ID M9NFV3_DROME Unreviewed; 2767 AA. AC M9NFV3; DT 26-JUN-2013, integrated into UniProtKB/TrEMBL. DT 26-JUN-2013, sequence version 1. DT 18-JAN-2017, entry version 29. DE SubName: Full=Pericentrin-like protein, isoform D {ECO:0000313|EMBL:AFH04432.1}; GN Name=Plp {ECO:0000313|EMBL:AFH04432.1, GN ECO:0000313|FlyBase:FBgn0086690}; GN ORFNames=CG33957 {ECO:0000313|FlyBase:FBgn0086690}, Dmel_CG33957 GN {ECO:0000313|EMBL:AFH04432.1}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803}; RN [1] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., RA Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., RA Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP GENOME REANNOTATION. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [4] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002). RN [5] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [6] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [7] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [8] {ECO:0000313|EMBL:AFH04432.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014296; AFH04432.1; -; Genomic_DNA. DR RefSeq; NP_001246761.1; NM_001259832.1. DR UniGene; Dm.14930; -. DR SMR; M9NFV3; -. DR STRING; 7227.FBpp0297121; -. DR PaxDb; M9NFV3; -. DR EnsemblMetazoa; FBtr0305977; FBpp0297119; FBgn0086690. DR GeneID; 3772382; -. DR CTD; 3772382; -. DR FlyBase; FBgn0086690; Plp. DR eggNOG; ENOG410IJHT; Eukaryota. DR eggNOG; ENOG4110FJZ; LUCA. DR OrthoDB; EOG091G002K; -. DR ChiTaRS; cp309; fly. DR GenomeRNAi; 3772382; -. DR Proteomes; UP000000803; Chromosome 3L. DR ExpressionAtlas; M9NFV3; differential. DR GO; GO:0005814; C:centriole; IDA:FlyBase. DR GO; GO:0051297; P:centrosome organization; IMP:FlyBase. DR GO; GO:0060285; P:cilium-dependent cell motility; IMP:FlyBase. DR GO; GO:0048598; P:embryonic morphogenesis; IMP:FlyBase. DR GO; GO:0007020; P:microtubule nucleation; IDA:FlyBase. DR GO; GO:0007605; P:sensory perception of sound; IMP:FlyBase. DR InterPro; IPR019528; PACT_domain. DR Pfam; PF10495; PACT_coil_coil; 1. PE 1: Evidence at protein level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000000803}; KW Proteomics identification {ECO:0000213|PeptideAtlas:M9NFV3}; KW Reference proteome {ECO:0000313|Proteomes:UP000000803}. FT DOMAIN 2576 2648 PACT_coil_coil. {ECO:0000259|Pfam: FT PF10495}. FT COILED 614 648 {ECO:0000256|SAM:Coils}. FT COILED 708 735 {ECO:0000256|SAM:Coils}. FT COILED 1318 1366 {ECO:0000256|SAM:Coils}. FT COILED 1441 1468 {ECO:0000256|SAM:Coils}. FT COILED 1661 1716 {ECO:0000256|SAM:Coils}. FT COILED 1718 1766 {ECO:0000256|SAM:Coils}. FT COILED 1817 1848 {ECO:0000256|SAM:Coils}. FT COILED 2000 2066 {ECO:0000256|SAM:Coils}. FT COILED 2078 2147 {ECO:0000256|SAM:Coils}. FT COILED 2219 2246 {ECO:0000256|SAM:Coils}. FT COILED 2265 2306 {ECO:0000256|SAM:Coils}. FT COILED 2368 2430 {ECO:0000256|SAM:Coils}. FT COILED 2438 2472 {ECO:0000256|SAM:Coils}. SQ SEQUENCE 2767 AA; 312353 MW; 69F0DCE70149C867 CRC64; MNLYTIYDWI TSLLRPHGAS VSYKAIEAAT LEELPATSVA TATSTAATSR