ID M1D197_SOLTU Unreviewed; 222 AA. AC M1D197; DT 03-APR-2013, integrated into UniProtKB/TrEMBL. DT 03-APR-2013, sequence version 1. DT 12-AUG-2020, entry version 25. DE RecName: Full=Alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase {ECO:0000256|ARBA:ARBA00012671}; DE EC=2.4.1.155 {ECO:0000256|ARBA:ARBA00012671}; OS Solanum tuberosum (Potato). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum. OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400079116}; RN [1] {ECO:0000313|EnsemblPlants:PGSC0003DMT400079116} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. DM1-3 516 R44 RC {ECO:0000313|EnsemblPlants:PGSC0003DMT400079116}; RX PubMed=21743474; DOI=10.1038/nature10158; RG The Potato Genome Sequencing Consortium; RT "Genome sequence and analysis of the tuber crop potato."; RL Nature 475:189-195(2011). RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400079116} RP IDENTIFICATION. RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400079116}; RG EnsemblPlants; RL Submitted (JUN-2015) to UniProtKB. CC -!- CATALYTIC ACTIVITY: CC Reaction=N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man- CC (1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)- CC beta-D-GlcNAcl-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N- CC acetyl-alpha-D-glucosamine = H(+) + N(4)-{beta-D-GlcNAc-(1->2)-[beta- CC D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D- CC GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl- CC (1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP; CC Xref=Rhea:RHEA:16921, Rhea:RHEA-COMP:14374, Rhea:RHEA-COMP:14377, CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57705, ChEBI:CHEBI:58223, CC ChEBI:CHEBI:139507, ChEBI:CHEBI:139510; EC=2.4.1.155; CC Evidence={ECO:0000256|ARBA:ARBA00000454}; CC -!- PATHWAY: Protein modification; protein glycosylation. CC {ECO:0000256|ARBA:ARBA00004922}. CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane CC {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein CC {ECO:0000256|ARBA:ARBA00004323}. Membrane CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein CC {ECO:0000256|ARBA:ARBA00004606}. Secreted CC {ECO:0000256|ARBA:ARBA00004613}. CC -!- SIMILARITY: Belongs to the UPF0454 family. CC {ECO:0000256|ARBA:ARBA00010806}. CC -!- SIMILARITY: Belongs to the glycosyltransferase 18 family. CC {ECO:0000256|ARBA:ARBA00007477}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR STRING; 4113.PGSC0003DMT400079116; -. DR EnsemblPlants; PGSC0003DMT400079116; PGSC0003DMT400079116; PGSC0003DMG400030791. DR Gramene; PGSC0003DMT400079116; PGSC0003DMT400079116; PGSC0003DMG400030791. DR eggNOG; KOG3136; Eukaryota. DR HOGENOM; CLU_082320_0_0_1; -. DR InParanoid; M1D197; -. DR OMA; LQCCDSY; -. DR UniPathway; UPA00378; -. DR Proteomes; UP000011115; Unassembled WGS sequence. DR GO; GO:0030144; F:alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity; IEA:InterPro. DR GO; GO:0006487; P:protein N-linked glycosylation; IEA:InterPro. DR InterPro; IPR026116; GlyclTrfase_18. DR InterPro; IPR019352; UPF0454. DR PANTHER; PTHR13481; PTHR13481; 1. DR Pfam; PF10218; DUF2054; 1. DR Pfam; PF15024; Glyco_transf_18; 1. PE 3: Inferred from homology; KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180}; KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676}; KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034}; KW Membrane {ECO:0000256|ARBA:ARBA00023136}; KW Reference proteome {ECO:0000313|Proteomes:UP000011115}; KW Secreted {ECO:0000256|ARBA:ARBA00022525}; KW Signal {ECO:0000256|ARBA:ARBA00022729}; KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}. SQ SEQUENCE 222 AA; 23739 MW; 1BADFEEEA9CD5561 CRC64; MGQVCDALSI DPHSRCCRGK SERFSCNGCN LVLQCCNSYE FCVSCCLNPS RTQKDLAVIV KISKPITAGM YSSIFDFCTG RCRHNSESVV HENAYLSEFH HCFSIPSNSS SGGASGVQTE VRLAGINVVI GKQGESCDSV CKSSGQSCVP NKFVLLNQCE TMHKYLSCKG GCLASVGADQ PAEVVDDAPR DLNPGACLYT SQASVLSCDG SHQHTKRLCP CA //