ID M1JB81_9TELE Unreviewed; 378 AA. AC M1JB81; DT 01-MAY-2013, integrated into UniProtKB/TrEMBL. DT 01-MAY-2013, sequence version 1. DT 11-DEC-2019, entry version 30. DE RecName: Full=Cytochrome b {ECO:0000256|RuleBase:RU362117}; GN Name=cytb {ECO:0000313|EMBL:AGE83194.1}; GN Synonyms=Cyt b {ECO:0000313|EMBL:BAV69468.1}; OS Amblyrhynchichthys truncatus. OG Mitochondrion {ECO:0000313|EMBL:AGE83194.1}. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Amblyrhynchichthys. OX NCBI_TaxID=643417 {ECO:0000313|EMBL:AGE83194.1}; RN [1] {ECO:0000313|EMBL:BAV69468.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=CBM ZF 11208 {ECO:0000313|EMBL:BAV69468.1}; RA Miya M.; RT "Whole mitochondrial genome sequences in Cypriniformes."; RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:AGE83194.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=CTOL01545 {ECO:0000313|EMBL:AGE83194.1}; RA Yang L., Hirt M.V., Sado T., Arunachalam M., Manickam R., Tang K.L., RA Simons A.M., Wu H.-H., Mayden R.L., Miya M.; RT "Phylogenetic placements of the barbin genera Discherodontus, Chagunius, RT and Hypselobarbus in the subfamily Cyprininae (Teleostei: Cypriniformes) RT and their relationships with other barbins."; RL Zootaxa 3586:26-40(2012). CC -!- FUNCTION: Component of the ubiquinol-cytochrome c reductase complex CC (complex III or cytochrome b-c1 complex) that is part of the CC mitochondrial respiratory chain. The b-c1 complex mediates electron CC transfer from ubiquinol to cytochrome c. Contributes to the generation CC of a proton gradient across the mitochondrial membrane that is then CC used for ATP synthesis. {ECO:0000256|RuleBase:RU362117}. CC -!- COFACTOR: CC Name=heme; Xref=ChEBI:CHEBI:30413; CC Evidence={ECO:0000256|PIRSR:PIRSR038885-2, CC ECO:0000256|RuleBase:RU362117}; CC Note=Binds 2 heme groups non-covalently. CC {ECO:0000256|PIRSR:PIRSR038885-2, ECO:0000256|RuleBase:RU362117}; CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane CC {ECO:0000256|RuleBase:RU362117}. CC -!- SIMILARITY: Belongs to the cytochrome b family. CC {ECO:0000256|RuleBase:RU362117}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JX066769; AGE83194.1; -; Genomic_DNA. DR EMBL; AP011179; BAV69468.1; -; Genomic_DNA. DR RefSeq; YP_009310916.1; NC_031519.1. DR GeneID; 29992107; -. DR CTD; 4519; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0045275; C:respiratory chain complex III; IEA:InterPro. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule. DR GO; GO:0008121; F:ubiquinol-cytochrome-c reductase activity; IEA:InterPro. DR GO; GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; IEA:InterPro. DR CDD; cd00290; cytochrome_b_C; 1. DR CDD; cd00284; Cytochrome_b_N; 1. DR Gene3D; 1.20.810.10; -; 1. DR InterPro; IPR005798; Cyt_b/b6_C. DR InterPro; IPR036150; Cyt_b/b6_C_sf. DR InterPro; IPR005797; Cyt_b/b6_N. DR InterPro; IPR027387; Cytb/b6-like_sf. DR InterPro; IPR030689; Cytochrome_b. DR InterPro; IPR016174; Di-haem_cyt_TM. DR Pfam; PF00032; Cytochrom_B_C; 1. DR Pfam; PF00033; Cytochrome_B; 1. DR PIRSF; PIRSF038885; COB; 1. DR SUPFAM; SSF81342; SSF81342; 1. DR SUPFAM; SSF81648; SSF81648; 1. DR PROSITE; PS51003; CYTB_CTER; 1. DR PROSITE; PS51002; CYTB_NTER; 1. PE 3: Inferred from homology; KW Electron transport {ECO:0000256|RuleBase:RU362117}; KW Heme {ECO:0000256|PIRSR:PIRSR038885-2, ECO:0000256|RuleBase:RU362117}; KW Iron {ECO:0000256|PIRSR:PIRSR038885-2, ECO:0000256|RuleBase:RU362117}; KW Membrane {ECO:0000256|RuleBase:RU362117}; KW Metal-binding {ECO:0000256|PIRSR:PIRSR038885-2, KW ECO:0000256|RuleBase:RU362117}; KW Mitochondrion {ECO:0000256|RuleBase:RU362117, ECO:0000313|EMBL:AGE83194.1}; KW Respiratory chain {ECO:0000256|RuleBase:RU362117}; KW Transmembrane {ECO:0000256|RuleBase:RU362117}; KW Transmembrane helix {ECO:0000256|RuleBase:RU362117}; KW Transport {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 29..52 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362117" FT TRANSMEM 87..107 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362117" FT TRANSMEM 113..133 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362117" FT TRANSMEM 145..166 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362117" FT TRANSMEM 178..200 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362117" FT TRANSMEM 229..250 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362117" FT TRANSMEM 288..308 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362117" FT TRANSMEM 320..341 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362117" FT TRANSMEM 347..372 FT /note="Helical" FT /evidence="ECO:0000256|RuleBase:RU362117" FT DOMAIN 1..209 FT /note="CYTB_NTER" FT /evidence="ECO:0000259|PROSITE:PS51002" FT DOMAIN 210..378 FT /note="CYTB_CTER" FT /evidence="ECO:0000259|PROSITE:PS51003" FT METAL 83 FT /note="Iron 1 (heme b562 axial ligand)" FT /evidence="ECO:0000256|PIRSR:PIRSR038885-2" FT METAL 97 FT /note="Iron 2 (heme b566 axial ligand)" FT /evidence="ECO:0000256|PIRSR:PIRSR038885-2" FT METAL 182 FT /note="Iron 1 (heme b562 axial ligand)" FT /evidence="ECO:0000256|PIRSR:PIRSR038885-2" FT METAL 196 FT /note="Iron 2 (heme b566 axial ligand)" FT /evidence="ECO:0000256|PIRSR:PIRSR038885-2" FT BINDING 201 FT /note="Ubiquinone" FT /evidence="ECO:0000256|PIRSR:PIRSR038885-1" SQ SEQUENCE 378 AA; 42660 MW; D7A7C04B90B78C84 CRC64; MASLRKTHPL MKIANDALVD LPAPSNISVW WNFGSLLGLC LITQILTGLF LAMHYTSDIS TAFSSVVHIC RDVNYGWLIR NIHANGASFF FICIYMHIAR GLYYGSYLYK ETWNIGVVLL LLVMMTAFVG YVLPWGQMSF WGATVITNLL SAVPYVGDML VQWIWGGFSV DNATLTRFFA FHFLLPFIIA AMTILHLLFL HETGSNNPIG LNSNADKIPF HPYFTYKDLL GFVIMLLALM MLALFSPNLL GDPENFTPAN PLVTPPHIKP EWYFLFAYAI LRSIPNKLGG VLALLFSILV LMVVPFLHTS KQRGMAFRPI SQFLFWTLVA DMIILTWIGG MPVEHPFIII GQIASVLYFM LFLILMPLAG WLENKAME //