ID L5L6R0_PTEAL Unreviewed; 476 AA. AC L5L6R0; DT 06-MAR-2013, integrated into UniProtKB/TrEMBL. DT 06-MAR-2013, sequence version 1. DT 12-AUG-2020, entry version 19. DE RecName: Full=Inhibitor of kappa B-like protein {ECO:0000256|ARBA:ARBA00016262}; DE AltName: Full=NF-kappa-B inhibitor-like protein 1 {ECO:0000256|ARBA:ARBA00014259}; DE AltName: Full=Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 {ECO:0000256|ARBA:ARBA00013990}; GN ORFNames=PAL_GLEAN10001100 {ECO:0000313|EMBL:ELK18936.1}; OS Pteropus alecto (Black flying fox). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae; OC Pteropodinae; Pteropus. OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK18936.1, ECO:0000313|Proteomes:UP000010552}; RN [1] {ECO:0000313|Proteomes:UP000010552} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=23258410; DOI=10.1126/science.1230835; RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X., RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P., RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X., RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F., RA Wang J.; RT "Comparative analysis of bat genomes provides insight into the evolution of RT flight and immunity."; RL Science 339:456-460(2013). CC -!- SUBUNIT: Interacts with CACTIN (via N-terminal domain); the interaction CC occurs in a proinflammatory-independent manner. CC {ECO:0000256|ARBA:ARBA00011310}. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KB030277; ELK18936.1; -; Genomic_DNA. DR STRING; 9402.XP_006904742.1; -. DR eggNOG; ENOG502QTMZ; Eukaryota. DR InParanoid; L5L6R0; -. DR Proteomes; UP000010552; Unassembled WGS sequence. DR GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IEA:InterPro. DR Gene3D; 1.25.40.20; -; 1. DR InterPro; IPR020683; Ankyrin_rpt-contain_dom. DR InterPro; IPR036770; Ankyrin_rpt-contain_sf. DR InterPro; IPR038753; NFKBIL1. DR PANTHER; PTHR15263; PTHR15263; 1. DR SUPFAM; SSF48403; SSF48403; 1. DR PROSITE; PS50297; ANK_REP_REGION; 1. PE 4: Predicted; KW Reference proteome {ECO:0000313|Proteomes:UP000010552}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}. FT DOMAIN 57..126 FT /note="ANK_REP_REGION" FT /evidence="ECO:0000259|PROSITE:PS50297" FT REGION 1..22 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 119..151 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 195..231 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 247..284 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 196..212 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 247..264 FT /note="Polyampholyte" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 476 AA; 53892 MW; C0399CCCF358344B CRC64; MMGMQVNTKS SMASTSRRQR REHRFRRYLS SGRLVRAQAL FQRHPGLDVD AGQPPTLHRA CARHDAPALC LLLRLGADPA HQDRHGDTAL HAAARQGPDA YTDFFLPLLS RCPSAMGIKN KDGETPGQIL GWGPPRDSTE EEEEDEAFRE REWRQKLQGE LEDEWQEVIG RFEDDASLEA QEPESFSAWS DRLAWEHAQK QQQQQQQQRE AKGTCRPPRA EGSSHSWWQQ EEQRIFRERA RAKAEDLCES RARREQDAHR DQGLKPARAG SGVEHPSGGG RGSLWRFGDV PWPCPGGGDP EAMAAALMAR GPPLEEQGAL RRYLRIQQVR WHPDRFLQRF RSQIETWELG RVMGAVTALS QALNRHAEAF FERVKNCRDC SLRARAVERV WSKMGMMRKR PMLHGRGYGV GAKLVISGGG EDTATTTVLQ LCHFLIRPGS TSHSRCLCLF PLLWFSPPMT SPFPPCLPKP TAPTHL //