ID K0JR33_SACES Unreviewed; 261 AA. AC K0JR33; DT 28-NOV-2012, integrated into UniProtKB/TrEMBL. DT 28-NOV-2012, sequence version 1. DT 09-JAN-2013, entry version 2. DE SubName: Full=Type III pantothenate kinase; DE EC=2.7.1.33; GN Name=coaX; OrderedLocusNames=BN6_03660; OS Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / OS NBRC 15066 / NRRL 15764). OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Pseudonocardineae; Pseudonocardiaceae; Saccharothrix. OX NCBI_TaxID=1179773; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764; RX PubMed=22958348; DOI=10.1186/1471-2164-13-465; RA Strobel T., Al-Dilaimi A., Blom J., Gessner A., Kalinowski J., RA Luzhetska M., Puhler A., Szczepanowski R., Bechthold A., Ruckert C.; RT "Complete genome sequence of Saccharothrix espanaensis DSM 44229T and RT comparison to the other completely sequenced Pseudonocardiaceae."; RL BMC Genomics 13:465-465(2012). CC -!- FUNCTION: Catalyzes the phosphorylation of pantothenate (Pan), the CC first step in CoA biosynthesis (By similarity). CC -!- CATALYTIC ACTIVITY: ATP + (R)-pantothenate = ADP + (R)-4'- CC phosphopantothenate. CC -!- COFACTOR: Monovalent cations (By similarity). CC -!- PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; CoA from CC (R)-pantothenate: step 1/5. CC -!- SUBUNIT: Homodimer (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; HE804045; CCH27697.1; -; Genomic_DNA. DR UniPathway; UPA00241; UER00352. DR GO; GO:0004594; F:pantothenate kinase activity; IEA:EC. DR GO; GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:InterPro. DR HAMAP; MF_01274; Pantothen_kinase_3; 1; -. DR InterPro; IPR004619; Type_III_PanK. DR Pfam; PF03309; Pan_kinase; 1. DR TIGRFAMs; TIGR00671; baf; 1. PE 3: Inferred from homology; KW ATP-binding; Coenzyme A biosynthesis; Complete proteome; Cytoplasm; KW Kinase; Nucleotide-binding; Transferase. SQ SEQUENCE 261 AA; 27793 MW; A31EB370C92CEE4E CRC64; MLLAIDVGNT NIVLGLYDGT GDKAALVRDW RMRTDARMTA DELALTMRGL LGEYADKITG ISALSTVPAV LRELRVMLGR YYSAVPKVLV EPGVRTGVPL LVDNPKEVGS DRVINTLAAH HLHSTACVVV DFGTSTNLDV ISAKGEFLGG ALAPGIEISV DALAARAAQL RKVELVRPRS VIGKNTVECL QSGIVYGFVG QVDGLVRRIV DELQVSEPGP VTVIATGGLA PLVVTESATI HAHVPDLTLL GLRLVFERNM R //