ID L0ECE0_THECK Unreviewed; 419 AA. AC L0ECE0; DT 06-MAR-2013, integrated into UniProtKB/TrEMBL. DT 06-MAR-2013, sequence version 1. DT 24-JAN-2024, entry version 46. DE SubName: Full=Sugar phosphate permease {ECO:0000313|EMBL:AGA57341.1}; GN OrderedLocusNames=Theco_1170 {ECO:0000313|EMBL:AGA57341.1}; OS Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4). OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Thermobacillus. OX NCBI_TaxID=717605 {ECO:0000313|EMBL:AGA57341.1, ECO:0000313|Proteomes:UP000010795}; RN [1] {ECO:0000313|Proteomes:UP000010795} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DSM 18247 / JCM 13945 / KWC4 RC {ECO:0000313|Proteomes:UP000010795}; RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., RA Peters L., Ovchinnikova G., Teshima H., Detter J.C., Han C., Tapia R., RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Anderson I., RA Woyke T.; RT "Complete sequence of chromosome of Thermobacillus composti KWC4."; RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004141}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP003255; AGA57341.1; -; Genomic_DNA. DR RefSeq; WP_015254098.1; NC_019897.1. DR AlphaFoldDB; L0ECE0; -. DR STRING; 717605.Theco_1170; -. DR KEGG; tco:Theco_1170; -. DR eggNOG; COG2271; Bacteria. DR HOGENOM; CLU_001265_59_9_9; -. DR OMA; SMRICAF; -. DR Proteomes; UP000010795; Chromosome. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro. DR CDD; cd17355; MFS_YcxA_like; 1. DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2. DR InterPro; IPR011701; MFS. DR InterPro; IPR020846; MFS_dom. DR InterPro; IPR036259; MFS_trans_sf. DR PANTHER; PTHR11360:SF290; BLL4329 PROTEIN; 1. DR PANTHER; PTHR11360; MONOCARBOXYLATE TRANSPORTER; 1. DR Pfam; PF07690; MFS_1; 1. DR SUPFAM; SSF103473; MFS general substrate transporter; 1. DR PROSITE; PS50850; MFS; 1. PE 4: Predicted; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000010795}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}. FT TRANSMEM 12..29 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 49..69 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 81..103 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 109..132 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 139..164 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 170..190 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 234..257 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 269..290 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 357..379 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 391..411 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 14..415 FT /note="Major facilitator superfamily (MFS) profile" FT /evidence="ECO:0000259|PROSITE:PS50850" SQ SEQUENCE 419 AA; 45162 MW; 8DCF60717462F764 CRC64; MHAAGKLKWH YGWVVVAITF ATLVVSAGVR SMPGILMLPL ADEFDWSRSA ISSVMSVGIF LYGMMGPFAA SLLQKYGIRR VTVISLSLLA ASLVLTPLMQ TLWQFQLLWG LLSGLATGMM ANVLGVTVAG NWFTERRGLF VGILTASAAS GQLIFLPLLA KIISEAGWRY AIYAAAAAVL LVLIIVAVGV RNHPYDIGAA PYGSDQVSRP EEFKGRIFLT PLLVLKDASR NSTFWLLSGT FFFCGVSTNG LISTHLIPAC GDFGITEVVA AGLLAFMGIF DLTGTTLSGW LSDRFDSRKL LFWYYGLRGL SLIFLPHALS AGPATMMVFS VFYGLDWLAT VPPTVKLSIQ DFGKERGNMI FGWVVVAHQV GAAAAAYAAG AARDWFGTYS VPFVVAGFVC LFAALMSLRI ARARKLAHS //