ID J3B2Y4_9PSED Unreviewed; 487 AA. AC J3B2Y4; DT 03-OCT-2012, integrated into UniProtKB/TrEMBL. DT 03-OCT-2012, sequence version 1. DT 11-MAY-2016, entry version 26. DE RecName: Full=UDP-N-acetylmuramyl-tripeptide synthetase {ECO:0000256|SAAS:SAAS00085409}; DE EC=6.3.2.- {ECO:0000256|SAAS:SAAS00276926}; GN ORFNames=PMI31_01108 {ECO:0000313|EMBL:EJM76848.1}; OS Pseudomonas sp. GM55. OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; OC Pseudomonadaceae; Pseudomonas. OX NCBI_TaxID=1144333 {ECO:0000313|EMBL:EJM76848.1, ECO:0000313|Proteomes:UP000007268}; RN [1] {ECO:0000313|EMBL:EJM76848.1, ECO:0000313|Proteomes:UP000007268} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=GM55 {ECO:0000313|EMBL:EJM76848.1, RC ECO:0000313|Proteomes:UP000007268}; RX PubMed=23045501; DOI=10.1128/JB.01243-12; RA Brown S.D., Utturkar S.M., Klingeman D.M., Johnson C.M., Martin S.L., RA Land M.L., Lu T.Y., Schadt C.W., Doktycz M.J., Pelletier D.A.; RT "Twenty-one genome sequences from Pseudomonas species and 19 genome RT sequences from diverse bacteria isolated from the rhizosphere and RT endosphere of Populus deltoides."; RL J. Bacteriol. 194:5991-5993(2012). CC -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis. CC {ECO:0000256|RuleBase:RU004135, ECO:0000256|SAAS:SAAS00085391}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU004135, CC ECO:0000256|SAAS:SAAS00085486}. CC -!- SIMILARITY: Belongs to the MurCDEF family. MurE subfamily. CC {ECO:0000256|SAAS:SAAS00569976}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:EJM76848.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AKJJ01000032; EJM76848.1; -; Genomic_DNA. DR RefSeq; WP_008016696.1; NZ_AKJJ01000032.1. DR EnsemblBacteria; EJM76848; EJM76848; PMI31_01108. DR UniPathway; UPA00219; -. DR Proteomes; UP000007268; Unassembled WGS sequence. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW. DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW. DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW. DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-UniPathway. DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW. DR Gene3D; 3.40.1190.10; -; 1. DR Gene3D; 3.40.1390.10; -; 1. DR Gene3D; 3.90.190.20; -; 1. DR HAMAP; MF_00208; MurE; 1. DR InterPro; IPR004101; Mur_ligase_C. DR InterPro; IPR013221; Mur_ligase_cen. DR InterPro; IPR000713; Mur_ligase_N. DR InterPro; IPR005761; UDP-N-AcMur-Glu-dNH2Pim_ligase. DR Pfam; PF01225; Mur_ligase; 1. DR Pfam; PF02875; Mur_ligase_C; 1. DR Pfam; PF08245; Mur_ligase_M; 1. DR SUPFAM; SSF53244; SSF53244; 1. DR SUPFAM; SSF53623; SSF53623; 1. DR SUPFAM; SSF63418; SSF63418; 1. DR TIGRFAMs; TIGR01085; murE; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|SAAS:SAAS00459289}; KW Cell cycle {ECO:0000256|RuleBase:RU004135, KW ECO:0000256|SAAS:SAAS00459322}; KW Cell division {ECO:0000256|RuleBase:RU004135, KW ECO:0000256|SAAS:SAAS00459379}; KW Cell shape {ECO:0000256|RuleBase:RU004135, KW ECO:0000256|SAAS:SAAS00459388}; KW Cell wall biogenesis/degradation {ECO:0000256|RuleBase:RU004135, KW ECO:0000256|SAAS:SAAS00459257}; KW Complete proteome {ECO:0000313|Proteomes:UP000007268}; KW Cytoplasm {ECO:0000256|SAAS:SAAS00459408}; KW Ligase {ECO:0000256|SAAS:SAAS00459363}; KW Nucleotide-binding {ECO:0000256|SAAS:SAAS00459299}; KW Peptidoglycan synthesis {ECO:0000256|RuleBase:RU004135, KW ECO:0000256|SAAS:SAAS00459442}. FT DOMAIN 19 94 Mur_ligase. {ECO:0000259|Pfam:PF01225}. FT DOMAIN 106 306 Mur_ligase_M. {ECO:0000259|Pfam:PF08245}. FT DOMAIN 329 410 Mur_ligase_C. {ECO:0000259|Pfam:PF02875}. SQ SEQUENCE 487 AA; 52115 MW; 0DE81793E58C6663 CRC64; MSLSLNKIFP HAGHDLLIRE LALDSRKVRA GDLFLAVPGG KFDGRAHIAD ALQRGAAAVA YEVEGATVLP ITEVPLIPVK GLAAQLSDIA GRFYGEPSHH LNLVGVTGTN GKTSVTQLVA QALDLLGQHC GLVGTLGCGF YGSLESGLHT TPNPIAMQAT LADLKKAGAK AVAMEVSSHG LDQGRVTALA FDVAVMTNLS RDHLDYHGTM QAYGETKAKL FAWNDLKCRV VNLDDEFGRQ LAADEGESRL ITYSLEDSRA YLYCREAQFN DEGVRATLVT PQGEHLLRSA LLGRFNLSNV LAAVGALLGL DYALDEILKV LPMLEGPAGR MQRLGGGSQP LVVVDYAHTP DALEKVLLAL RPHAKGRLLC LFGCGGDRDR GKRPLMAEVV ERLADGVLVT DDNPRTEDPS VIFDDIRAGF TAVDKVEFVA GRGQAIARLI ASASVDDVIV LAGKGHEDYQ EINGERHAFS DLVEADHALT AWEVAHV //