ID L7NTC5_CRONI Unreviewed; 261 AA. AC L7NTC5; DT 03-APR-2013, integrated into UniProtKB/TrEMBL. DT 03-APR-2013, sequence version 1. DT 29-MAY-2024, entry version 39. DE SubName: Full=Hox D11 {ECO:0000313|EMBL:AEZ53147.1}; DE Flags: Fragment; OS Crocodylus niloticus (Nile crocodile) (African crocodile). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Archelosauria; Archosauria; Crocodylia; Longirostres; Crocodylidae; OC Crocodylus. OX NCBI_TaxID=8501 {ECO:0000313|EMBL:AEZ53147.1}; RN [1] {ECO:0000313|EMBL:AEZ53147.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=CN_D11 {ECO:0000313|EMBL:AEZ53147.1}; RA Fowler D.A., de Bakker M.A.G., Sire J.Y., Richardson M.K.; RT "Adding to the limb puzzle: Hox expression in Archosaurs."; RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Sequence-specific transcription factor which is part of a CC developmental regulatory system that provides cells with specific CC positional identities on the anterior-posterior axis. CC {ECO:0000256|ARBA:ARBA00003263}. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123, CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}. CC -!- SIMILARITY: Belongs to the Abd-B homeobox family. CC {ECO:0000256|ARBA:ARBA00006317}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JF317537; AEZ53147.1; -; mRNA. DR AlphaFoldDB; L7NTC5; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter. DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter. DR CDD; cd00086; homeodomain; 1. DR Gene3D; 1.10.10.60; Homeodomain-like; 1. DR InterPro; IPR021918; DUF3528. DR InterPro; IPR009057; Homeobox-like_sf. DR InterPro; IPR001356; Homeobox_dom. DR InterPro; IPR020479; Homeobox_metazoa. DR PANTHER; PTHR46092; HOMEOBOX PROTEIN HOX-A11-RELATED; 1. DR PANTHER; PTHR46092:SF2; HOMEOBOX PROTEIN HOX-D11; 1. DR Pfam; PF12045; DUF3528; 1. DR Pfam; PF00046; Homeodomain; 1. DR PRINTS; PR00024; HOMEOBOX. DR SMART; SM00389; HOX; 1. DR SUPFAM; SSF46689; Homeodomain-like; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. PE 2: Evidence at transcript level; KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108, KW ECO:0000256|RuleBase:RU000682}; KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE- KW ProRule:PRU00108}; KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, KW ECO:0000256|RuleBase:RU000682}. FT DOMAIN 206..261 FT /note="Homeobox" FT /evidence="ECO:0000259|PROSITE:PS50071" FT REGION 134..211 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 163..207 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 261 FT /evidence="ECO:0000313|EMBL:AEZ53147.1" SQ SEQUENCE 261 AA; 29839 MW; 74872BE2C143C1E8 CRC64; MTEFEDCSHS AANMYLPGCA YYVSPSDFST KPSFLSQSSS CQMTFPYSSN LPHVQPVREM AFREYGLERS KWQYRGSYAP YYSAEEVMHR DFLQPANRRT EMLFKTDPVC NHHGPSGAAS NFYSSVGRNG ILPQGFDQFY EPAPGPPYQP QSEPEGDGDK SDLKAQSSTC SKTPSSQEKK VTPANSAESP SGEAVAEKSN SSAVPQRSRK KRCPYTKYQI RELEREFFFN VYINKEKRLQ LSRMLNLTDR QVKIWFQNRR M //