ID M0RC30_RAT Unreviewed; 310 AA. AC M0RC30; DT 03-APR-2013, integrated into UniProtKB/TrEMBL. DT 03-APR-2013, sequence version 1. DT 22-NOV-2017, entry version 41. DE RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047}; GN Name=Olr576 {ECO:0000313|Ensembl:ENSRNOP00000067136, GN ECO:0000313|RGD:1333225}; OS Rattus norvegicus (Rat). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Rattus. OX NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000067136, ECO:0000313|Proteomes:UP000002494}; RN [1] {ECO:0000313|Ensembl:ENSRNOP00000067136, ECO:0000313|Proteomes:UP000002494} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000067136, RC ECO:0000313|Proteomes:UP000002494}; RX PubMed=15057822; DOI=10.1038/nature02426; RG Rat Genome Sequencing Project Consortium; RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., RA Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., RA Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., RA Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., RA Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., RA Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., RA Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., RA Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., RA Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., RA D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., RA Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., RA Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., RA Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., RA Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., RA Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., RA Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., RA Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., RA Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., RA Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., RA Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., RA Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., RA Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., RA Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., RA Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., RA Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., RA Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., RA Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., RA Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., RA Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., RA Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., RA Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., RA Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., RA Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., RA Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., RA Collins F.S.; RT "Genome sequence of the Brown Norway rat yields insights into RT mammalian evolution."; RL Nature 428:493-521(2004). RN [2] {ECO:0000313|Ensembl:ENSRNOP00000067136} RP IDENTIFICATION. RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000067136}; RG Ensembl; RL Submitted (FEB-2013) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Cell membrane CC {ECO:0000256|RuleBase:RU363047, ECO:0000256|SAAS:SAAS00857205}; CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047, CC ECO:0000256|SAAS:SAAS00857205}. CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family. CC {ECO:0000256|RuleBase:RU363047, ECO:0000256|SAAS:SAAS00857212}. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSRNOP00000067136}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AABR07052795; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR ProteinModelPortal; M0RC30; -. DR STRING; 10116.ENSRNOP00000067136; -. DR PaxDb; M0RC30; -. DR Ensembl; ENSRNOT00000071529; ENSRNOP00000067136; ENSRNOG00000047926. DR RGD; 1333225; Olr576. DR eggNOG; ENOG410IGY6; Eukaryota. DR eggNOG; ENOG4111BJU; LUCA. DR GeneTree; ENSGT00900000140819; -. DR InParanoid; M0RC30; -. DR OMA; DYQLHTP; -. DR OrthoDB; EOG091G0AZH; -. DR PhylomeDB; M0RC30; -. DR Reactome; R-RNO-381753; Olfactory Signaling Pathway. DR Proteomes; UP000002494; Chromosome 3. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW. DR GO; GO:0005549; F:odorant binding; IBA:GO_Central. DR GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central. DR GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IBA:GO_Central. DR InterPro; IPR000276; GPCR_Rhodpsn. DR InterPro; IPR017452; GPCR_Rhodpsn_7TM. DR InterPro; IPR000725; Olfact_rcpt. DR Pfam; PF13853; 7tm_4; 1. DR PRINTS; PR00237; GPCRRHODOPSN. DR PRINTS; PR00245; OLFACTORYR. DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1. DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1. PE 3: Inferred from homology; KW Cell membrane {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00857207}; KW Complete proteome {ECO:0000313|Proteomes:UP000002494}; KW G-protein coupled receptor {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00857203}; KW Membrane {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00857208}; KW Olfaction {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00857209}; KW Receptor {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00857193}; KW Reference proteome {ECO:0000313|Proteomes:UP000002494}; KW Sensory transduction {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00857210}; KW Transducer {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00857213}; KW Transmembrane {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00857211}; KW Transmembrane helix {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00857194}. FT TRANSMEM 25 48 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 60 78 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 98 120 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 140 158 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 197 223 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 235 260 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 275 292 Helical. {ECO:0000256|RuleBase:RU363047}. FT DOMAIN 41 290 G_PROTEIN_RECEP_F1_2. FT {ECO:0000259|PROSITE:PS50262}. SQ SEQUENCE 310 AA; 34726 MW; 3A966CE3533EF57D CRC64; MDKKNCSSVG EFIFLGITNN PDMKVALFTT LLLVYLINLL ANLGMIILIR VDTQLQTPMY FFLSHLSFCD LCYSTAIGPK MLVDLLAEEK SIPIVGCALQ FFTFCVFADS ECLLLAVMAY DRYQAINNPL LYTVNMSSRL CSLLMSGVYL VGTADALIHT TLAFRLCFCR SNEINHFFCD VPPLLLISCS DTEANELAIF TIFGFIELST ISGVLVSYSY IILSVLKICS AEGRFKAFST CASHLTAVAV FQGTMLFMYF RPSSSYSLDQ DKMTSLFYTL VIPMLNPLIY SLRNKDVKEA LAKLNKKSYY //