 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 2300 2319 Polar. {ECO:0000256|SAM:MobiDB-lite}. SQ SEQUENCE 2767 AA; 312353 MW; 69F0DCE70149C867 CRC64; MNLYTIYDWI TSLLRPHGAS VSYKAIEAAT LEELPATSVA TATSTAATSR ATGGAAATCV DVEFIPTLNI IFEKPTSSSE QLQCAEKSEH VAGGVSDKEP ADDCDSDNDS TRTYIISRSS WTGVTSSSST PYAVTSTDTA ELLRRQNNLS LTEEDQSVSS FSIEQPTSSI TIEMADQRTT TTTTTTATTA TTPSSANILA TTATTTTTTS SSIEEEIEEA IEISEVEEQL NTPLESLSEA AAYARPKDEQ SSAKSLSSNP AEDEDADEFR IDDAQLSGGQ LAQHFLVDED ESEEGSDLPA ASKVEVSLSS NDDDFDISLP LEQRKPVHSL HEDDESVDQS LSNQSTTDDV SELVEEPVHE MDDKTDGSAA ISASAPQETQ VDESQITDEQ DHSMEEIVAT NESIEVTYEA EETVNTSQKQ DLITDLDEES EDQVHVDNRP TSTLQALKLP ALQQPQIVER KAATALTTLR LQADVLEPLE LTILEMDDDE NEEDDDDEES SLQLMKLRLM AMNQQMIVDN APKLSPTEAE QTQVTSSSNN LEIKQMERVP LTEFSKDVLE DITEESERLL SMSTTMEEEQ DPPSLSLDES KTLLQPGAHK TGGSSSSLVS LNMLKQLEAK VQELHTQLET KDNCLASLNL QLETARRESS AGPASARDSS SLMTNSTEYR TLQEELGGPT LDIYVEMSRR DELIAKLTDS LQQSLNVRDK LQVDADRLGG EVQNLRRQLQ ETLDAVKRSS AVWPDQECNP GQRISEISMD LISESDDDLD RHFLTDNEER GSRSSKERQL TQLQTNEELG LQASNPEWTP TFSKQIEQFH TYLLPTEQRI FQMVQRKFDD YLNQQITLCR DLGAQELKIA RDQWESEKLT SEQNQQAAHA KQMEDLRKYF EHKCADLEKQ FSDDVFSHKS QHQTGDSSSE CSEVDQLPEE GAAAVSSKEP SPRKRKRAEL LLSPSHRQMT PCGLDSLGEN TGKTEKDNTA DIADLKIFYQ THIKELKRAH EDQVRKLSDR IKFYERQQGD DDYKSLLSEN TVDDQHWPKE LILLREKFTA KSQLEITQLN IKHAEEMSRL KLEFEKQLNR KNKRHLTFDA ARDLEQVICE RDGLRELSKS FRSVLCRLAK CVAHCEEDLN ATLSEEVQRL LFHSRSQDGG DDLEATISSS LNNTKHMLRV PDVHSLLEVV EDPSLVQFID SKSNEEPSED FDLNDCLERL KSEASYLLHL SEDLHKQRTH DESSEHLDEP EKQEHELCCE AEDGLKTTGA VNQQVLSKFL RTNSLNDQQM GVANQRKNSN PEAGKTHSSL PPDLQEHAGN ASELSFQLVQ LKNRLIKSEA DRQNLQQQLS RTIDRNAELG QELQALRDQL SQLNSLNHTD YNEGYGLGTM KSLQEQGLDQ SSASFLALQE RARHLLSSSP VKEQPSRDHG NSTVILLQMI EDFCREGDKV VEFSKKDRED LQSQYAQLES QFREVNQQLC ESNAKRDKFE VELKASIDKI FVLREIISEL ETQVQTKALN EEVLAEKAQQ LEEYVSLQMR DNDILQQEVH SLKTDIGEGY QSRIRVLEEK LKQSGPTAEQ GVVLSQVAEK LRDIETTLDQ KTKALESLHN SNATSNSASL SVTEDVSIHG SKEPTAVGSP SHPSLTVEGV QRVTEKLDRH TRVEEAAIKR IRDLEMQVHQ MRAGCVELQH ERDTLQGRME EQTQRISTLQ NRLEEQRQRA EQLHRTGTSD LNTRVHELQG EVQNLYEQLA ARDKQMANMR QQLQRSKEEI TRLETEVEVR TQPDRSLVNK LQAEVQQKGA EIVKLKDKIR TEMINRLAIP DLMETMLADK NDEIDHLRDQ LEAKEKELQA SQQEASQISS PSGAAGKQEG SGGKLSARTL SDIGSITEFP EPDVERRAAM RSLTALQMSE GAGGFLHQTM ETSKEAVANL THKRTDDLSG FIVPYPVNTF EHPHYFQALG VTAQSTDGLT PGLVPRQINF SNLTEDSKLK TTSLLMHTPE LPRPTTPPEI HQLRVKLSDL QTEKQRQQSE LEKKLQDLQK ELEQEKEKLS RQAQTLQSYE ESEAKYRLRI ENLESKVLET AAQAASDREN LRKELNCVSA AHEQCENAAA ARKRELEKLN SEVKVKADQL HAALRRCADL ELQVLTLERD LERLKNSDNS SKQYSVDEIA QQVEKELNYS AQLDSNILKA IESEEENNLD KKLQKGVQTE EETLPGTGNG TDDENFTGER ELLNQLEALR AQLAVEREQC EAMSKELLGE KQHSQDIQEQ DVIIIEAMRK RLETALDAED ELHKQLDQER ERCERLQTQL TSLQRAESRR NSSLLLKSPG DSPRKSPRAD FESELGDRLR SEIKLLVAQN ERERERSADA QRSSERERQR YEKELQERVA YCERLKQEME KLSRDKESAE TELEHFNERL TLQASEIESL EARLVTLQEA ETRRANTRTR QHQENVKLQA EIHELKSKLL AAEAARDCLD QKVTQLRFDV SRSGQREAKL AEALAQANDR LAHSTDDNVP AQFMQKMKEI NALLAENTQE NRQMAETVQF LVGERIALQK KCEELGGAGN TNVTELEERC RQLIGRYLRV ESHRKALVYQ KRYLKLTLEG YQASEQLALQ NLRGGAEQPP QRNIKKKFKT VALAIIAIQR IKYIGRIWHT GKRIVSKSVF TITQQRSPGL NLNVAPPQSP LPGPNSNLPT NNNNLMGRLS YAPLSPPMVN FSTVQPIMLP SDFTLQAPTT SLQTTIANNN SENTLPSLAR LDWPTMQKPK RAHARHH //