ID J3NSY4_GAGT3 Unreviewed; 562 AA. AC J3NSY4; DT 03-OCT-2012, integrated into UniProtKB/TrEMBL. DT 03-OCT-2012, sequence version 1. DT 15-FEB-2017, entry version 23. DE SubName: Full=Acetolactate synthase {ECO:0000313|EMBL:EJT79297.1}; GN Name=GGTG_04383 {ECO:0000313|EnsemblFungi:GGTG_04383T0}; GN ORFNames=GGTG_04383 {ECO:0000313|EMBL:EJT79297.1}; OS Gaeumannomyces graminis var. tritici (strain R3-111a-1) (Wheat and OS barley take-all root rot fungus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Sordariomycetidae; Magnaporthales; Magnaporthaceae; OC Gaeumannomyces. OX NCBI_TaxID=644352; RN [1] {ECO:0000313|EnsemblFungi:GGTG_04383T0} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=R3-111a-1 {ECO:0000313|EnsemblFungi:GGTG_04383T0}; RG The Broad Institute Genome Sequencing Platform; RA Ma L.-J., Dead R., Young S., Zeng Q., Koehrsen M., Alvarado L., RA Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M., RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T., RA Howarth C., Jen D., Larson L., Mehta T., Neiman D., Pearson M., RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., RA Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.; RT "The genome sequence of Gaeumannomyces graminis var. tritici strain RT R3-111a-1."; RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:EJT79297.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=R3-111a-1 {ECO:0000313|EMBL:EJT79297.1}; RG The Broad Institute Genome Sequencing Platform; RG Broad Institute Genome Sequencing Center for Infectious Disease; RA Ma L.-J., Dead R., Young S., Zeng Q., Koehrsen M., Alvarado L., RA Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M., RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T., RA Howarth C., Jen D., Larson L., Mehta T., Neiman D., Pearson M., RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., RA Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.; RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:EJT79297.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=R3-111a-1 {ECO:0000313|EMBL:EJT79297.1}; RG The Broad Institute Genome Sequencing Platform; RA Ma L.-J., Dead R., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., RA Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., RA Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., RA Larson L., Lui A., MacDonald P.J.P., Mehta T., Montmayeur A., RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., RA Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Yandava C., RA Wortman J., Nusbaum C., Birren B.; RT "Annotation of Gaeumannomyces graminis var. tritici R3-111a-1."; RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases. RN [4] {ECO:0000313|EnsemblFungi:GGTG_04383T0} RP IDENTIFICATION. RC STRAIN=R3-111a-1 {ECO:0000313|EnsemblFungi:GGTG_04383T0}; RG EnsemblFungi; RL Submitted (JUN-2015) to UniProtKB. CC -!- SIMILARITY: Belongs to the TPP enzyme family. CC {ECO:0000256|RuleBase:RU362132}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; ADBI01000374; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; GL385396; EJT79297.1; -; Genomic_DNA. DR RefSeq; XP_009220442.1; XM_009222178.1. DR EnsemblFungi; GGTG_04383T0; GGTG_04383T0; GGTG_04383. DR GeneID; 20344841; -. DR OrthoDB; EOG092C1DJV; -. DR Proteomes; UP000006039; Unassembled WGS sequence. DR GO; GO:0003984; F:acetolactate synthase activity; IEA:InterPro. DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro. DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro. DR GO; GO:0034077; P:butanediol metabolic process; IEA:InterPro. DR Gene3D; 3.40.50.1220; -; 1. DR Gene3D; 3.40.50.970; -; 2. DR InterPro; IPR012782; Acetolactate_synth_catblc. DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom. DR InterPro; IPR029061; THDP-binding. DR InterPro; IPR012000; Thiamin_PyroP_enz_cen_dom. DR InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom. DR InterPro; IPR011766; TPP_enzyme-bd_C. DR Pfam; PF02775; TPP_enzyme_C; 1. DR Pfam; PF00205; TPP_enzyme_M; 1. DR Pfam; PF02776; TPP_enzyme_N; 1. DR SUPFAM; SSF52467; SSF52467; 2. DR SUPFAM; SSF52518; SSF52518; 2. DR TIGRFAMs; TIGR02418; acolac_catab; 1. PE 3: Inferred from homology; KW Complete proteome {ECO:0000313|Proteomes:UP000006039}; KW Reference proteome {ECO:0000313|Proteomes:UP000006039}; KW Thiamine pyrophosphate {ECO:0000256|RuleBase:RU362132}. FT DOMAIN 6 164 TPP_enzyme_N. {ECO:0000259|Pfam:PF02776}. FT DOMAIN 191 326 TPP_enzyme_M. {ECO:0000259|Pfam:PF00205}. FT DOMAIN 393 542 TPP_enzyme_C. {ECO:0000259|Pfam:PF02775}. SQ SEQUENCE 562 AA; 60342 MW; AE9D2B3B0265A3EF CRC64; MASQQNTVQV VIDSLKAAGV TIVFGDSVFN ALVDHPEIKV VVCRHEQNAA FIAGAVGKLT DRPGVVIVTS GPGTSNLVTG LVTATDEGSP VVAIAGSVRR VQSARRTHQS LQGVELLRPV TKKVVAALVE DQVAELVADA FRVAATFPRG ATAVSLPIDI MSSTSLTAFP ALPASTFRPP QLGPAPNALL ARTVEMLGRA KFPVLFLGMR ASSARVVEAV HALLRQHPIP VIETFQAAGA ISRELAHLFY GRVGLFRNQA GDRLLARADL VLAIGYDEAE YDSSQWNPTP GRFDIIHMDY QPANVGPNYE PAVELVGSLV ENLRSLTARL ADAGVAVARP QDTDDGRHIF EDFHAWESSE KAVGRPAEGP VHPLQFIRTL QDLIAPESVV TCDVGSVYIY MCRYFYSYTP KTFLVSNAQQ TLGVALPWAI GASLSQDPPC SKKVVSISGD GGFQFSGQEL ATAVLQGCKI AHFIWNDSKY NMVEFQEVDK YGRSAGVELG GVDFVKYAEA YGALGLRART PAELEGVVRE ALAHDGVCLV DVEIDYSSNH ELMQHVIADS VV //