ID M4I2L9_MACOL Unreviewed; 191 AA. AC M4I2L9; DT 29-MAY-2013, integrated into UniProtKB/TrEMBL. DT 29-MAY-2013, sequence version 1. DT 19-JAN-2022, entry version 31. DE RecName: Full=Cytochrome c oxidase polypeptide I {ECO:0000256|ARBA:ARBA00020995}; DE AltName: Full=Cytochrome c oxidase subunit 1 {ECO:0000256|ARBA:ARBA00015947}; DE Flags: Fragment; GN Name=COI {ECO:0000313|EMBL:AFY12559.1}; OS Macrobrachium olfersii (Bristled river shrimp) (Palaemon olfersii). OG Mitochondrion {ECO:0000313|EMBL:AFY12559.1}. OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea; OC Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Caridea; OC Palaemonoidea; Palaemonidae; Macrobrachium. OX NCBI_TaxID=249258 {ECO:0000313|EMBL:AFY12559.1}; RN [1] {ECO:0000313|EMBL:AFY12559.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=23382941; DOI=10.1371/journal.pone.0054698; RA Rossi N., Mantelatto F.L.; RT "Molecular Analysis of the Freshwater Prawn Macrobrachium olfersii RT (Decapoda, Palaemonidae) Supports the Existence of a Single Species RT throughout Its Distribution."; RL PLoS ONE 8:E54698-E54698(2013). CC -!- CATALYTIC ACTIVITY: CC Reaction=4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)- CC [cytochrome c] + 4 H(+)(out) + 2 H2O; Xref=Rhea:RHEA:11436, CC Rhea:RHEA-COMP:10350, Rhea:RHEA-COMP:14399, ChEBI:CHEBI:15377, CC ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:29033, CC ChEBI:CHEBI:29034; EC=7.1.1.9; CC Evidence={ECO:0000256|ARBA:ARBA00024637}; CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:11437; CC Evidence={ECO:0000256|ARBA:ARBA00024637}; CC -!- PATHWAY: Energy metabolism; oxidative phosphorylation. CC {ECO:0000256|ARBA:ARBA00004673}. CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family. CC {ECO:0000256|ARBA:ARBA00009578}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JQ805936; AFY12559.1; -; Genomic_DNA. DR UniPathway; UPA00705; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC. DR GO; GO:0020037; F:heme binding; IEA:InterPro. DR GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway. DR Gene3D; 1.20.210.10; -; 1. DR InterPro; IPR023616; Cyt_c_oxase-like_su1_dom. DR InterPro; IPR036927; Cyt_c_oxase-like_su1_sf. DR InterPro; IPR000883; Cyt_C_Oxase_1. DR PANTHER; PTHR10422; PTHR10422; 1. DR Pfam; PF00115; COX1; 1. DR SUPFAM; SSF81442; SSF81442; 1. DR PROSITE; PS50855; COX1; 1. PE 3: Inferred from homology; KW Membrane {ECO:0000256|SAM:Phobius}; KW Mitochondrion {ECO:0000313|EMBL:AFY12559.1}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 6..23 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 35..55 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 67..90 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 102..123 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 143..161 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 173..190 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 1..191 FT /note="COX1" FT /evidence="ECO:0000259|PROSITE:PS50855" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:AFY12559.1" FT NON_TER 191 FT /evidence="ECO:0000313|EMBL:AFY12559.1" SQ SEQUENCE 191 AA; 21235 MW; 10A1A031869D197A CRC64; FFGHPEVYIS ILPAFGMISH IVSQESGKKE SFGTLGMVYA MMAIGVLGFV VWAHHMFTVG MDVDTRAYFT SATMIIAVPT GIKIFSWLAT LHGTQFTYSP SLIWALGFIF LFTMGGLTGV VLANSSIDII LHDTYYVVAH FHYFLSMGAV FGIFAGIAHW FPLFTGLSLH PKWLKIHFTT MFIGVNLTFF P //