ID M1X0B4_9NOST Unreviewed; 296 AA. AC M1X0B4; DT 01-MAY-2013, integrated into UniProtKB/TrEMBL. DT 01-MAY-2013, sequence version 1. DT 03-AUG-2022, entry version 31. DE RecName: Full=Carbonic anhydrase {ECO:0000256|ARBA:ARBA00014628, ECO:0000256|RuleBase:RU367011}; DE EC=4.2.1.1 {ECO:0000256|ARBA:ARBA00012925, ECO:0000256|RuleBase:RU367011}; GN ORFNames=RINTHH_12680 {ECO:0000313|EMBL:CCH67423.1}; OS Richelia intracellularis HH01. OC Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Richelia. OX NCBI_TaxID=1165094 {ECO:0000313|EMBL:CCH67423.1, ECO:0000313|Proteomes:UP000053051}; RN [1] {ECO:0000313|EMBL:CCH67423.1, ECO:0000313|Proteomes:UP000053051} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=HH01 {ECO:0000313|EMBL:CCH67423.1, RC ECO:0000313|Proteomes:UP000053051}; RA Hilton J.; RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Proteomes:UP000053051} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=HH01 {ECO:0000313|Proteomes:UP000053051}; RA Hilton J.A., Foster R.A., Tripp H.J., Carter B.J., Zehr J.P., RA Villareal T.A.; RT "Diatom-associated endosymboitic cyanobacterium lacks core nitrogen RT metabolism enzymes."; RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Reversible hydration of carbon dioxide. CC {ECO:0000256|RuleBase:RU367011}. CC -!- CATALYTIC ACTIVITY: CC Reaction=H(+) + hydrogencarbonate = CO2 + H2O; Xref=Rhea:RHEA:10748, CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, CC ChEBI:CHEBI:17544; EC=4.2.1.1; CC Evidence={ECO:0000256|ARBA:ARBA00000943, CC ECO:0000256|RuleBase:RU367011}; CC -!- COFACTOR: CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; CC Evidence={ECO:0000256|ARBA:ARBA00001947, CC ECO:0000256|RuleBase:RU367011}; CC -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family. CC {ECO:0000256|RuleBase:RU367011}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:CCH67423.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CAIY01000044; CCH67423.1; -; Genomic_DNA. DR STRING; 1165094.RINTHH_12680; -. DR EnsemblBacteria; CCH67423; CCH67423; RINTHH_12680. DR OrthoDB; 1572675at2; -. DR Proteomes; UP000053051; Unassembled WGS sequence. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0004089; F:carbonate dehydratase activity; IEA:UniProtKB-UniRule. DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule. DR CDD; cd03124; alpha_CA_prokaryotic_like; 1. DR Gene3D; 3.10.200.10; -; 1. DR InterPro; IPR041891; Alpha_CA_prokaryot-like. DR InterPro; IPR001148; CA_dom. DR InterPro; IPR036398; CA_dom_sf. DR InterPro; IPR023561; Carbonic_anhydrase_a-class. DR InterPro; IPR018338; Carbonic_anhydrase_a-class_CS. DR PANTHER; PTHR18952; PTHR18952; 1. DR Pfam; PF00194; Carb_anhydrase; 1. DR SMART; SM01057; Carb_anhydrase; 1. DR SUPFAM; SSF51069; SSF51069; 1. DR PROSITE; PS00162; ALPHA_CA_1; 1. DR PROSITE; PS51144; ALPHA_CA_2; 1. PE 3: Inferred from homology; KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU367011}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, KW ECO:0000256|RuleBase:RU367011}; KW Reference proteome {ECO:0000313|Proteomes:UP000053051}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}; KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU367011}. FT TRANSMEM 36..56 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 69..292 FT /note="Alpha-carbonic anhydrase" FT /evidence="ECO:0000259|PROSITE:PS51144" SQ SEQUENCE 296 AA; 33917 MW; B3ED19FAEF033607 CRC64; MQEVISDRIF GGFTTILVLI YKTHGFVSKT MNRRQLLRYF CVVTPTIAAT AATYSLQSRL LAAHNGSKVL WDYFGKKGAK NWGKLSPQFL TCRLGQSQSP INLTSAISAS IPNLQFNYNP STLRIFNNGH TIGVNYDNGS MLTLNGETYE LIQFHFHHPS EHTVDNKSYS MELHLIHKSK RGFIAVVGVF LKQGNYNQLL ESLWQMMPYQ ESKEVRFPYI TINAQDLIPQ SERVYMYYGS LTTPPCSENI YWIVFQEPLE ISTDQIQQFA GIFPMNARPV QELNSRFLLQ SSSHQY //