ID L7P6F3_9INFA Unreviewed; 498 AA. AC L7P6F3; DT 03-APR-2013, integrated into UniProtKB/TrEMBL. DT 03-APR-2013, sequence version 1. DT 28-FEB-2018, entry version 32. DE RecName: Full=Nucleoprotein {ECO:0000256|HAMAP-Rule:MF_04070}; DE AltName: Full=Nucleocapsid protein {ECO:0000256|HAMAP-Rule:MF_04070}; DE Short=Protein N {ECO:0000256|HAMAP-Rule:MF_04070}; GN Name=NP {ECO:0000256|HAMAP-Rule:MF_04070, GN ECO:0000313|EMBL:AFO83401.1}; OS Influenza A virus (A/duck/Guangxi/GXd-3/2009(H6N2)). OC Viruses; ssRNA viruses; ssRNA negative-strand viruses; OC Orthomyxoviridae; Influenzavirus A. OX NCBI_TaxID=1208725 {ECO:0000313|EMBL:AFO83401.1, ECO:0000313|Proteomes:UP000117558}; RN [1] {ECO:0000313|EMBL:AFO83401.1, ECO:0000313|Proteomes:UP000117558} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=A/duck/Guangxi/GXd-3/2009 {ECO:0000313|EMBL:AFO83401.1}; RA Xie Z., Zhou C., Peng Y., Liu J., Pang Y., Deng X., Xie Z., Xie L., RA Fan Q.; RT "Genetic Characterization of H6 Subtype Avian Influenza Virus."; RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Host nucleus CC {ECO:0000256|SAAS:SAAS00966152}. CC -!- PTM: Late in virus-infected cells, may be cleaved from a 56-kDa CC protein to a 53-kDa protein by a cellular caspase. This cleavage CC might be a marker for the onset of apoptosis in infected cells or CC have a specific function in virus host interaction. CC {ECO:0000256|HAMAP-Rule:MF_04070}. CC -!- SIMILARITY: Belongs to the influenza viruses nucleoprotein family. CC {ECO:0000256|HAMAP-Rule:MF_04070, ECO:0000256|SAAS:SAAS00966161}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JX297580; AFO83401.1; -; Viral_cRNA. DR Proteomes; UP000117558; Genome. DR GO; GO:0019029; C:helical viral capsid; IEA:UniProtKB-UniRule. DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-UniRule. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0005198; F:structural molecule activity; IEA:UniProtKB-UniRule. DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW. DR GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-UniRule. DR HAMAP; MF_04070; INFV_NCAP; 1. DR InterPro; IPR002141; Flu_NP. DR Pfam; PF00506; Flu_NP; 1. PE 3: Inferred from homology; KW Capsid protein {ECO:0000256|HAMAP-Rule:MF_04070, KW ECO:0000256|SAAS:SAAS00966151}; KW Complete proteome {ECO:0000313|Proteomes:UP000117558}; KW Helical capsid protein {ECO:0000256|HAMAP-Rule:MF_04070, KW ECO:0000256|SAAS:SAAS00966174}; KW Host nucleus {ECO:0000256|HAMAP-Rule:MF_04070, KW ECO:0000256|SAAS:SAAS00966147}; KW Host-virus interaction {ECO:0000256|HAMAP-Rule:MF_04070, KW ECO:0000256|SAAS:SAAS00966156}; KW Ribonucleoprotein {ECO:0000256|HAMAP-Rule:MF_04070, KW ECO:0000256|SAAS:SAAS00966134}; KW RNA-binding {ECO:0000256|HAMAP-Rule:MF_04070, KW ECO:0000256|SAAS:SAAS00966163}; KW Viral nucleoprotein {ECO:0000256|HAMAP-Rule:MF_04070, KW ECO:0000313|EMBL:AFO83401.1}; KW Viral penetration into host nucleus {ECO:0000256|HAMAP-Rule:MF_04070, KW ECO:0000256|SAAS:SAAS00966166}; KW Virion {ECO:0000256|HAMAP-Rule:MF_04070, KW ECO:0000256|SAAS:SAAS00966164}; KW Virus entry into host cell {ECO:0000256|HAMAP-Rule:MF_04070, KW ECO:0000256|SAAS:SAAS00966165}. FT MOTIF 1 18 Unconventional nuclear localization FT signal. {ECO:0000256|HAMAP-Rule: FT MF_04070}. FT MOTIF 198 216 Bipartite nuclear localization signal. FT {ECO:0000256|HAMAP-Rule:MF_04070}. SQ SEQUENCE 498 AA; 56238 MW; FC2C78F8DC4A8FB8 CRC64; MASQGTKRSY EQMETGGERQ NATEIRASVG RMVGGIGRFY IQMCTELKLS DYEGRLIQNS ITIERMVLSA FDERRNKYLE EHPSAGKDPK KTGGPVYRRR DGKWMRELIL YDKEEIRRIW RQANNGEEAT AGLTHLMIWH SNLNDATYQR TRALVRTGMD PRMCSLMQGS TLPRRSGAAG AAVKGVGTMV MELIRMIKRG INDRNFWRGE NGRRTRIAYE RMCNILKGKF QTAAQRAMMD QVRESRNPGN AEIEDLIFLA RSALILRGSV AHKSCLPACV YGLAVASGYD FEREGYSLVG IDPFRLLQNS QVFSLIRPNE NPAHKSQLVW MACHSAAFED LRVSSFIRGT RVVPRGQLST RGVQIASNEN VETMDSSTLE LRSRYWAIRT RSGGNTNQQR ASAGQISVQP TFSVQRNLPF ERATIMAAFT GNTEGRTSDM RTEIIRMMES AKPEDVSFQG RGVFELSDEK ATNPIVPSFD MSKEGSYFFG DNAEEYDN //