ID M1Q7B2_EPICO Unreviewed; 352 AA. AC M1Q7B2; DT 01-MAY-2013, integrated into UniProtKB/TrEMBL. DT 01-MAY-2013, sequence version 1. DT 10-FEB-2021, entry version 26. DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500}; OS Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Eupercaria; Perciformes; Serranoidei; Serranidae; Epinephelinae; OC Epinephelini; Epinephelus. OX NCBI_TaxID=94232 {ECO:0000313|EMBL:AGF91873.1}; RN [1] {ECO:0000313|EMBL:AGF91873.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=25598477; DOI=10.1016/j.cbpb.2015.01.002; RA Chen H., Li S., Xiao L., Zhang Y., Li G., Liu X., Lin H.; RT "Wnt4 in protogynous hermaphroditic orange-spotted grouper (Epinephelus RT coioides): identification and expression."; RL Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 183:67-74(2015). CC -!- FUNCTION: Ligand for members of the frizzled family of seven CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}. CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}. CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683, CC ECO:0000256|RuleBase:RU003500}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KC206549; AGF91873.1; -; mRNA. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW. DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro. DR GO; GO:0007275; P:multicellular organism development; IEA:UniProtKB-KW. DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW. DR Gene3D; 3.30.2460.20; -; 1. DR InterPro; IPR005817; Wnt. DR InterPro; IPR009142; Wnt4. DR InterPro; IPR043158; Wnt_C. DR InterPro; IPR018161; Wnt_CS. DR PANTHER; PTHR12027; PTHR12027; 1. DR Pfam; PF00110; wnt; 1. DR PRINTS; PR01844; WNT4PROTEIN. DR PRINTS; PR01349; WNTPROTEIN. DR SMART; SM00097; WNT1; 1. DR PROSITE; PS00246; WNT1; 1. PE 2: Evidence at transcript level; KW Developmental protein {ECO:0000256|ARBA:ARBA00022473, KW ECO:0000256|RuleBase:RU003500}; KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157}; KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530}; KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288}; KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}; KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687, KW ECO:0000256|RuleBase:RU003500}. FT SIGNAL 1..22 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 23..352 FT /note="Protein Wnt" FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5004016635" SQ SEQUENCE 352 AA; 39442 MW; 8F58BD9A6D994842 CRC64; MTEEYVLRCV LMLCCALLSA NASNWLHLAK LSSVGSIRDE ETCERLRGLI QRQVQICKRS VEVMDAVRRG AQLAIDECQF QFRNRRWNCS TLETMPVFGK VVTQGTREAA FVYAISAASV AFAVTRACSS GELEKCGCDH NVHGVSPEGF QWSGCSDNIA YGVAFSQSFV DVRERSKGQS SSRALMNLHN NEAGRKAILS HMRVECKCHG VSGSCEVKTC WKAMPPFRKV GNVIKEKFDG ATEVEQRKVG TTKVLVPRNS QFKPHTDEDL VYLDPSPDFC DYDPRTPGML GTVGRQCNRT SKAIDGCELM CCGRGFQTQE VEVVDRCSCK FHWCCYVKCK QCRKMVEMHT CR //