ID K8QKI7_LACRH Unreviewed; 462 AA. AC K8QKI7; DT 06-FEB-2013, integrated into UniProtKB/TrEMBL. DT 06-FEB-2013, sequence version 1. DT 22-JAN-2014, entry version 8. DE SubName: Full=PTS system mannose-specific IIA/IIB/IIC component; DE EC=2.7.1.69; GN ORFNames=LRHMDP2_30; OS Lactobacillus rhamnosus LRHMDP2. OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae; OC Lactobacillus. OX NCBI_TaxID=1203258; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=LRHMDP2; RX PubMed=23405363; RA Chen Z., Wilkins M.R., Hunter N., Nadkarni M.A.; RT "Draft Genome Sequences of Two Clinical Isolates of Lactobacillus RT rhamnosus from Initial Stages of Dental Pulp Infection."; RL Genome Announc. 1:E00073-12(2013). CC -!- CATALYTIC ACTIVITY: Protein EIIB N(pi)-phospho-L- CC histidine/cysteine + sugar = protein EIIB + sugar phosphate. CC -!- SIMILARITY: Contains PTS EIIB type-2 domain. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AMQW01000001; EKS53789.1; -; Genomic_DNA. DR EnsemblBacteria; EKS53789; EKS53789; LRHMDP2_30. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:UniProtKB-EC. DR GO; GO:0005351; F:sugar:hydrogen symporter activity; IEA:InterPro. DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW. DR InterPro; IPR013011; PTS_EIIB_2. DR InterPro; IPR003501; PTS_EIIB_2/3. DR InterPro; IPR003352; PTS_EIIC. DR InterPro; IPR013014; PTS_EIIC_2. DR InterPro; IPR006327; PTS_IIC_fruc. DR Pfam; PF02378; PTS_EIIC; 1. DR Pfam; PF02302; PTS_IIB; 1. DR TIGRFAMs; TIGR01427; PTS_IIC_fructo; 1. DR PROSITE; PS51099; PTS_EIIB_TYPE_2; 1. DR PROSITE; PS51104; PTS_EIIC_TYPE_2; 1. PE 4: Predicted; KW Cell membrane; Membrane; Phosphotransferase system; Sugar transport; KW Transferase; Transmembrane; Transmembrane helix; Transport. SQ SEQUENCE 462 AA; 47485 MW; B29FD4A6393858F6 CRC64; MAAEKLQKTG QSDGYKVKVE TQGASGTEDT LTADDIKAAD FVVLAIDVAI DGMERFVGKR VVFSTTAEAI KDPQKLIDAG KHAEVYTGEK QHGDEQETSD ADDSGHEQSP VIKQLLNGVS HMIPFVVIGG LFIALSIALG GHATAKGMVV APNTIWSTMN QIGTIGFSLM IPILAGFIAY AIAGRAALAP AMVGAMVANT PAILGTKAGT GFLGAILVGY AAGYLTKWMN SWPIPKSLRA VMPIFVIPLL GTAVICAAFV YLLGSPISWL MTALQNLLTF LSKSPSTSIV LGLVLGAMVS VDMGGPVNKV AFLFGVASIT AGTPEIMGAV ACAIAVPPLS AGIATLFKSE LTTNEEKTAG VSAILMGLIG ITEGAIPLAT AHPKQVFPGI IIGSGVASAV GMIFHITDAV PHGGPIVGVL GATNNLGLFF LAILIGVLVS TAIIVLLKQH TVAHQKKLAA AK //