ATGGAAATCV DVEFIPTLNI IFEKPTSSSE QLQCAEKSEH VAGGVSDKEP ADDCDSDNDS TRTYIISRSS WTGVTSSSST PYAVTSTDTA ELLRRQNNLS LTEEDQSVSS FSIEQPTSSI TIEMADQRTT TTTTTTATTA TTPSSANILA TTATTTTTTS SSIEEEIEEA IEISEVEEQL NTPLESLSEA AAYARPKDEQ SSAKSLSSNP AEDEDADEFR IDDAQLSGGQ LAQHFLVDED ESEEGSDLPA ASKVEVSLSS NDDDFDISLP LEQRKPVHSL HEDDESVDQS LSNQSTTDDV SELVEEPVHE MDDKTDGSAA ISASAPQETQ VDESQITDEQ DHSMEEIVAT NESIEVTYEA EETVNTSQKQ DLITDLDEES EDQVHVDNRP TSTLQALKLP ALQQPQIVER KAATALTTLR LQADVLEPLE LTILEMDDDE NEEDDDDEES SLQLMKLRLM AMNQQMIVDN APKLSPTEAE QTQVTSSSNN LEIKQMERVP LTEFSKDVLE DITEESERLL SMSTTMEEEQ DPPSLSLDES KTLLQPGAHK TGGSSSSLVS LNMLKQLEAK VQELHTQLET KDNCLASLNL QLETARRESS AGPASARDSS SLMTNSTEYR TLQEELGGPT LDIYVEMSRR DELIAKLTDS LQQSLNVRDK LQVDADRLGG EVQNLRRQLQ ETLDAVKRSS AVWPDQECNP GQRISEISMD LISESDDDLD RHFLTDNEER GSRSSKERQL TQLQTNEELG LQASNPEWTP TFSKQIEQFH TYLLPTEQRI FQMVQRKFDD YLNQQITLCR DLGAQELKIA RDQWESEKLT SEQNQQAAHA KQMEDLRKYF EHKCADLEKQ FSDDVFSHKS QHQTGDSSSE CSEVDQLPEE GAAAVSSKEP SPRKRKRAEL LLSPSHRQMT PCGLDSLGEN TGKTEKDNTA DIADLKIFYQ THIKELKRAH EDQVRKLSDR IKFYERQQGD DDYKSLLSEN TVDDQHWPKE LILLREKFTA KSQLEITQLN IKHAEEMSRL KLEFEKQLNR KNKRHLTFDA ARDLEQVICE RDGLRELSKS FRSVLCRLAK CVAHCEEDLN ATLSEEVQRL LFHSRSQDGG DDLEATISSS LNNTKHMLRV PDVHSLLEVV EDPSLVQFID SKSNEEPSED FDLNDCLERL KSEASYLLHL SEDLHKQRTH DESSEHLDEP EKQEHELCCE AEDGLKTTGA VNQQVLSKFL RTNSLNDQQM GVANQRKNSN PEAGKTHSSL PPDLQEHAGN ASELSFQLVQ LKNRLIKSEA DRQNLQQQLS RTIDRNAELG QELQALRDQL SQLNSLNHTD YNEGYGLGTM KSLQEQGLDQ SSASFLALQE RARHLLSSSP VKEQPSRDHG NSTVILLQMI EDFCREGDKV VEFSKKDRED LQSQYAQLES QFREVNQQLC ESNAKRDKFE VELKASIDKI FVLREIISEL ETQVQTKALN EEVLAEKAQQ LEEYVSLQMR DNDILQQEVH SLKTDIGEGY QSRIRVLEEK LKQSGPTAEQ GVVLSQVAEK LRDIETTLDQ KTKALESLHN SNATSNSASL SVTEDVSIHG SKEPTAVGSP SHPSLTVEGV QRVTEKLDRH TRVEEAAIKR IRDLEMQVHQ MRAGCVELQH ERDTLQGRME EQTQRISTLQ NRLEEQRQRA EQLHRTGTSD LNTRVHELQG EVQNLYEQLA ARDKQMANMR QQLQRSKEEI TRLETEVEVR TQPDRSLVNK LQAEVQQKGA EIVKLKDKIR TEMINRLAIP DLMETMLADK NDEIDHLRDQ LEAKEKELQA SQQEASQISS PSGAAGKQEG SGGKLSARTL SDIGSITEFP EPDVERRAAM RSLTALQMSE GAGGFLHQTM ETSKEAVANL THKRTDDLSG FIVPYPVNTF EHPHYFQALG VTAQSTDGLT PGLVPRQINF SNLTEDSKLK TTSLLMHTPE LPRPTTPPEI HQLRVKLSDL QTEKQRQQSE LEKKLQDLQK ELEQEKEKLS RQAQTLQSYE ESEAKYRLRI ENLESKVLET AAQAASDREN LRKELNCVSA AHEQCENAAA ARKRELEKLN SEVKVKADQL HAALRRCADL ELQVLTLERD LERLKNSDNS SKQYSVDEIA QQVEKELNYS AQLDSNILKA IESEEENNLD KKLQKGVQTE EETLPGTGNG TDDENFTGER ELLNQLEALR AQLAVEREQC EAMSKELLGE KQHSQDIQEQ DVIIIEAMRK RLETALDAED ELHKQLDQER ERCERLQTQL TSLQRAESRR NSSLLLKSPG DSPRKSPRAD FESELGDRLR SEIKLLVAQN ERERERSADA QRSSERERQR YEKELQERVA YCERLKQEME KLSRDKESAE TELEHFNERL TLQASEIESL EARLVTLQEA ETRRANTRTR QHQENVKLQA EIHELKSKLL AAEAARDCLD QKVTQLRFDV SRSGQREAKL AEALAQANDR LAHSTDDNVP AQFMQKMKEI NALLAENTQE NRQMAETVQF LVGERIALQK KCEELGGAGN TNVTELEERC RQLIGRYLRV ESHRKALVYQ KRYLKLTLEG YQASEQLALQ NLRGGAEQPP QRNIKKKFKT VALAIIAIQR IKYIGRIWHT GKRIVSKSVF TITQQRSPGL NLNVAPPQSP LPGPNSNLPT NNNNLMGRLS YAPLSPPMVN FSTVQPIMLP SDFTLQAPTT SLQTTIANNN SENTLPSLAR LDWPTMQKPK RAHARHH //