ID K7ENC1_HUMAN Unreviewed; 163 AA. AC K7ENC1; DT 09-JAN-2013, integrated into UniProtKB/TrEMBL. DT 09-JAN-2013, sequence version 1. DT 29-MAY-2024, entry version 59. DE SubName: Full=Purine-rich element-binding protein gamma {ECO:0000313|Ensembl:ENSP00000466881}; DE Flags: Fragment; GN Name=PURG {ECO:0000313|Ensembl:ENSP00000466881}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000466881, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000466881, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16421571; DOI=10.1038/nature04406; RA Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M., RA Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L., RA Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S., RA Asakawa T., Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A., RA Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III, RA Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., RA Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P., RA Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H., RA Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B., RA O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K., RA Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L., RA Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G., RA Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W., RA Platzer M., Shimizu N., Lander E.S.; RT "DNA sequence and analysis of human chromosome 8."; RL Nature 439:331-335(2006). RN [2] {ECO:0000313|Ensembl:ENSP00000466881} RP IDENTIFICATION. RG Ensembl; RL Submitted (NOV-2012) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC -!- SIMILARITY: Belongs to the PUR DNA-binding protein family. CC {ECO:0000256|ARBA:ARBA00009251}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC008066; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC084736; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR AlphaFoldDB; K7ENC1; -. DR SMR; K7ENC1; -. DR MassIVE; K7ENC1; -. DR MaxQB; K7ENC1; -. DR PeptideAtlas; K7ENC1; -. DR Antibodypedia; 23258; 107 antibodies from 16 providers. DR Ensembl; ENST00000523392; ENSP00000466881; ENSG00000172733. DR UCSC; uc064lty.1; human. DR HGNC; HGNC:17930; PURG. DR OpenTargets; ENSG00000172733; -. DR VEuPathDB; HostDB:ENSG00000172733; -. DR HOGENOM; CLU_1630853_0_0_1; -. DR OMA; FHCCQIQ; -. DR ChiTaRS; PURG; human. DR Proteomes; UP000005640; Chromosome 8. DR Bgee; ENSG00000172733; Expressed in sperm and 127 other cell types or tissues. DR ExpressionAtlas; K7ENC1; baseline and differential. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0045202; C:synapse; IEA:Ensembl. DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter. DR GO; GO:0032422; F:purine-rich negative regulatory element binding; IEA:InterPro. DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:InterPro. DR Gene3D; 3.30.2450.30; -; 1. DR InterPro; IPR006628; PUR-bd_fam. DR PANTHER; PTHR12611; PUR-TRANSCRIPTIONAL ACTIVATOR; 1. DR PANTHER; PTHR12611:SF3; PURINE-RICH ELEMENT-BINDING PROTEIN GAMMA; 1. DR Pfam; PF04845; PurA; 1. DR SMART; SM00712; PUR; 1. PE 1: Evidence at protein level; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Proteomics identification {ECO:0007829|PeptideAtlas:K7ENC1, KW ECO:0007829|ProteomicsDB:K7ENC1}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT REGION 1..40 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 133..163 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 133..150 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 163 FT /evidence="ECO:0000313|Ensembl:ENSP00000466881" SQ SEQUENCE 163 AA; 17886 MW; A2209DE43CC6EF6C CRC64; MERARRRGGG GGRGRGGKNV GGSGLSKSRL YPQAQHSHYP HYAASATPNQ AGGAAEIQEL ASKRVDIQKK RFYLDVKQSS RGRFLKIAEV WIGRGRQDNI RKSKLTLSLS VAAELKDCLG DFIEHYAHLG LKGHRQEHGH SKEQGSRRRQ KHSAPSPPVS VGS //