ID L7QGV3_9INFA Unreviewed; 498 AA. AC L7QGV3; DT 03-APR-2013, integrated into UniProtKB/TrEMBL. DT 03-APR-2013, sequence version 1. DT 27-NOV-2024, entry version 45. DE RecName: Full=Nucleoprotein {ECO:0000256|RuleBase:RU361251}; DE Flags: Fragment; GN Name=NP {ECO:0000256|RuleBase:RU361251, ECO:0000313|EMBL:AGA19351.1}; OS Influenza A virus (A/elephant seal/California/2/2010(H1N1)). OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina; OC Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus; OC Alphainfluenzavirus influenzae; Influenza A virus. OX NCBI_TaxID=1263915 {ECO:0000313|EMBL:AGA19351.1}; RN [1] {ECO:0000313|EMBL:AGA19351.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=A/elephant seal/California/2/2010 RC {ECO:0000313|EMBL:AGA19351.1}; RX PubMed=23690933; RA Goldstein T., Mena I., Anthony S.J., Medina R., Robinson P.W., Greig D.J., RA Costa D.P., Lipkin W.I., Garcia-Sastre A., Boyce W.M.; RT "Pandemic H1N1 Influenza Isolated from Free-Ranging Northern Elephant Seals RT in 2010 off the Central California Coast."; RL PLoS ONE 8:E62259-E62259(2013). CC -!- FUNCTION: Encapsidates the negative strand viral RNA, protecting it CC from nucleases. The encapsidated genomic RNA is termed the CC ribonucleoprotein (RNP) and serves as template for transcription and CC replication. {ECO:0000256|RuleBase:RU361251}. CC -!- SUBUNIT: Homomultimerizes to form the nucleocapsid. CC {ECO:0000256|RuleBase:RU361251}. CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000256|RuleBase:RU361251}. Host CC nucleus {ECO:0000256|RuleBase:RU361251}. CC -!- SIMILARITY: Belongs to the influenza viruses nucleoprotein family. CC {ECO:0000256|RuleBase:RU361251}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KC222503; AGA19351.1; -; Viral_cRNA. DR GO; GO:0019029; C:helical viral capsid; IEA:UniProtKB-KW. DR GO; GO:0043657; C:host cell; IEA:GOC. DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell. DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW. DR GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-UniRule. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW. DR GO; GO:0005198; F:structural molecule activity; IEA:UniProtKB-UniRule. DR GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-KW. DR HAMAP; MF_04070; INFV_NCAP; 1. DR InterPro; IPR002141; Flu_NP. DR Pfam; PF00506; Flu_NP; 1. DR SUPFAM; SSF161003; flu NP-like; 1. PE 3: Inferred from homology; KW Capsid protein {ECO:0000256|ARBA:ARBA00022561, KW ECO:0000256|RuleBase:RU361251}; KW Helical capsid protein {ECO:0000256|ARBA:ARBA00022497}; KW Host nucleus {ECO:0000256|ARBA:ARBA00022562, KW ECO:0000256|RuleBase:RU361251}; KW Host-virus interaction {ECO:0000256|ARBA:ARBA00022581}; KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274}; KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}; KW Viral nucleoprotein {ECO:0000256|ARBA:ARBA00023086, KW ECO:0000256|RuleBase:RU361251}; KW Viral penetration into host nucleus {ECO:0000256|ARBA:ARBA00022524}; KW Virion {ECO:0000256|ARBA:ARBA00022844, ECO:0000256|RuleBase:RU361251}; KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}. FT REGION 1..22 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 498 FT /evidence="ECO:0000313|EMBL:AGA19351.1" SQ SEQUENCE 498 AA; 56009 MW; 23476CB9A166A4D3 CRC64; MASQGTKRSY EQMETGGERQ DATEIRASVG RMIGGIGRFY IQMCTELKLS DYDGRLIQNS ITIERMVLSA FDERRNKYLE EHPSAGKDPK KTGGPIYRRI NGKWMRELIL YDKEEIRRVW RQANNGEDAT AGLTHIMIWH SNLNDATYQR TRALVRTGMD PRMCSLMQGS TLPRRSGAAG AAVKGVGTIA MELIRMIKRG INDRNFWRGE NGRRTRVAYE RMCNILKGKF QTAAQRAMMD QVRESRNPGN AEIEDLIFLT RSALILRGSV AHKSCLPACV YGLAVASGHD FEREGYSLVG IDPFKLLQNS QVVSLMRPNE NPAHKSQLVW MACHSAAFED LRVSSFIRGK KVIPRGKLST RGVQVASNEN VETMDSNTLE LRSRYWAIRT RSGGNTNQQK ASAGQISVQP TFSVQRNLPF ERATVMAAFS GNNEGRTSDM RTEVIRMMES AKPEDLSFQG RGVFELSDEK ATNPIVPSFD MSNEGSYFFG DNAEEYDS //